Administrative Core

在过去的十年中，俄克拉荷马州COBRE GM 103456（以前的RR 020143）"分子机制和 自身免疫遗传学"已经成为改变俄克拉荷马州医学研究的关键资源 基金会成为一个致力于指导和发展初级调查员的机构， 富有成效的独立科学事业，重点是自身免疫性疾病的遗传学。 通过对11名初级调查员、16个试点项目和一套不断发展的3 - 4名核心人员的支助， 资源提供了基础设施，以帮助启动11个独立的研究事业，并支持 随后由其他NIH研究所资助的许多多研究者资助（“项目资助”）。 我们的行政核心将作为COBRE的集中管理资源， 行政协助和监督的研究和试点核心，并作为联络员之间的 指导委员会、外部咨询委员会、机构行政部门和COBRE调查员。的 COBRE继续的科学战略目的是支持遗传学研究， 自身免疫性疾病的基因组学，并开始扩大我们的范围COBRE调查其他 包括癌症、心血管疾病和罕见疾病在内的学科。的具体目标 管理的核心是1）对财务独立研究进行协调、整合和财务管理 核心，满足和扩展我们的COBRE调查员的科学机会，2）评估和 管理研究核心和试点项目的有效性，3）实施和扩大多学科 丰富的方案，4）协助赠款申请，管理和合规问题。

For the past decade, the Oklahoma COBRE GM103456 (previously RR020143) "Molecular Mechanisms and Genetics of Autoimmunity" has been a pivotal resource in transforming the Oklahoma Medical Research Foundation into an institution committed to the mentoring and development of junior investigators to productive independent scientific careers with an emphasis on the genetics of autoimmune diseases. Through its support of 11 junior investigators, 16 pilot projects, and an evolving set of 3-4 cores, this resource has provided the infrastructure to help launch 11 independent research careers and support the subsequent funding of numerous multi-investigator grants ("program grants") funded by other NIH institutes. Our Administrative Core will serve as a centralized governing resource for the COBRE, provide adminitstrative assistance and oversight to the research and Pilot cores and serve as a liason between the steering committee, external advisory committee, institutional administration and COBRE investigators. The scientific strategic purpose of the continuation of this COBRE is to support research in the genetics and genomics of autoimmune diseases and begin to broaden our scope of COBRE investigators to other disciplines including cancer, cardiovascular diseases and rare disorders. The Specific Aims ofthe Administrative core are to 1) coordinate, integrate and fiscally manage to financial independence research cores, which meet and extend the scientific opportunities of our COBRE Investigators, 2) evaluate and manage the effectiveness of research cores and pilot projects, 3) implement and expand multidisciplinary enrichment programs and, 4) assist with grant applications, management and compliance issues.