Overall Center Research Strategy p118-129

总体中心研究策略 p118-129

• 批准号: 8595669
• 负责人: Peter G. Shields
• 金额: --
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-19 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8595669
• 关键词: Address; Adolescent; Adult; Advertising; Affective; Area; Awareness; Biometry; Cognitive; Cohort Studies; Complement; Data; Decision Making; Development; Environment; Faculty; Fostering; Funding; Individual; Investigation; Marketing; Modeling; Ohio; Persons; Pilot Projects; Population; Regulation; Research; Research Personnel; Research Priority; Research Training; Resource Sharing; Resources; Rural; Rural Population; Science; Series; Smokeless Tobacco; Students; Surveys; TNFRSF5 gene; Tobacco; Training and Education; Universities; Urban Population; Vision; Youth; design; disorder risk; post-doctoral training; preference; research study

The overall vision of The Ohio State University Center of Excellence in Regulatory Tobacco Science (OSU-CERTS) is to serve as a national leader in providing relevant scientific data to support FDA regulatory decision making in the Center for Tobacco Products. The overall theme of OSU-CERTS is to understand the reasons for underiying tobacco-product preferences, especially dual and poly-use, and how these reasons influence use in an environment of ever-changing diverse types of tobacco products. The Center will integrate this theme in a series of adolescent and adult cohort studies conducted in natural settings, complemented by well-controlled experimental studies that allow for causal inference. To accomplish the above, we will utilize a population harm model (Figure 1), where harm to the population is the result of individual disease risk and the number of persons who are exposed. The major research areas of the OSUCERTs that will assist the FDA include the impact of advertising and marketing; cognitive and affective influences in decision making; a focus on smokeless tobacco (ST) and dual use; use of both urban and rural populations to enhance generalizability; and synergistic studies that cover the range of tobacco users from adolescents to adults. Our Center will address 11 of 56 research priorities set forth by the FDA in January, 2012.

俄亥俄州立大学监管卓越中心的整体愿景 烟草科学（OSU-CERTS）是在提供相关科学数据以支持的国家领导者 烟草产品中心的FDA监管决策。 OSU-Certs的总体主题是 了解不足的烟草产品偏好（尤其是双重和多用途）的原因，以及如何 这些原因影响在不断变化的多种烟草产品的环境中使用。这 中心将将这一主题整合到一系列在自然环境中进行的青少年和成人队列研究中， 辅以良好控制的实验研究，可以进行因果推断。完成 上面，我们将利用人口危害模型（图1），其中对人口的伤害是 个体疾病的风险和暴露的人数。 Osucerts的主要研究领域 这将有助于FDA包括广告和营销的影响；认知和情感 决策的影响；专注于无烟烟草（ST）和双重用途；使用城市和农村 人口增强可推广性；以及涵盖来自烟草用户范围的协同研究 成年人的青少年。我们的中心将解决FDA一月份提出的56项研究优先事项中的11个 2012。