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描述(由申请人提供):这项资助申请旨在帮助那些在计算系统生物学中开发新兴社区标准的研究人员前往位于康涅狄格州法明顿的R. D.柏林细胞分析和建模中心,该中心将主办2013年生物学建模资源黑客马拉松(HARMONY)会议。重点是在生物建模和数据分析中使用的四种核心社区接受的语言,标准和本体(SBML, BioPAX, SBGN和SED-ML),其用户和开发社区已经联合起来作为生物学计算建模网络(COMBINE)的一部分。会议的主要目的是改善格式之间的互操作性,并启动努力,以解决新发现的未满足需求或覆盖方面的重大差距。HARMONY会议已成为一个宝贵的场所,通过面对面的会议和实地领导人的亲身参与,讨论具体的高优先级问题,并为明显的绊脚石设计新的解决方案。会议将汇集领先的科学家和软件开发人员,生物建模,生物信息学和计算机科学方面的专家,他们积极参与标准和/或软件工具和使用它们的存储库的开发。会议的很大一部分将由黑客马拉松式的平行轨道组成,这些工作组的任务是
英文摘要
DESCRIPTION (provided by applicant): This grant application is designed to help the researchers who have been developing emerging community standards in computational systems biology to travel to the R. D. Berlin Center for Cell Analysis and Modeling in Farmington, CT, which will host the Hackathon on Resources in Modeling in Biology (HARMONY) 2013 meeting. The focus is on four core community-accepted languages, standards and ontologies used in biological modeling and data analysis (SBML, BioPAX, SBGN, and SED-ML), whose communities of users and developers have joined forces as part of the Computational Modeling in Biology network (COMBINE). The main purpose of the conference is to improve interoperability between formats and to jump-start efforts to address newly identified unmet needs or critical gaps in coverage. The HARMONY meetings have emerged as an invaluable venue for hashing out concrete high priority issues and devise new solutions for apparent stumbling blocks, with face-to-face meetings and hands-on participation of leaders in the field. The conference will bring together leading scientists and software developers, experts in biological modeling, bioinformatics and computer science, who are actively involved in the development of standards and/or the software tools and repositories that use them. A large part of the meeting will consist of hackathon-style parallel tracks of working groups that are tasked to address concrete problems and to produce deliverables such as draft specifications and/or prototype implementations. We wish to emphasize that most of the leading members of the different groups of the COMBINE network serve as volunteers and do not have dedicated funding for this activity, which is nonetheless crucial to the scientific community. It is importan that as many as possible of these researchers are present at the HARMONY conference. We are striving to maintain the cost of attending to a minimum and we will be able to organize the meeting without charging any registration fee. However, no support is available to directly defray the costs of travel for participants, which often does make up for most of the financial burden to attend meetings that have a global audience. We are therefore requesting funds to partially defray the travel costs for some of the key participants to the conference.
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Mechanistic Modeling of Cellular Systems
Mechanistic Modeling of Cellular Systems
Mechanistic Modeling of Cellular Systems
Mechanistic Modeling of Cellular Systems
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