2015 Parkinson's Disease Gordon Research Conference

2015年帕金森病戈登研究会议

• 批准号: 8835619
• 负责人: David Sulzer
• 金额: $ 2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-30 至 2015-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8835619
• 关键词: Address; Age; Area; Asia; Basic Science; Cellular biology; Cessation of life; Collaborations; Communities; Data; Disease; Enrollment; Environment; Ethnic Origin; Etiology; Europe; Event; Faculty; Fostering; Future; Gender; Genes; Genetic; Geographic Locations; Goals; Institution; International; Ion Channel; Knowledge; Lead; Lewy Body Disease; Maps; Minority; Movement Disorders; Neurodegenerative Disorders; Neurologic; Neurons; Neurosciences; North America; Parkinson Disease; Participant; Pathogenesis; Patients; Postdoctoral Fellow; Process; Research; Research Personnel; Role; Schedule; Scientist; Series; Site; Staging; Students; Technology; Testing; Time; United States National Institutes of Health; Weather; Woman; Work; abstracting; base; career; college; cost; design; disease-causing mutation; endoplasmic reticulum stress; insight; interest; meetings; motor disorder; posters; prevent; prion-like; programs; protein aggregate; public health relevance; response; social; symposium

 DESCRIPTION (provided by applicant): Parkinson's disease (PD) is the most common motor disorder. Over the past fifteen years, the discovery of disease-causing mutations in a growing number of genes has accelerated the pace of our understanding of disease mechanisms. Simultaneous discoveries in cell biology and immunological processes related to the genetic discoveries are rapidly providing insights into the processes that lead to this disease. This creates an exciting series of challenges and opportunities to be addressed by the discussion and exchange of ideas. There has, to our knowledge, never been a basic research conference devoted to PD, and this conference will bring together investigators with diverse scientific backgrounds who share an interest in cellular mechanisms that produce PD and its related disorders. The inaugural PD GRC meeting will be held June 28-July 3, 2015 at Colby Sawyer College and is intended to recur biennially. The specific content of the Conference will evolve as our understanding of PD evolves: the first conference will in particular address pathogenic steps that may underlie the disease and its accompanying neuronal death. The long-term objective will be to create a means to share ideas and data on the cause and treatment of Parkinson's disease and related disorders, and the specific areas of concentration will change with new scientific insights. This meeting, by bringing together scientists with different knowledge, opinions, and technical approaches, will serve to develop new therapies for millions of patients of PD and related disorders including Lewy body diseases and other movement disorders. The enrollment for this inaugural meeting is expected to be 178, the limit at Colby Sawyer College. The NIH is being asked to help cover the registration costs for 48 early career investigators. These investigators will be chosen from the invited speakers and those with outstanding poster abstracts. If the meeting is deemed successful by attendees, the Gordon Conference administration, and the NIH, it can be continued and expanded on a biennial basis. We have designed a highly interactive format that fosters discussion of cutting-edge unpublished results and supports meaningful dialog of controversies and needs in the field. The well-tested GRC format creates a unique opportunity for students, post-doctoral fellows and faculty to interact regardless of professional status and gain a deeper understanding of fundamental questions facing the field or PD and movement disorders and to build cross-cutting collaborations that could lead to breakthroughs. We further intend to promote participant diversity by providing attendance and participation by women, minorities, and scientists from a variety of backgrounds, including those that work at academic and commercial institutions.

 描述（由适用提供）：帕金森氏病（PD）是最常见的运动障碍。在过去的十五年中，越来越多的基因中发现引起疾病的突变的发现加速了我们对疾病机制的理解。与遗传发现有关的细胞生物学和免疫过程的同时发现正在迅速提供有关导致该疾病的过程的见解。这创造了一系列令人兴奋的挑战和机会，以解决思想的讨论和交流。据我们所知，从来没有参加过专门针对PD的基础研究会议，该会议将把具有多种科学背景的调查员聚集在一起，他们对产生PD及其相关疾病的蜂窝机制具有兴趣。首届PD GRC会议将于2015年6月28日至7月3日在Colby Sawyer College举行，并旨在重复两年一度。会议的具体内容将随着我们对PD的理解的发展而发展：第一次会议将特别解决可能是该疾病及其涉及神经元死亡的致病步骤。长期目标是创建一种分享有关帕金森氏病和相关疾病的原因和治疗的想法和数据的方法，而集中的特定领域将随着新的科学见解而改变。通过将具有不同知识，观点和技术方法的科学家汇集在一起​​，将为数百万个PD患者和相关疾病（包括Lewy身体疾病和其他运动障碍）开发新的疗法。这次就职会议的入学率预计为178，是科尔比·索耶学院的极限。 NIH被要求帮助支付48名早期职业调查人员的注册费用。这些调查人员将从受邀演讲者和具有出色海报摘要的人中选择。如果会议被参与者，戈登会议管理局和NIH认为成功，则可以在两年前进行并扩大。我们设计了一种高度互动的格式，该格式促进了对尖端未发表的结果的讨论，并支持了该领域中争议和需求的有意义的对话。经过良好测试的GRC格式为学生，博士后研究员和教师创造了独特的机会，无论专业地位如何，都可以更深入地了解领域或PD和运动障碍面临的基本问题，并建立跨裁切协作，从而导致突破。我们进一步打算通过提供来自各种背景的妇女，少数民族和科学家的出席和参与，包括在学术和商业机构工作的妇女，少数民族和科学家的参与。