Tagging of Histopathology Specimens with Light-Activated RFID p-Chips

使用光激活 RFID p 芯片标记组织病理学样本

• 批准号: 8542871
• 负责人: WLODEK MANDECKI
• 金额: $ 59.25万
• 依托单位: PHARMASEQ, INC.
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-02-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8542871
• 关键词: Adherence; Adhesives; Adoption; Amplifiers; Appearance; Area; Benchmarking; Charge; Chemicals; Clinical Trials; Communication; Computer software; Computers; Contractor; Custom; Databases; Diagnostic; Docking; Electronics; Epoxy Compounds; Evaluation; Feedback; Frequencies; Glass; Goals; Hand; Histopathology; Hospitals; Human Resources; Hybrids; Institution; Label; Laboratories; Lasers; Light; Link; Liquid substance; Maintenance; Manufacturer Name; Mechanics; Medical; Medical Research; Methods; Molds; Noise; Optics; Pathology; Performance; Play; Polypropylenes; Printing; Process; Protocols documentation; Provider; Readability; Reader; Reading; Research; Retrieval; Robot; Robotics; Role; Sampling; Scanning; Side; Signal Transduction; Silicon; Slide; Solutions; Solvents; Source; Specimen; System; Systems Development; Technology; Temperature; Testing; Texas; Tissue Sample; Tissue Stains; Tissues; Update; Validation; Wireless Technology; Work; anticancer research; base; chemical stability; cost; design; drug discovery; improved; instrument; knowledge base; lens; programs; prototype; validation studies

DESCRIPTION (provided by applicant): The purpose of the present project is to develop and validate the use of ultra-small RFID chips to tag and track tissue cassettes and glass slides that are used in histopathology laboratories. The system is based on the PharmaSeq laser light-activated microtransponder, also known as "p-Chip". The chip's major advantages are its small size (500 ¿m x 500 ¿m x 100 ¿m), unitary design, inertness, ease of use and very low cost. The system consists of the p-Chip-tagged glass slides and tissue cassettes, a stationary reader, a portable reader for trays with slides, and associated software that allows integration with common database software. The main goals of the project are to: 1) develop semi-automated methods of attaching p-Chips to slides and cassettes, 2) build advanced prototypes of the ID reader (wand) and improve key features, such as the form factors for reading each type of container, 3) improve the design of the p-Chip to increase the read range and refine methods of their post-fabrication processing, and 4) conduct extensive pilot test studies with outside collaborators to validate the system. The ID readers will have a modified optical system and will feature wireless communication between the reader and a workstation or central computer. The adoption of the system will improve reliability for tagging and tracking tissue samples.

描述(由申请人提供)：本项目的目的是开发和验证超小型RFID芯片的使用，以标记和跟踪组织病理学实验室中使用的组织盒和玻璃片。该系统基于PharmaSeq激光光控微应答器，也被称为“p-Chip”。该芯片的主要优势是体积小(500？m x 500？m x 100？m)、设计统一、惰性、使用方便且成本非常低。该系统包括贴有P-Chip标签的玻璃片和纸盒、一个固定式阅读器、一个装有幻灯片的托盘的便携式阅读器，以及允许与通用数据库软件集成的相关软件。该项目的主要目标是：1)开发将P芯片安装到幻灯片和磁带上的半自动方法；2)建立先进的ID读取器(棒)的原型，并改进关键功能，如读取每种类型容器的形状系数；3)改进P芯片的设计，以增加读取范围并改进其制造后处理方法；以及4)与外部合作者进行广泛的试验性测试研究，以验证系统。身份证阅读器将有一个改装的光学系统，并将具有阅读器与工作站或中央计算机之间的无线通信功能。该系统的采用将提高标记和跟踪组织样本的可靠性。