Influence of cortical stroke and experimental brain stimulation on excitability of human corticobulbar motor projections and swallowing function

皮质中风和实验性脑刺激对人类皮质延髓运动投射和吞咽功能兴奋性的影响

• 批准号: nhmrc : 1013320
• 负责人: Dr Sebastian Doeltgen
• 金额: $ 8.68万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/influence-cortical-stroke-swallowing-function/109709
• 关键词: Influence; cortical; stroke; experimental; brain

Swallowing disorders often result from damage to the brain. They have profound consequences on patient health and quality of life and result in significant medical and socioeconomic costs. This project firstly investigates how motor networks in the brain control the muscles involved in swallowing and how this control is affected by stroke. Secondly, it evaluates the potential of novel interventions to improve impaired swallowing function following stroke by reorganising motor networks.

吞咽障碍通常是由大脑受损引起的。它们对患者的健康和生活质量产生深远的影响，并导致重大的医疗和社会经济成本。该项目首先研究了大脑中的运动网络如何控制参与吞咽的肌肉，以及这种控制如何受到中风的影响。其次，它评估了通过重组运动网络来改善卒中后吞咽功能受损的新干预措施的潜力。