BIOSTATISTICAL AND DATA MANAGEMENT CORE

生物统计和数据管理核心

• 批准号: 8521394
• 负责人: HOWARD F. ANDREWS
• 金额: $ 34.18万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8521394
• 关键词: Accounting; Acute; Appointment; Biometry; Blood Vessels; Blood specimen; Case Report Form; Cause of Death; Characteristics; Clinical Data; Clinical Trials; Collaborations; Collection; Communication; Confidentiality; Consultations; Data; Data Analyses; Data Base Management; Data Collection; Data Coordinating Center; Data Security; Data Storage and Retrieval; Databases; Documentation; Electronics; Ensure; Event; Funding; Generations; Goals; Head; Health Insurance Portability and Accountability Act; Home visitation; House Call; Image; Individual; Institutes; Investigation; Laboratories; Leadership; Maintenance; Manuscripts; Maps; Medical; Modeling; Modification; Monitor; National Institute of Neurological Disorders and Stroke; Neurologic; Neurology; New York; Observational Study; Online Systems; Outcome; Output; Participant; Phase; Postdoctoral Fellow; Preparation; Principal Investigator; Procedures; Program Reviews; Protocols documentation; Public Health Schools; Publications; Recovery; Regulation; Reporting; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Retrieval; Safety; Schedule; Scientist; Secure; Security; Site; Statistical Methods; Stroke; System; Technology; Testing; Universities; Update; Visit; Vital Status; Work; acute stroke; base; computerized; data management; data sharing; database design; design; experience; follow-up; high standard; instrument; medical examination; meetings; mortality; nervous system disorder; neuroimaging; neuroprotection; patient safety; prevent; programs; quality assurance; research and development; statistics

Data for all SPOTRIAS projects has been managed for the previous five years, and will continue to be managed in the renewal period within a single integrated Columbia SPOTRIAS database designed and maintained under the oversight of BDM core leader Dr. Howard Andrews. Dr. Andrews is also director of the Data Coordinating Center (DCC) at the Columbia Mailman School of Public Health (MSPH), which is affiliated with the MSPH Biostatistics Department and which also serves the New York State Psychiatric Institute (NYSPl), a Columbia affiliate. The SPOTRIAS database resides on a physically and electronically secure server cluster maintained by the IT staff of NYSPl. Mr. Greg Neils, the Core B database manager, in consultation with Dr. Andrews and SPOTRIAS investigators and coordinators, and with the assistance of the Core B programmer, Mr. David Merie, designed and implemented the Columbia SPOTRIAS integrated SPOTRIAS database and the key functionalities that have been incorporated into the database over the past five years. Senior statisticians with primary appointments in the MSPH Biostatistics Department, Dr. Myunghee Paik and Dr. Ken Cheung, have traditionally overseen statistical consultation and data analysis for Clinical Trials in the Department of Neurology, have provided leadership for the SPOTRIAS statistical component for the past five years, and will continue to do so in the proposed renewal period. Dr. Eric Zarahn, Associate Research Scientist at the Neurological Institute, is an expert in neuroimaging data analysis, including Statistical Parametric Mapping and Dynamic Causal Modeling. Dr. Paik will provide overall leadership of the Statistics Component, statistical design consultation to DESERVE (Project 3, Discharge Educational Strategies in Stroke to Encourage Reduction of Vascular Events), and will oversee the work of the data analyst, Margaret Doyle, who conducts the analyses for Projects 1 and 2. Dr. Cheung is the senior statistician for NeuSTART (Project 1, Neuroprotection with Statin Therapy for Acute Recovery Trial), and Dr. Zarahn is senior statistician for Project 2, Recovery after Acute Stroke: a Multi-modal Investigation.

所有 SPOTRIAS 项目的数据已在过去五年中得到管理，并将继续 在更新期间，在 BDM 核心领导人 Howard Andrews 博士的监督下设计和维护的单一集成 Columbia SPOTRIAS 数据库中进行管理。 Andrews 博士还是哥伦比亚梅尔曼公共卫生学院 (MSPH) 数据协调中心 (DCC) 的主任，该中心隶属于 MSPH 生物统计学系，并为哥伦比亚大学附属机构纽约州精神病研究所 (NYSPl) 提供服务。 SPOTRIAS 数据库驻留在由 NYSPl 的 IT 人员维护的物理和电子安全服务器集群上。 Core B 数据库经理 Greg Neils 先生与 Andrews 博士和 SPOTRIAS 研究人员和协调员协商，并在 Core B 程序员 David Merie 先生的协助下，设计并实施了哥伦比亚 SPOTRIAS 集成 SPOTRIAS 数据库以及过去五年中已纳入该数据库的关键功能。在 MSPH 生物统计部门担任主要职务的高级统计学家 Myunghee Paik 博士和 Ken Cheung 博士传统上负责监督神经病学部门临床试验的统计咨询和数据分析，在过去五年中为 SPOTRIAS 统计部分提供领导，并将在拟议的更新期内继续这样做。埃里克·扎拉恩博士， 神经学研究所副研究员，是神经影像数据分析专家，包括统计参数映射和动态因果建模。白博士将全面领导统计部分、DESERVE 的统计设计咨询（项目 3，放电中风教育策略以鼓励减少血管事件），并将监督数据分析师 Margaret Doyle 的工作，后者负责项目 1 和 2 的分析。 Cheung 博士是 NeuSTART 的高级统计学家（项目 1，他汀类药物治疗急性恢复的神经保护）试验）和 Zarahn 博士 是项目 2“急性中风后恢复：多模式调查”的高级统计学家。