Inhibition of Siderophore Biosynthesis for Tuberculosis Drug Discovery
Inhibition of Siderophore Biosynthesis for Tuberculosis Drug Discovery
批准号:
nhmrc : 632769
负责人:
Prof Richard Payne
金额:
$28.29万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Tuberculosis (TB) is responsible for over 2 million deaths globally every year. Despite this alarming statistic, no new TB drugs have reached the market in 40 years. This is despite the emergence of strains of Mycobacterium tuberculosis (the causative agent of TB) that are resistant to currently prescribed drugs. This project aims to discover TB drug leads with a unique mode of action. This will be achieved by preparing compounds that prevent the bacterium from acquiring iron from the host.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Greening the production of peptides and proteins
-
批准号:LP220100091
-
项目类别:Linkage Projects
-
资助金额:$32.64万
-
财政年份:2023
-
负责人:Prof Richard Payne
-
依托单位:
Site-specific protein functionalisation at diselenides via photocatalysis
-
批准号:DP230100186
-
项目类别:Discovery Projects
-
资助金额:$37.88万
-
财政年份:2023
-
负责人:Prof Richard Payne
-
依托单位:
Expanding access to modified proteins via a novel semi-synthetic platform
-
批准号:DP220101037
-
项目类别:Discovery Projects
-
资助金额:$36.03万
-
财政年份:2022
-
负责人:Prof Richard Payne
-
依托单位:
Australian Peptide Display Facility
-
批准号:LE220100060
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$51.52万
-
财政年份:2022
-
负责人:Prof Richard Payne
-
依托单位:
Functional studies of tyrosine sulfation using synthetic sulfoproteins
-
批准号:DP190101526
-
项目类别:Discovery Projects
-
资助金额:$38.56万
-
财政年份:2019
-
负责人:Prof Richard Payne
-
依托单位:
New South Wales molecular analysis platform: Fourier transform ion cyclotron resonance mass spectrometer and CHN&S analyser
-
批准号:LE180100050
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$49.62万
-
财政年份:2018
-
负责人:Prof Richard Payne
-
依托单位:
Development of Novel Anticoagulants Inspired by Nature for Improved Ischaemic Stroke Therapy
-
批准号:nhmrc : 1120941
-
项目类别:Project Grants
-
资助金额:$48.94万
-
财政年份:2017
-
负责人:Prof Richard Payne
-
依托单位:
Synthesis and Structure-Function Studies of the Glycoprotein Adiponectin
-
批准号:LP150100308
-
项目类别:Linkage Projects
-
资助金额:$21.23万
-
财政年份:2016
-
负责人:Prof Richard Payne
-
依托单位:
New peptide ligation technology for the rapid assembly of modified proteins
-
批准号:DP160101324
-
项目类别:Discovery Projects
-
资助金额:$31.72万
-
财政年份:2016
-
负责人:Prof Richard Payne
-
依托单位:
New platform technologies for the chemical synthesis of post-translationally modified proteins
-
批准号:FT130100150
-
项目类别:ARC Future Fellowships
-
资助金额:$60.86万
-
财政年份:2014
-
负责人:Prof Richard Payne
-
依托单位:
Development and application of new peptide ligation methods for the synthesis and structure-function studies of glycoproteins
-
批准号:DP130101984
-
项目类别:Discovery Projects
-
资助金额:$32.73万
-
财政年份:2013
-
负责人:Prof Richard Payne
-
依托单位:
A novel pathway for the regulation of vascular tone
-
批准号:nhmrc : 1020400
-
项目类别:Project Grants
-
资助金额:$39.78万
-
财政年份:2012
-
负责人:Prof Richard Payne
-
依托单位:
New methods for the chemical synthesis of a library of glycopeptide-based tri-component cancer vaccines
-
批准号:DP120100194
-
项目类别:Discovery Projects
-
资助金额:$30.13万
-
财政年份:2012
-
负责人:Prof Richard Payne
-
依托单位:
Solid-phase synthesis of sulfopeptides for evaluation of chemokine-receptor recognition
-
批准号:DP1094884
-
项目类别:Discovery Projects
-
资助金额:$33.44万
-
财政年份:2010
-
负责人:Prof Richard Payne
-
依托单位:
Chemical synthesis of cancer-associated glycoproteins
-
批准号:DP0986632
-
项目类别:Discovery Projects
-
资助金额:$33.63万
-
财政年份:2009
-
负责人:Prof Richard Payne
-
依托单位:
国内基金
海外基金
深海来源微生物中Siderophore类化合物的发掘及生物合成研究
-
批准号:81773628
-
项目类别:面上项目
-
资助金额:48.0万元
-
批准年份:2017
-
负责人:王鸿
-
依托单位:
云南特殊碱性环境真菌Siderophore结构多样性及其生物学功能考察
-
批准号:31260012
-
项目类别:地区科学基金项目
-
资助金额:58.0万元
-
批准年份:2012
-
负责人:李铭刚
-
依托单位:
新型海洋细菌中铁载体siderophore活性物质的研究
-
批准号:30472069
-
项目类别:面上项目
-
资助金额:22.0万元
-
批准年份:2004
-
负责人:张惠平
-
依托单位: