Research Training in Global Non-Communicable Diseases

项目总结 非传染性疾病占全球所有死亡人数的71%。然而，研究的培训机会 全球心血管疾病、心脏代谢疾病、肺病和血液病是有限的。关键问题 包括了解改善健康和减少疾病的最佳治疗和实施方案， 不同人群在病理生物学和治疗反应方面的关键差异，以及相关的环境和 影响全球疾病发展的社会行为因素。在这项提案中开发的计划， 全球非传染性疾病研究培训，旨在为博士后提供 马萨诸塞州综合医院(MGH)有出色的机会获得研究技能和高 高质量的指导，为解决全球心血管、心脏代谢、 肺病和血液病。培训方案中研究员的主要活动包括 临床有效性(专门为博士后医生设计的严格的暑期计划)和其他 哈佛大学公共卫生学院与全球卫生相关的课程。我们还将指示 全球卫生研究实施和管理以及职业发展研究员，通过 MGH临床研究部以计划为基础的研讨会和课程。其他专业人员 发展资源将通过多项以MGH为基础的倡议和哈佛大学促进会提供。这个 拟议的方案还将支持实践共同体，以促进研究员之间的联系，他们的 导师和其他全球健康研究人员的专业发展和健康。此外， 为研究员提供的忠诚和有才华的导师团队将接受高级导师培训 以优化支持研究员的有效性。重要的是，该计划将努力实现 并促进全球卫生伙伴关系内的公平。我们的目标是： 1.在高影响力的全球心血管和心脏代谢健康研究方面提供指导研究， 肺病和血液病将培养下一代全球卫生研究人员 2.通过课程作业和研讨会开展研究培训，并通过 全球卫生研究人员的执业模式 3.培训导师，以优化在全球卫生研究领域工作的受训人员的成功。 全球非传染性疾病研究培训计划将总共支持8名研究员 (每年两次)，每个人都接受两年的研究支持、教学培训和高强度的、有目的的 研究和职业指导。该计划旨在为所有研究员的研究生涯做好准备，包括 职业发展和向国家卫生研究院资助的独立研究过渡。该计划的影响将是 通过导师的质量以及研究员的生产力和进步来衡量。

PROJECT SUMMARY Non-communicable diseases account for 71% of all deaths globally. Yet, training opportunities for research in global cardiovascular, cardiometabolic, pulmonary, and hematologic diseases are limited. Critical questions involve understanding optimal treatment and implementation programs to improve health and reduce disease, key differences among populations in pathobiology and treatment responses, and relevant environmental and socio-behavioral factors that influence disease progression globally. The program developed in this proposal, Research Training in Global Non-Communicable Diseases, is designed to provide post-doctoral fellows at Massachusetts General Hospital (MGH) with outstanding opportunities to obtain research skills and high- quality mentorship to prepare for research careers addressing global cardiovascular, cardiometabolic, pulmonary, and hematologic diseases. Key activities for fellows in the training program include the Program in Clinical Effectiveness (a rigorous summer program designed explicitly for postdoctoral physicians) and other coursework relevant for global health at the Harvard T.H. Chan School of Public Health. We will also instruct fellows on global health research implementation and administration as well as career development through program-based seminars and courses in the MGH Division of Clinical Research. Additional professional development resources will be available through multiple MGH-based initiatives and the Harvard Catalyst. The proposed program will also support a Community of Practice to promote connections among the fellows, their mentors, and other global health researchers for professional development and wellness. Additionally, the committed and talented group of mentors available to the fellows will receive advanced training in mentorship to optimize the effectiveness in supporting the fellows. Importantly, the program will strive for diversity among its fellows and promote equity within global health partnerships. Our aims are as follows: 1. Provide mentored research in high-impact global health research of cardiovascular and cardiometabolic, pulmonary, and hematologic diseases to develop the next generation of global health investigators 2. Conduct research training through coursework and seminars that is enriched through a Community of Practice model among global health investigators 3. Train mentors to optimize the success of supported trainees working in global health research. The Research Training in Global Non-Communicable Diseases Program will support a total of eight fellows (two per year), each receiving two years of research support, didactic training, and intense and purposeful research and career mentorship. The program aims to prepare all fellows for research careers, including career development and transition to independent NIH-funded research. Impact of the program will be measured through the quality of mentorship, as well as the productivity and advancement of the fellows.