Environmental Toxicology and Epidemiology Pre/Post Doctoral Research Training

环境毒理学和流行病学博士前/后研究培训

• 批准号: 8855397
• 负责人: Rita K Loch-Caruso
• 金额: $ 39.01万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1979
• 资助国家: 美国
• 起止时间: 1979-07-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8855397
• 关键词: Environmental Epidemiology; Postdoctoral Fellow; Research Training; environmental toxicology

 DESCRIPTION (provided by applicant) The objective of the Environmental Toxicology and Epidemiology Program (ETEP) is to train future leaders in environmental health sciences (EHS) who accelerate improvements in public health. This program is based on the premise that transformative research in EHS requires scientists with specialized knowledge who engage in multidisciplinary research. This program focuses on translational applications to human disease prevention with training that bridges environmental mechanistic toxicology (basic research) and molecular epidemiology (population-based research) (i.e., T3 translational research). The investigators' focus emphasizes the application of molecular tools such as biomarkers of toxicant exposure/response, genomics, epigenomics, metabolomics, proteomics, and transcriptomics to conduct mechanistically-oriented research in laboratory models and human populations. The proposed training continues their highly successful program, moving into our 32nd year of NIEHS support. Pre-doctoral trainees specialize in environmental epidemiology or mechanistic toxicology, and take a foundation course and an advanced course in the non-specialization area (i.e., epidemiology trainees take toxicology courses and vice versa). In addition, there is a common core curriculum that consists of a bioinformatics course and a course in professional communication and development. The investigators request 8 pre-doctoral and 3 postdoctoral positions (at levels 0, 1 and 2) in this submission, increased from 6 pre-doctoral fellowships and continuing 3 postdoctoral fellowships from the last cycle. The expected duration of trainee support on this training grant is two years, though the expected total duration of pre-doctoral training is 4-5 years. Pre-doctoral and postdoctoral trainees will be encouraged to submit Individual NRSA Fellowship applications (F31 or F32, respectively). Alternatively, postdoctoral trainees may be encouraged to submit K99/R00 application. Qualified applicants must demonstrate motivation for careers in EHS mechanistic toxicology or mechanistically-oriented epidemiology research. Pre-doctoral trainees must have a baccalaureate degree with relevant scientific coursework preparation and will be enrolled in a Ph.D. program in the Department of Environmental Health Sciences, which has a distinguished history of graduate training in toxicology. Postdoctoral fellows must have the Ph.D., M.D., DVM, or other appropriate doctoral degree. The program addresses most of the themes and strategic goals of the NIHES 2012-2017 Strategic Plan, and aims to advance the mission of the NIEHS "to discover how the environment affects people in order to promote healthier lives."

 描述(由申请人提供) 环境毒理学和流行病学计划(ETEP)的目标是培养未来的环境健康科学(EHS)领导者，他们将加快公共健康的改善。该计划的前提是，在EHS中进行变革性研究需要具有专门知识的科学家从事多学科研究。该计划侧重于人类疾病预防的转化应用，培训将环境机械性毒理学(基础研究)和分子流行病学(基于人群的研究)(即，T3转化研究)联系起来。研究人员的重点是应用分子工具，如毒物暴露/反应的生物标记物、基因组学、表观基因组学、代谢组学、蛋白质组学和转录组学，在实验室模型和人类群体中进行以机械为导向的研究。拟议的培训继续他们非常成功的计划，进入我们的NIEHS支持的第32个年头。博士前实习生专门学习环境流行病学或机械毒理学，并在非专业领域学习基础课程和高级课程(即，流行病学实习生学习毒理学课程，反之亦然)。此外，还有一个共同的核心课程，由生物信息学课程和专业交流与发展课程组成。在本报告中，调查人员要求提供8个博士后和3个博士后职位(级别为0、1和2)，比上一个周期的6个博士后奖学金和3个博士后奖学金有所增加。虽然博士前培训的预计总期限为4-5年，但这笔培训补助金的学员支持期限预计为两年。博士后和博士后实习生将被鼓励提交个人NRSA奖学金申请(分别为F31或F32)。或者，博士后实习生可以被鼓励提交K99/R00申请。合格的申请者必须表现出从事EHS机械性毒理学或机械性流行病学研究的动机。博士前实习生必须拥有相关科学课程准备的学士学位，并将参加环境健康科学系的博士项目，该系在毒理学研究生培训方面有着杰出的历史。博士后研究员必须拥有博士、医学博士、DVM或其他适当的博士学位。该计划涉及NIHES 2012-2017战略计划的大部分主题和战略目标，旨在推进NIEHS的使命，即“发现环境如何影响人们，以促进更健康的生活”。