Point of Care Technology Research Center in Primary Care

描述（由申请人提供）：随着人口老龄化和慢性病负担的增加，初级保健提供者（PCP）的任务是提供越来越复杂的护理。新兴的微流体、纳米技术和传感器微型化技术使开发新一代用于初级保健的即时检测（POCT）系统成为可能，这可以提高初级保健实践的效率。为了满足这一关键的国家需求，我们建议建立一个新的中心，将新兴的护理点技术快速转化为商业上可行的、以临床为重点的解决方案，以改善初级卫生保健。我们打算利用和部署现有的，经过验证的方法，以需求驱动的医疗技术创新，由医学和创新技术集成中心（CIMIT）开创和验证了十多年-一个由大波士顿地区的十三个研究机构，大学和医院组成的联盟。我们的具体目标是： 第一章 应用CIMIT的创新模式，创建临床驱动的床旁解决方案，解决初级医疗保健中未满足需求的关键领域。 （二） 识别和评估未满足的初级保健需求，并制定绩效标准，其中床旁技术解决方案将产生最大的影响。 第三章 选择最有前途的床旁技术，并将其开发成概念验证原型。 四、 在模拟临床环境和临床“生活实验室”中测试和评估原型性能，并与临床性能和实施标准相关。 第五章） 将符合性能规格的原型转化为商业许可或初创公司的机会。 六、 培训和教育相关利益相关者-包括临床医生，工程师，科学家，学生和行业合作伙伴-在创新过程中，因为它适用于满足医疗保健需求。 第七章） 与其他POCTRN中心合作，在国内和国际上传播创新方法和流程方面的“经验教训”和最佳做法。

DESCRIPTION (provided by applicant): Primary care providers (PCPs) are tasked with providing increasingly complex care as the population ages and the burden of chronic disease grows. Emerging microfluidic, nanotechnology and sensor miniaturization technologies are making it possible to develop a new generation of Point-of-Care test (POCT) systems for primary care that could improve efficiencies of primary care practices. To meet this critical national need, we propose to create a new center for rapid transformation of emerging point-of-care technologies into commercially viable, clinically-focused solutions for improving primary health care. We intend to leverage and deploy an existing, proven approach to needs-driven health care technology innovation pioneered and validated for more than a decade by the Center for Integration of Medicine and Innovative Technologies (CIMIT) - an established consortium of thirteen research institutions, universities and hospitals in the greater Boston area. Our specific aims are: 1) Apply CIMIT's innovation model to create clinically-driven point-of-care solutions that address critical areas of unmet need in primary healthcare areas of unmet need in primary healthcare. 2) Identify and assess unmet primary care needs and develop performance criteria where point-of-care technology solutions would have the highest impact. 3) Select the most promising point-of-care technologies and develop them into proof-of-concept prototypes. 4) Test and evaluate prototype performance in simulated clinical environments and clinical "living laboratories" relative to clinical performance and implementation criteria. 5) Transition prototypes that meet performance specifications into commercially licensable or start-up company opportunities. 6) Train and educate relevant stakeholders - including clinicians, engineers, scientists, students and industry partners - in the innovation process as it applies to meeting health care needs.. 7) Disseminate "lessons learned" and best practices in innovation methodology and process both nationally and internationally in collaboration with other POCTRN Centers.