Microbiology and Animal Resources Core Laboratory

微生物与动物资源核心实验室

• 批准号: 8375444
• 负责人: ANDREW B. ONDERDONK
• 金额: $ 104.32万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2014-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8375444
• 关键词: Bioterrorism; Categories; Clinical; Communities; Doctor of Philosophy; Emerging Communicable Diseases; Equipment; Event; Funding; Goals; Human Resources; Individual; Institutes; Institution; Intervention; Laboratories; Massachusetts; Microbiology; Mission; New England; Organism; Research; Research Activity; Research Infrastructure; Research Personnel; Research Training; Safety; Scientist; Seeds; Training; Translational Research; Visit; Work; animal facility; animal resource; biodefense; emergency service responder; flexibility; interest; laboratory facility; medical schools; outreach program; pathogen; product development; programs

NERCE Core A: Microbiology and Animal Resources Core Laboratory, Andrew Onderdonk, Ph.D., Harvard Medical School. The overall goal of the Core A laboratories is to provide the infrastructure, administrative support, scientific equipment and personnel for a BSL-2/ABSL-2 laboratory and animal facility for training and research with category A, B and C agents. This facility includes access to exempt and select agent strains, laboratory space for visiting investigators, and bio-safety and laboratory equipment for training prior to experimental work in the Core A BSL-3/ABSL-3 Select Agent laboratory and animal facility. Specific aims for the Core are to train NERCE scientists and technical personnel in the proper use of BSL-3/ABSL-3 facilities and to provide trained scientific staff to support investigators with research using Category A, B and C priority pathogens. An essential specific aim for the Core A laboratory is to prepare and fully characterize master and seed lot stocks of select agents and exempt strains for all NERCE investigators and to increase collaborative research activities with NERCE sponsored scientists and across NERCE core laboratories. As part of our overall mission, the Core A laboratory participates in translational research with Category A, B, and C organisms directed at development of products and clinical interventions for emerging infectious disease threats. Within the greater community, Core A also provides support through the LRN program to the Massachusetts State Laboratory Institute and others, as requested by the SLI, involved as first responders for possible BT events. The Core A laboratory promotes the use of facilities through an outreach program to other institutions and scientists throughout the New England region.

NERCE核心A：微生物学和动物资源核心实验室，Andrew Onderdonk博士， 哈佛医学院。 核心A实验室的总体目标是提供基础设施、行政支持、科学研究和技术支持。 BSL-2/ABSL-2实验室和动物设施的设备和人员，用于培训和研究， A、B和C类药剂。该设施包括获得豁免和精选病原体菌株、实验室 访问调查员的空间，以及实验前培训所需的生物安全和实验室设备 在Core A BSL-3/ABSL-3 Select Agent实验室和动物设施工作。核心的具体目标 培训NERCE科学家和技术人员正确使用BSL-3/ABSL-3设施， 提供经过培训的科学工作人员，以支持研究者使用A、B和C类优先级进行研究 病原体核心A实验室的一个基本具体目标是制备和充分表征主 为所有NERCE研究者提供选定制剂和豁免菌株的种子批库存，并增加 与NERCE赞助的科学家和NERCE核心实验室开展合作研究活动。作为 作为我们整体使命的一部分，核心A实验室参与A类，B类， 和C微生物，用于开发新出现的传染性疾病的产品和临床干预措施 疾病威胁。在更大的社区内，核心A还通过LRN计划提供支持， 马萨诸塞州国家实验室研究所和其他机构，应SLI的要求，首先参与 可能的BT事件的响应者。核心A实验室通过一个 该项目还将推广到整个新英格兰地区的其他机构和科学家。