Systems Biology of Infectious Diseases: Pathogenesis to Personalized Medicine

传染病的系统生物学：个性化医疗的发病机制

• 批准号: 8789251
• 负责人: MICHAEL G KATZE
• 金额: $ 0.84万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8789251
• 关键词: Acquired Immunodeficiency Syndrome; Award; Bioinformatics; Caring; Collaborations; Committee Members; Communicable Diseases; Computational Biology; Development; Disease; Disease Outcome; Emerging Communicable Diseases; Environment; Family; Fostering; Funding; Future; Gender; Genetic; Genome; Goals; Individual; Infection; Infectious Diseases Research; Institutes; Investments; Learning; Mathematics; Medicine; Methods; Microbe; Minority; National Institute of Allergy and Infectious Disease; Oral; Participant; Pathogenesis; Patients; Postdoctoral Fellow; Process; Research; Research Personnel; Resources; Respiratory Tract Infections; Role; Science; Scientist; Services; System; Systems Biology; Technology; Travel; Tuberculosis; United States National Institutes of Health; Universities; Washington; abstracting; base; computer science; fighting; graduate student; interest; multidisciplinary; new technology; pandemic influenza; pathogen; posters; prevent; programs; public health relevance; response; symposium; systems research; technology development; web site

DESCRIPTION (provided by applicant): This conference will feature discussions on computational biology and bioinformatics, technology development, and the use of systems-level approaches in a wide range of infectious disease applications. We will highlight research aimed at understanding, treating, and preventing conditions such as AIDS, respiratory infections, and tuberculosis. We will also feature presentations on the identification of emerging pathogens, the role of host genetics in determining disease outcome, and the promises of personalized care. Our goal is to provide a unique opportunity for a multidisciplinary group of investigators to learn from each other, discuss how to exploit new resources and technologies, and decide where to focus future research and development efforts. The conference will also provide abundant opportunities for networking and for establishing new collaborations. To encourage interactions between attendees and with corporate sponsors, we will cap registration at 150 attendees. Attendance is open to all interested individuals, and registrations will be processed on a first-come basis. The conference will be held at the Orin Smith Conference Center located on the South Lake Union campus of the University of Washington. To encourage attendance by young scientists, we will make available a total of 10 travel awards to graduate students and postdoctoral fellows. Gender and minority representation, as well as scientific expertise and merit, have been considered during the process of choosing members of committees and speakers for the conference. Information regarding family care services will be posted on the conference website and will be included with the registration materials provided to attendees. The scientific program will consist of five oral sessions and a poster session. Oral sessions will include presentations by invited speakers and additional speakers chosen from submitted abstracts. At the end of selected sessions, there will be a round-table discussion to promote exchanges between presenters and conference participants and to focus on important or controversial issues that relate to themes in the respective session. Ongoing advances in genome science, technology, and computation create a rapidly changing research environment that makes this conference timely, significant, and exciting. Our goal is to facilitate the exchang of information in this rapidly growing field and to help define future directions for incorporating systems biology approaches into translational and infectious disease research.

描述（由申请人提供）：本次会议将重点讨论计算生物学和生物信息学、技术开发以及系统级方法在广泛的传染病应用中的使用。我们将重点关注旨在了解、治疗和预防艾滋病、呼吸道感染和结核病等疾病的研究。我们还将介绍新出现的病原体的识别、宿主遗传学在确定疾病结果中的作用以及个性化护理的前景。我们的目标是为多学科研究人员小组提供一个独特的机会，让他们互相学习，讨论如何利用新资源和技术，并决定未来研究和开发工作的重点。会议还将提供丰富的交流和建立新合作的机会。为了鼓励与会者之间以及与企业赞助商之间的互动，我们将注册人数上限限制为 150 名与会者。所有感兴趣的个人均可参加，注册将按照先到先得的原则进行。会议将在位于华盛顿大学南湖联合校区的奥林·史密斯会议中心举行。为了鼓励年轻科学家参加，我们将为研究生和博士后提供总共10个旅行奖励。在选择会议委员会成员和发言人的过程中，考虑了性别和少数群体的代表性以及科学专业知识和优点。有关家庭护理服务的信息将发布在会议网站上，并将包含在提供给与会者的注册材料中。科学计划将包括五次口头会议和一次海报会议。口头会议将包括受邀演讲者和从提交的摘要中选出的其他演讲者的演讲。在选定的会议结束时，将举行圆桌讨论，以促进演讲者和与会者之间的交流，并重点讨论与各会议主题相关的重要或有争议的问题。基因组科学、技术和计算的不断进步创造了一个快速变化的研究环境，使这次会议变得及时、重要和令人兴奋。我们的目标是促进这个快速发展领域的信息交流，并帮助确定未来的整合方向 系统生物学方法进入转化和传染病研究。

项目成果

A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm.

• DOI: 10.1128/mbio.00325-10
• 发表时间: 2011-03-01
• 期刊: mBio
• 影响因子: 6.4
• 作者: Aderem A;Adkins JN;Ansong C;Galagan J;Kaiser S;Korth MJ;Law GL;McDermott JG;Proll SC;Rosenberger C;Schoolnik G;Katze MG
• 通讯作者: Katze MG