基因、环境-猫眼课题宝

基因、环境

批准号：

8821809

负责人：

DANIELLE M DICK

金额：

$13.03万

依托单位：

VIRGINIA COMMONWEALTH UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

2010

资助国家：

美国

项目状态：

已结题

起止时间：

2010-02-01 至 2020-08-31

来源：

https://reporter.nih.gov/project-details/8821809

关键词：

Address Adolescence Adolescent and Young Adult Age Alcohol abuse Alcohol consumption Alcohol dependence Alcohol or Other Drugs use Alcohols Area Birth Candidate Disease Gene Child Childhood Collection Communities DNA Data Data Collection Development Development Plans Early Intervention Effectiveness Enrollment Environment Epidemiology Family Funding Gene Family Genes Genetic Genetic Predisposition to Disease Genetic Risk Genotype Goals Grant Health Independent Scientist Award Individual Intervention Intervention Studies K-Series Research Career Programs Knowledge Lead Literature Outcome Paper Pathway interactions Peer Review Phenotype Population Prevention Prevention Research Prevention program Preventive Intervention Publishing Randomized Registries Research Research Support Risk Role Sampling Science Site Staging Students Surveys Testing Time Twin Multiple Birth Twin Studies Universities alcohol misuse alcohol related problem alcohol use disorder base career career development checkup examination cohort college early adolescence early childhood follow-up gene environment interaction genetic information high risk interest intervention program kindergarten neglect population based programs prospective research and development tool university student young adult

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中文摘要

翻译

描述（由申请人提供）：本申请是我的K 02奖的延续，该奖项的既定目标是开发一个跨学科的研究项目，旨在通过整合双胞胎研究，基因鉴定项目和纵向，基于社区的样本的结果，促进我们对遗传影响如何影响酒精使用障碍发展的理解。在项目的过去四年中，我的K奖提供了受保护的研究时间，我发表了70多篇同行评审论文，并获得了三个新的R 01，同时继续担任PI/现场PI的角色。在更新我的K 02时，我建议扩大我的研究计划，将预防/干预研究纳入其中，以实现

英文摘要

DESCRIPTION (provided by applicant): This application is a renewal of my K02 award, which had the stated goal of developing an interdisciplinary program of research aimed at advancing our understanding of how genetic influences impact the development of alcohol use disorders by integrating findings across twin studies, gene identification projects, and longitudinal, community-based samples. Over the past four years of the project, with the protected research time afforded by my K award, I have published >70 peer-reviewed papers and obtained three new R01s, while continuing my role as PI/site PI on four additional existing grants. In the renewal of my K02, I propose to expand my program of research to incorporate prevention/intervention studies in order to actualize on the

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