Plan for Cardiovascular Research Training in Advanced Biostatistics, Aging, and H

高级生物统计学、衰老和健康方面的心血管研究培训计划

• 批准号: 8515404
• 负责人: Dorairaj Prabhakaran
• 金额: $ 2.92万
• 依托单位: CENTRE FOR CHRONIC DISEASE CONTROL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-17 至 2015-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8515404
• 关键词: Address; Aging; Appointment; Area; Award; Biometry; Cardiovascular system; Chicago; Chronic; Chronic Disease; Clinical Research; Collaborations; Communicable Diseases; Complement; Country; Data Collection; Demographic Transitions; Development; Diabetes Mellitus; Disease; Education; Endocrinology; Epidemiologic Studies; Epidemiologist; Equipment and supply inventories; Evaluation; Event; Faculty; Fellowship; Funding; Future; Grant; Health; Health Policy; Income; India; Institutes; Institution; International; International AIDS; Lead; Life; Light; Longevity; Mali; Medical; Medical Education; Medical Research; Mentors; Modeling; National Heart, Lung, and Blood Institute; Nigeria; Obesity; Postdoctoral Fellow; Preventive Medicine; Principal Investigator; Quality Control; Research; Research Infrastructure; Research Institute; Research Personnel; Research Project Grants; Research Training; Role; Science; Scientist; Site; Training; Training Programs; United States National Institutes of Health; Universities; cardiovascular disorder epidemiology; disorder control; experience; global health; health training; post-doctoral training; pre-doctoral; programs; research and development; responsible research conduct; success; surveillance data

Plan for Cardiovascular Research Training in Advanced Biostatistics, Aging, and Health Policy Modeling in India. DESCRIPTION (provided by applicant): The proposed application aims to develop and refine research training program activities for future pre- and post-doctoral research fellows from the Centre for Chronic Disease Control (CCDC) in New Delhi, India, in partnership with Northwestern University in Chicago, USA and All India Institute of Medical Sciences (AIIMS) in New Delhi, India in 3 target areas: 1) advanced cardiovascular biostatistics, 2) cardiovascular health and aging, 3) cardiovascular health policy modeling in order to apply for the Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43) during Year 2. The Objectives outlined above address strategic needs for CCDC and leverage existing, successful collaborations between CCDC, Northwestern, AIIMS, and their respective partner institutions. CCDC is a leading non-profit research institute India and is led by Dr. D. Prabhakaran (Principal Investigator on current D71 proposal). Dr. Prabhakaran, a cardiologist and epidemiologist, has extensive post- doctoral research training experience and is currently the Principal Investigator of the NHLBI/UnitedHealth- funded Global Center of Excellence in New Delhi. He is also the Site Director of the Fogarty International Clinical Research Scholars' and Fellows' Programs. The expansion of cardiovascular epidemiology funding and research in India has not been matched with a commensurate expansion of biostatistical training, a gap that will grow as data collection increases from many large epidemiologic studies in which CCDC either leads or participates. Research training in cardiovascular health and aging complements the current D43 grant at CCDC (D43 PI: Nikhil Tandon [consortium PD/PI on current D71 proposal]), which focuses on the role of early life events in the development of chronic diseases such as obesity and diabetes. The relationship between cardiovascular health and aging is particularly relevant in light of the predicted demographic transition in India. Cardiovascular health policy modeling research is also limited in low- and middle-income countries (LMIC), including India. While scientists call for evidence-informed policymaking, there is a dearth of cardiovascular health modeling that can provide guidance to policymakers when critical surveillance data are scarce. CCDC lacks expertise in these 3 target areas, and pre- and post-doctoral research training would address these needs. The Department of Preventive Medicine at Northwestern has a long track record of research and pre- and post-doctoral research training in these 3 target areas to help address these needs. Northwestern has also demonstrated successful training of post-doctoral fellows from the US, through its ongoing T32 training grant in cardiovascular epidemiology (T32 co-director: Dr. Kiang Liu [co-investigator on current D71 proposal]), and of fellows from LMIC (Dr. Liu). CCDC and Northwestern have demonstrated prior collaborative success through Dr. Mark Huffman's (collaborator) Fogarty International Clinical Research fellowship (co-mentors, Drs. D. Prabhakaran and Lloyd-Jones [consortium PD/PI on current D71 proposal]) and NIH K99/R00 grant. Dr. Robert Murphy, director of the Northwestern University Center for Global Health, has extensive experience in global health training as the PI of two NIH/Fogarty-funded programs: Medical Education Partnership Initiative (MEPI) in Nigeria (including a supplemental grant for training on the responsible conduct of research), AIDS International Training and Research Program (AITRP) in Nigeria and Mali. Dr. Murphy has a track record of successful international trainee education both in-country and at Northwestern, including support of 7 master's, 9 medium-term, and 223 short-term trainees. His expertise will be very helpful in planning a successful D43 proposal. AIIMS is India's premier medical research institute, and Dr. Tandon's appointments at both CCDC and the Department of Endocrinology and Metabolism at AIIMS will leverage his role as successful D43 PI with potential research trainees and infrastructure in New Delhi to create a competitive D43 application. Development of the research training components necessary to target these target areas (diverse faculty/trainee recruitment and retention, evaluation of appropriate didactic coursework, research project inventory, quality control/assurance training development, e.g.) will lead to a well thought-out D43 application in Year 2 of this D71 proposal between CCDC, Northwestern University, and AIIMS. The proposed D43 research training program will help fill key gaps in CCDC's current research capacity and further strengthen the collaboration between CCDC, Northwestern University, and AIIMS through the creation of a complementary, cross-connecting research program for Indian research trainees. Relevance Research capacity in advanced cardiovascular biostatistics, cardiovascular health and aging, and cardiovascular health policy modeling is lacking in India and in CCDC, in particular. As such, this proposal aims to strengthen the collaboration between CCDC, Northwestern, and AIIMS by creating an effective research training plan for a future D43 application in Year 2 to address these needs.

