预防艾滋病毒的男性互联网研究 III (MINTS-III)-猫眼课题宝

预防艾滋病毒的男性互联网研究 III (MINTS-III)

批准号：

8644889

负责人：

B R Simon Rosser

金额：

$57.79万

依托单位：

UNIVERSITY OF MINNESOTA

依托单位国家：

美国

项目类别：

财政年份：

2010

资助国家：

美国

项目状态：

已结题

起止时间：

2010-09-22 至 2017-03-31

来源：

https://reporter.nih.gov/project-details/8644889

关键词：

AIDS prevention Affect Anus Area Awareness Behavioral Build-it Cognitive Computers Control Groups Data Deception Effectiveness Effectiveness of Interventions Ensure Ethnic Origin Feedback Funding Game Theory HIV HIV risk Health Health Services Individual Information Technology Internet Intervention Interview Knowledge Latino Length Measurement Measures Mediation Methods Needs Assessment Noise Outcome Participant Population Positioning Attribute Prevention Research Prevention approach Preventive Intervention Process Productivity Progress Reports Public Health Publications Race Recruitment Activity Reporting Research Respondent Risk Risk Assessment Risk Behaviors Risk Reduction Science Self Efficacy Self-control as a personality trait Sexual Health Social Desirability Social support Stress Surveys Tail Targeted Research Technology Telephone Testing Time Treatment Efficacy United States National Institutes of Health Validity and Reliability Variant arm base conditioning condoms design dosage effective intervention experience follow-up group intervention high risk high risk behavior high risk men high risk sexual behavior improved innovation instrument male men men who have sex with men novel strategies post intervention protective efficacy public health relevance response service intervention sex sex risk skills social theories usability user centered design

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DESCRIPTION (provided by applicant): MINTS-III is a competing continuation application resubmission in response to PA-07-295. It builds upon MINTS-I, one of the first survey studies of the Internet and HIV risk among MSM; and MINTS-II, which developed and tested Sexpulse, an online, HIV prevention intervention for Men who use the Internet to seek Sex with Men (MISM). MINTS-II is the first online RCT of MISM to report acceptable retention over 12 months and short-term efficacy. At the 3-month follow-up, the intervention group reported a significantly greater (20%) reduction in risk behavior than the null control. We also observed a significant reduction in reported risk behavior in the control group, which we hypothesize is the product of panel conditioning. MINTS-III is the logical next step in this promising area of research. Our first aim is to increase the long-term HIV prevention effectiveness of the intervention by strengthening the dosage of Sexpulse. A substantial user-centered design iteration of the intervention will incorporate personalized, tailored feedback on individual risk behavior; integrate research surveys into the intervention; and add follow-up boosters all aimed at increasing the long-term behavioral effectiveness. In Aim 2, we propose two sub-studies to examine the reliability and validity of online measures of sexual risk behavior. Aim 3 tests the long-term risk reduction efficacy of the strengthened intervention, Sexpulse 1.1, and boosters, in an RCT of 1000 high-risk MISM. This RCT design has been enhanced by three levels of recruitment so that in Aim 4, we can study threats to risk measurement, especially panel conditioning. Our final aim tests the long-term protective efficacy of Sexpulse 1.1 (including online boosters) in an RCT on 500 no/lower risk MISM. Upon successful completion of these aims, Sexpulse 1.1 should be a strong and demonstrated-effective intervention that can be strategically positioned for dissemination.

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