2021 Mitochondria in Health and Disease Gordon Research Conference

2021 年线粒体健康与疾病戈登研究会议

• 批准号: 10236763
• 负责人: Nika N Danial
• 金额: $ 3.8万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-02-01 至 2024-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10236763
• 关键词: Acceleration; Aging; Area; Awareness; Basic Science; Behavior; Biochemistry; Bioenergetics; Biogenesis; Biological; Biology; Cardiovascular Diseases; Categories; Cells; Collaborations; Communication; Communities; Development; Diabetes Mellitus; Disease; Environment; Fellowship; Female; Fertilization; Fostering; Functional disorder; Funding; Genetic; Genome; Goals; Health; Hour; Human; Inborn Errors of Metabolism; International; Investigation; Iron; Italy; Knowledge; Malignant Neoplasms; Medicine; Mentors; Metabolism; Minority; Mitochondria; Mitochondrial Diseases; Molecular; National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; Nerve Degeneration; Obesity; Organelles; Oxidation-Reduction; Participant; Pathology; Pathway interactions; Patients; Physiology; Postdoctoral Fellow; Productivity; Proteins; Proteome; Regulation; Renaissance; Request for Applications; Research; Research Personnel; Schedule; Science; Scientist; Series; Source; System; Time; Tissues; Training; Translational Research; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Woman; age related; career; career development; cost; diversity and inclusion; drug discovery; frontier; genome integrity; graduate student; interest; meetings; metabolome; multidisciplinary; multiple omics; novel; posters; programs; proteostasis; rapid growth; symposium; trafficking

PROJECT SUMMARY This application seeks partial funds to support the Gordon Research Conference (GRC) on Mitochondria in Health and Disease to be held August 8-13, 2021. This is the second in a new series of GRCs, which emerged from the growing awareness within the mitochondrial community of the need for a forum to capture and integrate a wide range of rapidly evolving areas of mitochondrial biology from the perspective of both basic and translational science. The GRC format is particularly suited for this forum because it provides a setting where cutting edge unpublished findings are presented in an inclusive environment that attracts experts across labs worldwide for a five-day conference. Time for discussions and networking are rigorously protected and encouraged in every scientific session and through free times in the afternoons. A setting where open discussion takes place encourages collaboration and is crucial to advancing the frontiers of mitochondrial science. In addition to accelerating mitochondrial research and promoting cross-disciplinary collaborations, the conference is committed to enhance visibility and participation of women scientists and minorities. As such, 44% of confirmed speakers and 44% of discussion leaders in the conference program are women. In addition, short talks from abstracts will be prioritized to feature research by early career scientists, trainees, women and minorities. Moreover, a GRC-sponsored Power Hour, which is an open communication forum, is scheduled early during the conference to discuss challenges surrounding diversity in science. Another conference objective is to train graduate students and postdocs in mitochondrial science and provide networking and informal mentoring opportunities to enrich their career development. The format of the 2021 conference consists of 9 scientific sessions each composed of 3 full talks and one short talk selected from abstracts, as well as 4 two-hour poster sessions. The scientific sessions will have an integrative focus on novel molecular, cellular and organismal aspects of mitochondrial bioenergetics and metabolism, redox regulation, genome integrity, protein biogenesis, and proteostasis, and mitochondria-based crosstalk mechanisms via carrier systems as well as interorganellar communications. Each session has a mixture of talks ranging from fundamental biologic mechanisms to physiology/pathophysiology. As such, the program includes highly diverse topics while featuring frontiers of knowledge gained from a broad range of approaches, experimental systems and tissue types, as well as investigation of multiple diseases involving alterations in mitochondrial function. The scientific sessions feature outstanding mitochondrial biologists ranging from established investigators to early career scientists whose cutting-edge research has had high impact in the fields of aging, cancer, diabetes and obesity, cardiovascular disease, neurodegeneration, and inborn errors of metabolism. Given the collective breadth of expertise and research interests within the mitochondrial community, we believe our program will catalyze productive cross-disciplinary interactions to propel the field forward.

项目摘要 该申请寻求部分资金，以支持戈登研究会议（GRC）的线粒体， 健康与疾病将于2021年8月8日至13日举行。这是新一系列GRCs中的第二个， 从线粒体社区越来越意识到需要一个论坛来捕捉和整合 线粒体生物学的一个广泛的快速发展的领域，从基础和 转化科学GRC格式特别适合此论坛，因为它提供了一种设置， 未发表的前沿研究结果在一个包容的环境中呈现，吸引了各实验室的专家 在全球范围内举行为期五天的会议。讨论和建立网络的时间受到严格保护， 在每一个科学会议和下午的自由时间鼓励。一个公开讨论 鼓励合作，对推进线粒体科学的前沿至关重要。在 除了加速线粒体研究和促进跨学科合作外， 致力于提高女科学家和少数群体的知名度和参与度。因此，44%的确认 会议方案中的发言人和44%的讨论领导人是妇女。此外，来自 摘要将优先突出早期职业科学家、受训人员、妇女和少数民族的研究。 此外，GRC赞助的Power Hour是一个开放的交流论坛， 会议讨论围绕科学多样性的挑战。会议的另一个目标是培训 研究生和博士后在线粒体科学，并提供网络和非正式的指导 丰富他们的职业发展机会。 2021年会议的形式包括9个科学会议，每个会议由3个完整的会谈和一个 从摘要中选出的简短演讲，以及4个两小时的海报会议。科学会议将有一个 综合关注线粒体生物能量学的新分子、细胞和有机体方面， 代谢、氧化还原调节、基因组完整性、蛋白质生物发生和蛋白质稳态，以及基于 通过载波系统以及细胞间通信的串扰机制。每个会话都有一个 从基本的生物学机制到生理学/病理生理学的讲座。因此， 该计划包括高度多样化的主题，同时具有从广泛的知识领域获得的前沿知识， 方法，实验系统和组织类型，以及涉及多种疾病的研究 线粒体功能的改变。科学会议的特点是杰出的线粒体生物学家， 从已建立的调查人员到早期的职业科学家，他们的前沿研究在世界范围内产生了很大的影响。 衰老、癌症、糖尿病和肥胖、心血管疾病、神经变性和先天性缺陷等领域的研究。 新陈代谢.鉴于线粒体群体内专业知识和研究兴趣的集体广度， 我们相信，我们的计划将促进富有成效的跨学科的互动，推动该领域的发展。