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Basic/Translational Research Training for CHP Pediatric Fellows

Basic/Translational Research Training for CHP Pediatric Fellows
卫生防护中心儿科研究员基础/转化研究培训
批准号:
8467258
负责人:
David H Perlmutter
金额:
$20.21万
依托单位国家:
美国
项目类别:
财政年份:
2013
资助国家:
美国
项目状态:
已结题
起止时间:
2013-05-01 至 2018-04-30

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中文摘要
翻译
描述(由申请人提供):这是一个应用程序,以重新建立一个指导培训计划的儿科亚专业研究员有兴趣在研究生涯涉及基础或转化研究。该计划提供了一个为期2年的经验,致力于培训细胞/分子生物学或转化研究,是有关儿童健康的4名研究员,每 为期一年,旨在开启职业生涯,最终成为NIH R 01资助的儿科医生科学家。该计划的主要特点之一是,它可用于匹兹堡大学儿科系内一些不具有T32补助金的子专业的研究员培训(过敏/免疫学;心脏病学;遗传学;血液学/肿瘤学;传染病;新生儿医学;肺病)。因此,它可以通过瞄准最有才华的研究员并将他们与优秀的导师配对来最大限度地获得校外支持。指导教师包括25名杰出的研究人员,他们在研究贡献和指导方面有着杰出的记录。这种指导经验的哲学重点是科学方法的基础知识与严谨和诚信的最高标准相结合,因为我们相信这些是最有可能导致长期成功职业生涯的培训经验的特点。申请K 08、K23或K99/R 00补助金。皮特的儿科系拥有全国发展最快的儿科研究项目之一,并以UPMC校园匹兹堡新儿童医院为基础,新的30万平方英尺的CHP Rangos儿科研究大楼。基于这些特点和我们以前的培训结果,我们相信,该计划提供了一个强大的导师团队和智力丰富的环境,将激励儿科专科研究员,并为他们提供背景,成为成功的儿童健康研究人员。
英文摘要
DESCRIPTION (provided by applicant): This is an application to re-establish a mentored training program for pediatric subspecialty fellows interested in research careers involving basic or translational research. The program offers a 2-year experience dedicated to training in cell/molecular biology or translational research that is relevant to child health for 4 fellows per year and is designed to serve as a launch for a career that ultimately as an NIH R01-funded pediatric physician scientist. One of the key features of this program is that is can be used for training of fellows in a number of subspecialties within the Department of Pediatrics of the University of Pittsburgh that do not have a T32 grant (Allergy/Immunology; Cardiology; Genetics; Hematology/Oncology; Infectious Diseases; Newborn Medicine; Pulmonology). Thus, it can maximize the extramural support by targeting the most talented fellows and matching them with outstanding mentors. The mentoring faculty includes 25 outstanding researchers who have a distinguished record of research contributions and mentoring. The philosophical emphasis of this mentoring experience is fundamentals of the scientific method combined with the highest standard of excellence for rigor and integrity because we believe these are the characteristics of the training experience that are most likely to lead to a long successful career Each of the Scholars is expected to carry out a challenging research project in the laboratory of one of the faculty mentors leading to publications as well as an application for their own K08, K23 or K99/R00 grant. The Department of Pediatrics at Pitt has one of the fastest growing pediatric research programs in the country and is based on a new Children's Hospital of Pittsburgh of UPMC campus with the new 300,000-square-foot CHP Rangos Pediatric Research Building. Based on these characteristics and our previous training results, we believe that this program provides a powerful team of mentors and intellectually-rich environment that will inspire pediatric subspecialty fellows and provide them with the background to become successful child health researchers.
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Novel therapies that target mitochondrial dysfunction for treatment of a1-antitrypsin deficiency liver disease
  • 批准号:
    10342938
  • 项目类别:
  • 资助金额:
    $66.31万
  • 财政年份:
    2021
  • 负责人:
    David H Perlmutter
  • 依托单位:
Novel therapies that target mitochondrial dysfunction for treatment of a1-antitrypsin deficiency liver disease
  • 批准号:
    10541910
  • 项目类别:
  • 资助金额:
    $62.36万
  • 财政年份:
    2021
  • 负责人:
    David H Perlmutter
  • 依托单位:
Signaling Pathways Influencing Liver Disease Phenotype in Antitrypsin Deficiency
  • 批准号:
    9180521
  • 项目类别:
  • 资助金额:
    $46.08万
  • 财政年份:
    2016
  • 负责人:
    David H Perlmutter
  • 依托单位:
Signaling Pathways Influencing Liver Disease Phenotype in Antitrypsin Deficiency
  • 批准号:
    9251285
  • 项目类别:
  • 资助金额:
    $45.24万
  • 财政年份:
    2016
  • 负责人:
    David H Perlmutter
  • 依托单位:
海外基金