Multiplexed Protein Assays
Multiplexed Protein Assays
批准号:
8648596
负责人:
MARK S. CHEE
金额:
$35.0万
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-04-15 至 2016-02-29
关键词:
AddressAntibodiesAtlasesBiological AssayBrainCellsCommunicationComplexCoupledDNADataDetectionDevelopmentDiagnosticDiagnostics ResearchDiseaseFluorescenceFormalinGene ProteinsGenerationsGenesGenetic TranscriptionHistologyHumanImageImmunohistochemistryIn SituIndividualLabelLocationMalignant NeoplasmsMapsMessenger RNAMethodsMolecularMorphologyNucleic AcidsOperating SystemOrganParaffin EmbeddingPatternPeptide Signal SequencesPhaseProtein AnalysisProteinsProteomePublishingRNARegulationResearch PersonnelResolutionSamplingSchemeSignal TransductionSiteSpecificitySystemTechniquesTechnologyTestingTherapeuticTimeTissue MicroarrayTissue SampleTissuesTranslatingWorkantibody conjugatebiological systemsbrain tissuecell typecomplex biological systemsdesignfluorescence imaginghigh throughput technologyinsightlaser capture microdissectionnew technologynovelprognosticprotein expressionpublic health relevance
中文摘要
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英文摘要
SUMMARY
New technologies are needed to enable the multiplexed analysis of proteins. Our aim is to develop a highly
parallel assay technology for obtaining information on protein abundance. This would enable the generation of
high-resolution maps of the proteome of complex tissues, and assist in the detection of protein interactions.
The technology is designed for analyzing complex and dynamic biological systems, including regulatory and
communication systems that operate at the cellular and multicellular level.
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