Point of Care Technology Research Center in Primary Care

描述(由申请人提供)：随着人口老龄化和慢性病负担的增加，初级保健提供者(PCP)的任务是提供日益复杂的护理。新兴的微流控、纳米技术和传感器小型化技术使开发用于初级保健的新一代护理点检测(POCT)系统成为可能，可以提高初级保健实践的效率。为了满足这一关键的国家需求，我们提议创建一个新的中心，将新兴的医疗保健点技术快速转化为商业上可行的、以临床为重点的解决方案，以改善初级卫生保健。我们打算利用和部署一种现有的、经过验证的方法来实现需求驱动型医疗保健技术创新，该方法由医学与创新技术集成中心(CIMIT)开创并验证了十多年，CIMIT是一个由大波士顿地区13家研究机构、大学和医院组成的老牌财团。我们的具体目标是： 1)应用CIMIT的创新模式，创建临床驱动型护理点解决方案，以解决初级保健领域中未得到满足的关键领域的需求，以及初级保健中未得到满足的需求。 2)确定和评估未得到满足的初级保健需求，并制定绩效标准，使护理点技术解决方案产生最大影响。 3)选择最有前景的护理点技术，并将其开发为概念验证原型。 4)相对于临床性能和实施标准，在模拟临床环境和临床“活实验室”中测试和评估原型性能。 5)将符合性能规格的原型转变为商业许可或初创公司的机会。 6)在创新过程中培训和教育相关利益攸关方--包括临床医生、工程师、科学家、学生和行业合作伙伴--以满足医疗保健需求。 7)与POCTRN其他中心合作，在国家和国际范围内传播创新方法和程序方面的“经验教训”和最佳做法。

DESCRIPTION (provided by applicant): Primary care providers (PCPs) are tasked with providing increasingly complex care as the population ages and the burden of chronic disease grows. Emerging microfluidic, nanotechnology and sensor miniaturization technologies are making it possible to develop a new generation of Point-of-Care test (POCT) systems for primary care that could improve efficiencies of primary care practices. To meet this critical national need, we propose to create a new center for rapid transformation of emerging point-of-care technologies into commercially viable, clinically-focused solutions for improving primary health care. We intend to leverage and deploy an existing, proven approach to needs-driven health care technology innovation pioneered and validated for more than a decade by the Center for Integration of Medicine and Innovative Technologies (CIMIT) - an established consortium of thirteen research institutions, universities and hospitals in the greater Boston area. Our specific aims are: 1) Apply CIMIT's innovation model to create clinically-driven point-of-care solutions that address critical areas of unmet need in primary healthcare areas of unmet need in primary healthcare. 2) Identify and assess unmet primary care needs and develop performance criteria where point-of-care technology solutions would have the highest impact. 3) Select the most promising point-of-care technologies and develop them into proof-of-concept prototypes. 4) Test and evaluate prototype performance in simulated clinical environments and clinical "living laboratories" relative to clinical performance and implementation criteria. 5) Transition prototypes that meet performance specifications into commercially licensable or start-up company opportunities. 6) Train and educate relevant stakeholders - including clinicians, engineers, scientists, students and industry partners - in the innovation process as it applies to meeting health care needs.. 7) Disseminate "lessons learned" and best practices in innovation methodology and process both nationally and internationally in collaboration with other POCTRN Centers.