Pediatric Infectious Diseases and Immunity Training Program

描述（由申请人提供）：我们提出了一个博士后培训计划，在儿科感染性疾病和免疫（PIDI-TP）的基础上，在华盛顿大学（WU）/圣路易斯儿童医院儿科感染性疾病部门。长期目标是培养学术医生-科学家，以开展儿科传染病研究，包括宿主对感染的反应。吴医学中心提供了一个优秀的培训环境，为医生，科学家与国家认可的医院与全国首屈一指的生物医学研究设施之一。华盛顿大学的许多教员都是传染病和人类免疫学的主要研究人员。PIDI-TP还将利用WU基因组研究所的优势，WU基因组研究所是世界上最先进的基因组测序中心之一，在人类微生物组计划中发挥了主导作用。PIDI-TP导师，来自儿科，医学，病理学和免疫学，分子微生物学的WU部门是非常成功的调查人员，具有独立的研究计划和指导医生科学家的经验。PIDI-TP项目主任将是儿科教授兼儿科传染病科主任Gregory Storch。联合项目主任将是病理学和免疫学副教授Thad Stappenbeck。一个咨询委员会由三名高级吴教师和一名杰出的外部成员将建议PD和共同PD。执行委员会将监督受训人员的招聘和甄选，监测受训人员的业绩和职业发展，并评估方案的运作和成果。学员还将向奖学金监督委员会报告，其调查结果将由PD，共同PD和执行委员会审查。每年需要两名学员的支持，从传染病、风湿病、新生儿病学、过敏/肺/免疫学、肾脏病学和重症监护的儿科奖学金项目以及圣路易斯儿童医院的住院医师中招募，特别是那些拥有医学博士和博士学位的人。这批申请人足以填补所要求的职位。学员将被分配到三个轨道之一：“病原体”，“主机”和“基因组学/微生物组/病原体发现”。每个PIDI-TP受训者将在项目导师的监督下拥有主要的研究经验。核心课程将提供研究设计，生物统计学，研究伦理，人类受试者，动物受试者，科学写作，赠款准备和基因组学方面的培训，并将通过个性化课程进行补充，具体针对受训者选择的轨道。受训人员还将在职业规划和准备专科委员会考试方面得到帮助。职业发展将由研究导师，PD和共同PD，执行委员会和SOC监测。计划评估将包括短期和长期指标，以及当前和过去受训人员的投入。将努力加强学员和导师的多样性。

DESCRIPTION (provided by applicant): We propose a post-doctoral training program in pediatric infectious diseases and immunity (PIDI-TP) based in the Pediatric Infectious Diseases Division of Washington University (WU)/St. Louis Children's Hospital. The long-term objective is to train academic physician-scientists to carry out research in pediatric infectious diseases including host response to infections. WU Medical Center offers an outstanding training environment for physician-scientists with nationally recognized hospitals conjoined with one of the nation's premier biomedical research facilities. Many Washington University faculty members are leading investigators in infectious diseases and human immunology. PIDI-TP will also take advantage of the WU Genome Institute, one of the world's most advanced genome sequencing centers that has played a leading role in the Human Microbiome Project. PIDI-TP mentors, drawn from the WU Departments of Pediatrics, Medicine, Pathology & Immunology, and Molecular Microbiology are highly successful investigators with independent research programs and experience in mentoring physician-scientists. The PIDI-TP Program Director will be Gregory Storch, Professor of Pediatrics and Director of the Division of Pediatric Infectious Diseases. The co-Program Director will be Thad Stappenbeck, Associate Professor of Pathology & Immunology. An Advisory Committee consisting of three senior WU faculty members and one distinguished outside member will advise the PD and co-PD. An Executive Committee will oversee recruitment and selection of trainees, monitor the performance and career development of trainees, and evaluate program operations and outcomes. Trainees will also report to Scholarship Oversight Committees, whose findings will be reviewed by the PD, co-PD, and Executive Committee. Support is requested for two trainees per year, to be recruited from pediatric fellowship programs in Infectious Diseases, Rheumatology, Neonatology, Allergy/Pulmonary/Immunology, Nephrology, and Critical Care, and from residents at St. Louis Children's Hospital, especially those with MD and PhD degrees. This pool of applicants is sufficient to fill the positions requested. Trainees will be assigned to one of three tracks: "Pathogens", "Host", and "Genomics/Microbiome/Pathogen Discovery". Each PIDI-TP trainee will have a major research experience under the supervision of a program mentor. A Core Curriculum will provide training in study design, biostatistics, research ethics, human subjects, animal subjects, scientific writing, preparation of grants, and genomics, and will be supplemented by an individualized curriculum, specific for the trainee's chosen track. Trainees will also receive assistance in career planning and in preparation for subspecialty Board examinations. Career development will be monitored by research mentors, the PD and co-PD, the Executive Committee and the SOCs. Program evaluation will include short-term and long-term metrics plus input from current and past trainees. Efforts will be made to enhance diversity of trainees and mentors.