印度高级生物统计学、老龄化和卫生政策建模的心血管研究培训计划。 描述（由申请人提供）：拟议的申请旨在与美国芝加哥西北大学和印度新德里全印医学科学研究所（AIIMS）合作，为印度新德里慢性病控制中心（CCDC）未来的博士前和博士后研究员开发和完善研究培训计划活动，涉及3个目标领域：1）先进的心血管生物统计学，2）心血管健康和老龄化，3）心血管健康政策建模，以申请慢性，非传染性疾病和疾病在整个生命周期：福格蒂国际研究培训奖（NCD-LIFESPAN）（D43）在第二年。上述目标解决了CCDC的战略需求，并利用了CCDC、西北大学、AIIMS及其各自合作机构之间现有的成功合作。 CCDC是印度领先的非营利性研究机构，由D。Prabhakaran（当前D 71提案的首席研究员）。Prabhakaran博士是一名心脏病学家和流行病学家，拥有丰富的博士后研究培训经验，目前是NHLBI/UnitedHealth资助的位于新德里的全球卓越中心的首席研究员。他也是Fogarty国际临床研究学者和研究员计划的现场主任。在印度，心血管流行病学基金和研究的扩大并没有与生物统计学培训的相应扩大相匹配，随着CCDC领导或参与的许多大型流行病学研究的数据收集增加，这一差距将扩大。心血管健康和衰老方面的研究培训补充了CCDC目前的D43补助金（D43 PI：Nikhil Tandon [目前D 71提案的PD/PI联盟]），该项目侧重于早期生活事件在肥胖和糖尿病等慢性疾病发展中的作用。心血管健康和老龄化之间的关系是特别相关的，鉴于预测的人口结构在印度的转变。 心血管健康政策建模研究在包括印度在内的中低收入国家（LMIC）也很有限。虽然科学家呼吁循证决策，但缺乏心血管健康模型，可以在关键监测数据稀缺时为决策者提供指导。CCDC缺乏这三个目标领域的专业知识，博士前和博士后研究培训将满足这些需求。 西北大学预防医学系在这3个目标领域有着长期的研究和博士前和博士后研究培训记录，以帮助解决这些需求。西北大学还通过其正在进行的心血管流行病学T32培训资助（T32联合主任：Kiang Liu博士[当前D 71提案的联合研究员]）和LMIC研究员（刘博士）成功培训了来自美国的博士后研究员。CCDC和西北大学通过马克霍夫曼博士（合作者）福格蒂国际临床研究奖学金（共同导师，D。 Prabhakaran和Pand-Jones [目前D 71提案的PD/PI联盟]）和NIH K99/R 00资助。罗伯特·墨菲博士，西北大学全球健康中心主任，在全球健康培训方面拥有丰富的经验，担任两个NIH/Fogarty资助项目的PI：尼日利亚的医学教育伙伴关系倡议（MEPI）（包括负责研究行为培训的补充赠款），尼日利亚和马里的艾滋病国际培训和研究计划（AITRP）。Murphy博士在国内和西北大学都有成功的国际实习生教育记录，包括7名硕士，9名中期和223名短期实习生的支持。他的专业知识将非常有助于规划一个成功的D43提案。AIIMS是印度首屈一指的医学研究机构，Tandon博士在CCDC和AIIMS内分泌和代谢系的任命将利用他作为成功的D43 PI的角色，与潜在的研究学员和新德里的基础设施一起创建具有竞争力的D43应用程序。 开发针对这些目标领域所需的研究培训组件（例如，多样化的教师/学员招聘和保留，评估适当的教学课程，研究项目清单，质量控制/保证培训开发）将导致一个经过深思熟虑的D43申请在第二年的这个D 71之间的CCDC，西北大学和AIIMS的建议。拟议的D43研究培训计划将有助于填补CCDC目前研究能力的关键空白，并通过为印度研究学员创建互补的交叉连接研究计划，进一步加强CCDC，西北大学和AIIMS之间的合作。 相关性 在先进的心血管生物统计学，心血管健康和老龄化，心血管健康政策建模的研究能力是缺乏在印度和CCDC，特别是。因此，该提案旨在加强CCDC，西北大学和AIIMS之间的合作，为未来的D43申请制定有效的研究培训计划，以满足这些需求。