Micreobiology and Animal Resources Core Laboratory

微生物与动物资源核心实验室

• 批准号: 7669761
• 负责人: ANDREW B. ONDERDONK
• 金额: $ 100.81万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-25 至 2014-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7669761
• 关键词: Bioterrorism; Categories; Clinical; Communities; Doctor of Philosophy; Emerging Communicable Diseases; Equipment; Event; Funding; Goals; Human Resources; Individual; Institutes; Institution; Intervention; Laboratories; Laboratory Animals; Massachusetts; Microbiology; Mission; New England; Organism; Research; Research Activity; Research Infrastructure; Research Personnel; Research Training; Safety; Scientist; Seeds; Training; Translational Research; Visit; Work; animal facility; animal resource; biodefense; emergency service responder; flexibility; interest; medical schools; outreach program; pathogen; product development; programs

NERCE Core A: Microbiology and Animal Resources Core Laboratory, Andrew Onderdonk, Ph.D., Harvard Medical School. The overall goal of the Core A laboratories is to provide the infrastructure, administrative support, scientific equipment and personnel for a BSL-2/ABSL-2 laboratory and animal facility for training and research with category A, B and C agents. This facility includes access to exempt and select agent strains, laboratory space for visiting investigators, and bio-safety and laboratory equipment for training prior to experimental work in the Core A BSL-3/ABSL-3 Select Agent laboratory and animal facility. Specific aims for the Core are to train NERCE scientists and technical personnel in the proper use of BSL-3/ABSL-3 facilities and to provide trained scientific staff to support investigators with research using Category A, B and C priority pathogens. An essential specific aim for the Core A laboratory is to prepare and fully characterize master and seed lot stocks of select agents and exempt strains for all NERCE investigators and to increase collaborative research activities with NERCE sponsored scientists and across NERCE core laboratories. As part of our overall mission, the Core A laboratory participates in translational research with Category A, B, and C organisms directed at development of products and clinical interventions for emerging infectious disease threats. Within the greater community, Core A also provides support through the LRN program to the Massachusetts State Laboratory Institute and others, as requested by the SLI, involved as first responders for possible BT events. The Core A laboratory promotes the use of facilities through an outreach program to other institutions and scientists throughout the New England region.

NERCE 核心 A：微生物学和动物资源核心实验室，Andrew Onderdonk 博士， 哈佛医学院。 核心 A 实验室的总体目标是提供基础设施、行政支持、科学 BSL-2/ABSL-2 实验室和动物设施的设备和人员，用于培训和研究 A、B、C 类药剂。该设施包括获得豁免和精选病原体菌株、实验室 供访问研究人员使用的空间，以及用于实验前培训的生物安全和实验室设备 在核心 A BSL-3/ABSL-3 选择代理实验室和动物设施中工作。核心的具体目标 培训 NERCE 科学家和技术人员正确使用 BSL-3/ABSL-3 设施，并 提供训练有素的科学人员来支持研究人员使用 A、B 和 C 类优先级进行研究 病原体。核心 A 实验室的一个重要具体目标是准备并充分表征母版 以及为所有 NERCE 研究人员提供精选药剂和豁免菌株的种子批次库存，并增加 与 NERCE 资助的科学家以及 NERCE 核心实验室的合作研究活动。作为 作为我们整体使命的一部分，核心 A 实验室参与 A、B 类转化研究， 和 C 生物体，旨在针对新出现的传染病开发产品和临床干预措施 疾病威胁。在更大的社区内，核心 A 还通过 LRN 计划提供支持 应 SLI 的要求，马萨诸塞州立实验室研究所和其他机构首先参与 可能的 BT 事件的响应者。核心 A 实验室通过以下方式促进设施的使用： 向整个新英格兰地区的其他机构和科学家开展外展计划。