Test of an Adolescent Anxiety Sensitivity Amelioration Program for At-Risk Youth

针对高危青少年的青少年焦虑敏感性改善计划的测试

• 批准号: 8900131
• 负责人: Ashley Arehart Knapp
• 金额: $ 3.25万
• 依托单位: UNIVERSITY OF ARKANSAS AT FAYETTEVILLE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8900131
• 关键词: Address; Adolescence; Adolescent; Adult; Anxiety; Anxiety Disorders; Appointment; Attenuated; Characteristics; Cognitive; Cognitive Therapy; Complement; Data; Development; Diagnostic; Disease; Distal; Effectiveness; Esthesia; Evaluation; Exercise; Family; Fright; Funding; Generalized Anxiety Disorder; Goals; Health; Human; Hyperventilation; Individual; Institute of Medicine (U.S.); Interpersonal Relations; Intervention; Investigation; Laboratories; Learning; Literature; Long-Term Effects; Mission; Modeling; Modification; Nature; Onset of illness; Outcome; Panic; Panic Attack; Parents; Participant; Pathology; Patient Self-Report; Performance; Phase; Play; Positioning Attribute; Prevention; Prevention program; Primary Health Care; Principal Investigator; Procedures; Process; Protocols documentation; Psychopathology; Public Health; Randomized; Recommendation; Relative (related person); Research; Research Project Grants; Research Support; Resources; Risk; Risk Factors; Role; Safety; Sampling; Schools; Scientist; Specific qualifier value; Symptoms; Syndrome; Testing; Training; Training Programs; United States National Institutes of Health; Work; Youth; anxiety sensitivity; anxious; base; brief intervention; cost; design; economic cost; evidence base; functional disability; generalized anxiety; high risk; indexing; intervention program; malleable risk; meetings; neglect; physical conditioning; post intervention; prevent; programs; prospective; psychoeducation; psychosocial; public health relevance; skills

DESCRIPTION (provided by applicant): Principal Investigator's (PI) goal is to be a scientist in a research-oriented academic setting with a research program focused on preventing anxiety psychopathology among adolescents. A comprehensive training plan was therefore constructed to systematically advance the PI's: 1) expertise regarding conceptual models of broad-based risk factors pertinent to anxiety psychopathology; 2) methodological proficiency related to the sophisticated assessment of anxiety-related vulnerability and pathology; and 3) understanding of the development, evaluation, implementation, analysis, and dissemination of prevention programs targeting youth. Importantly, the proposed study is designed to complement the training program by helping the PI to refine relevant research skills while completing an initial test of an adolescent risk factor reduction program. The proposed sample will consist of 88 adolescents (10 to 14 years) with elevated levels of anxiety sensitivity (AS), a cognitive vulnerability variable reflecting fear of the consequences of anxiety. Adult research supports the effectiveness of targeting AS in terms of preventing panic specifically, and anxiety psychopathology generally. AS is thus a "broad-based" risk factor with the potential to impact multiple disorders. Risk factor research suggests AS modification among youth has implications for panic as well as generalized anxiety disorder. However, very little work has evaluated the impact of AS reduction among youth, which is unfortunate given adolescence is a period of "core risk" in terms of anxiety disorder onset. Further, no work has considered the effect of such a program on GAD-relevant outcomes, nor has any work included family-level intervention factors, despite evidence suggesting parents likely play a critical role in promoting prevention programming. To address these notable gaps in the literature, the primary aim of this project is to experimentally test the effects of an Adolescent Anxiety Sensitivity Amelioration Program (AASAP). High AS youth and a parent will be randomly assigned to either the AASAP, which consists of a single 50min session of psychoeducation and experimenter-led interoceptive exposure, or a general health information control condition. Immediate, two-week, and four-week effects of the AASAP will be evaluated, including effects on self-reported AS, panic attack symptoms, and symptoms of generalized anxiety. Further, the program is expected to impact panic- and GAD-relevant vulnerability indexed using sophisticated challenge procedures. This project aligns with the public health mission of the National Institutes of Health, along with multiple recent calls to train sophisticated prevention scientists. Specifically, given the considerable human suffering and economic costs associated with anxiety psychopathology, it is critically important to construct tailored intervention programs for adolescents at risk for developing such problems. We expect that as a result of this project we will have developed a well-specified psychosocial intervention program for adolescents that targets empirically supported processes with relevance to multiple anxiety-relevant conditions.

描述（由申请人提供）：主要研究者（PI）的目标是成为一名科学家，在一个以研究为导向的学术环境中，研究项目的重点是预防青少年的焦虑精神病理学。因此，构建了一个全面的培训计划，以系统地提高PI的：1）有关焦虑心理病理学的广泛风险因素的概念模型的专业知识; 2）与焦虑相关的脆弱性和病理学的复杂评估相关的方法熟练度; 3）对针对青年的预防计划的开发，评估，实施，分析和传播的理解。重要的是，拟议的研究旨在通过帮助PI完善相关研究技能来补充培训计划，同时完成青少年风险因素降低计划的初步测试。拟议的样本将包括88名青少年（10至14岁）与焦虑敏感性（AS），认知脆弱性变量反映了焦虑的后果的恐惧水平升高。成人研究支持针对AS的有效性，特别是在预防恐慌方面，以及一般的焦虑心理病理学。因此，AS是一个“广泛的”风险因素，有可能影响多种疾病。风险因素研究表明，AS在年轻人中的修正与恐慌和广泛性焦虑症有关。然而，很少有工作评估的影响，减少青年，这是不幸的青春期是一个“核心风险”的时期，在焦虑症发作。此外，没有工作考虑到这样一个方案对GAD相关结果的影响，也没有任何工作包括家庭层面的干预因素，尽管有证据表明父母可能在促进预防规划中发挥关键作用。为了解决这些显着的差距，在文献中，本项目的主要目的是实验测试青少年焦虑敏感性改善计划（AASAP）的影响。高AS青年和父母将被随机分配到AASAP，其中包括一个单一的50分钟的心理教育和实验者主导的内感受性暴露，或一般健康信息控制条件。将评估AASAP的即刻、两周和四周效应，包括对自我报告的AS、惊恐发作症状和广泛性焦虑症状的影响。此外，该计划预计将影响恐慌和GAD相关的脆弱性索引使用复杂的挑战程序。该项目与美国国立卫生研究院的公共卫生使命保持一致，沿着最近多次呼吁培养复杂的预防科学家。具体而言，考虑到相当大的人类痛苦和经济成本与焦虑的精神病理学，这是至关重要的是，构建量身定制的干预方案，为青少年在发展中国家的风险，这些问题。我们期望，作为这个项目的结果，我们将制定一个明确的青少年心理社会干预计划，目标是经验支持的过程与多种焦虑相关的条件。