Fetal Magnetocardiography Using Non-cryogenic Magnetic Field Sensors

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DESCRIPTION (provided by applicant): While the number of diagnostic technologies available for adult applications continues to grow, there remains a paucity of technologies suitable for fetal evaluation. In particular, noninvasive assessment of fetal cardiac electrophysiology has not been routinely possible despite many decades of fetal ECG research. Recently, a number of groups have demonstrated the efficacy of fetal magnetocardiography (fMCG), the magnetic analog of fetal ECG, as a new method of assessing fetal heart rate, rhythm, and conduction. The last few years have seen rapid progress in demonstrating the diagnostic efficacy of fMCG, as well as in magnetometer technology. The goal of this project is to reduce the price of a complete fetal MCG system from approximately $1M at present to below $100k. The system we propose to develop is based on new low-cost, room-temperature atomic magnetometers that are just as sensitive as existing superconducting magnetometers. During Phase I we established the feasibility of our approach through independent evaluation in a clinical environment. During Phase II we will develop a full-scale, turn-key system that is ready for commercialization.