Overall Center Research Strategy p118-129

总体中心研究策略 p118-129

• 批准号: 8595669
• 负责人: Peter G. Shields
• 金额: --
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-19 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8595669
• 关键词: Address; Adolescent; Adult; Advertising; Affective; Area; Awareness; Biometry; Cognitive; Cohort Studies; Complement; Data; Decision Making; Development; Environment; Faculty; Fostering; Funding; Individual; Investigation; Marketing; Modeling; Ohio; Persons; Pilot Projects; Population; Regulation; Research; Research Personnel; Research Priority; Research Training; Resource Sharing; Resources; Rural; Rural Population; Science; Series; Smokeless Tobacco; Students; Surveys; TNFRSF5 gene; Tobacco; Training and Education; Universities; Urban Population; Vision; Youth; design; disorder risk; post-doctoral training; preference; research study

The overall vision of The Ohio State University Center of Excellence in Regulatory Tobacco Science (OSU-CERTS) is to serve as a national leader in providing relevant scientific data to support FDA regulatory decision making in the Center for Tobacco Products. The overall theme of OSU-CERTS is to understand the reasons for underiying tobacco-product preferences, especially dual and poly-use, and how these reasons influence use in an environment of ever-changing diverse types of tobacco products. The Center will integrate this theme in a series of adolescent and adult cohort studies conducted in natural settings, complemented by well-controlled experimental studies that allow for causal inference. To accomplish the above, we will utilize a population harm model (Figure 1), where harm to the population is the result of individual disease risk and the number of persons who are exposed. The major research areas of the OSUCERTs that will assist the FDA include the impact of advertising and marketing; cognitive and affective influences in decision making; a focus on smokeless tobacco (ST) and dual use; use of both urban and rural populations to enhance generalizability; and synergistic studies that cover the range of tobacco users from adolescents to adults. Our Center will address 11 of 56 research priorities set forth by the FDA in January, 2012.

俄亥俄州州立大学卓越监管中心的总体愿景 烟草科学（OSU-CERTS）将在提供相关科学数据方面发挥国家领导作用， FDA在烟草产品中心的监管决策。OSU-CERTS的总体主题是 了解烟草产品偏好的原因，特别是双重用途和多种用途，以及如何 这些原因影响了在不断变化的多种类型的烟草产品的环境中的使用。的 中心将把这一主题纳入一系列在自然环境中进行的青少年和成人队列研究， 并辅之以控制良好的实验研究，以进行因果推理。完成 在上文中，我们将利用人口危害模型（图1），其中对人口的危害是以下因素的结果： 个人疾病风险和接触人数。OSUCERT的主要研究领域 包括广告和营销的影响;认知和情感 对决策的影响;关注无烟烟草和双重用途;城市和农村都使用 以及涵盖烟草使用者范围的协同研究， 从青少年到成年人我们的中心将解决FDA在1月份提出的56个研究重点中的11个， 2012.