Test of an Adolescent Anxiety Sensitivity Amelioration Program for At-Risk Youth

针对高危青少年的青少年焦虑敏感性改善计划的测试

• 批准号: 8900131
• 负责人: Ashley Arehart Knapp
• 金额: $ 3.25万
• 依托单位: UNIVERSITY OF ARKANSAS AT FAYETTEVILLE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8900131
• 关键词: Address; Adolescence; Adolescent; Adult; Anxiety; Anxiety Disorders; Appointment; Attenuated; Characteristics; Cognitive; Cognitive Therapy; Complement; Data; Development; Diagnostic; Disease; Distal; Effectiveness; Esthesia; Evaluation; Exercise; Family; Fright; Funding; Generalized Anxiety Disorder; Goals; Health; Human; Hyperventilation; Individual; Institute of Medicine (U.S.); Interpersonal Relations; Intervention; Investigation; Laboratories; Learning; Literature; Long-Term Effects; Mission; Modeling; Modification; Nature; Onset of illness; Outcome; Panic; Panic Attack; Parents; Participant; Pathology; Patient Self-Report; Performance; Phase; Play; Positioning Attribute; Prevention; Prevention program; Primary Health Care; Principal Investigator; Procedures; Process; Protocols documentation; Psychopathology; Public Health; Randomized; Recommendation; Relative (related person); Research; Research Project Grants; Research Support; Resources; Risk; Risk Factors; Role; Safety; Sampling; Schools; Scientist; Specific qualifier value; Symptoms; Syndrome; Testing; Training; Training Programs; United States National Institutes of Health; Work; Youth; anxiety sensitivity; anxious; base; brief intervention; cost; design; economic cost; evidence base; functional disability; generalized anxiety; high risk; indexing; intervention program; malleable risk; meetings; neglect; physical conditioning; post intervention; prevent; programs; prospective; psychoeducation; psychosocial; public health relevance; skills

DESCRIPTION (provided by applicant): Principal Investigator's (PI) goal is to be a scientist in a research-oriented academic setting with a research program focused on preventing anxiety psychopathology among adolescents. A comprehensive training plan was therefore constructed to systematically advance the PI's: 1) expertise regarding conceptual models of broad-based risk factors pertinent to anxiety psychopathology; 2) methodological proficiency related to the sophisticated assessment of anxiety-related vulnerability and pathology; and 3) understanding of the development, evaluation, implementation, analysis, and dissemination of prevention programs targeting youth. Importantly, the proposed study is designed to complement the training program by helping the PI to refine relevant research skills while completing an initial test of an adolescent risk factor reduction program. The proposed sample will consist of 88 adolescents (10 to 14 years) with elevated levels of anxiety sensitivity (AS), a cognitive vulnerability variable reflecting fear of the consequences of anxiety. Adult research supports the effectiveness of targeting AS in terms of preventing panic specifically, and anxiety psychopathology generally. AS is thus a "broad-based" risk factor with the potential to impact multiple disorders. Risk factor research suggests AS modification among youth has implications for panic as well as generalized anxiety disorder. However, very little work has evaluated the impact of AS reduction among youth, which is unfortunate given adolescence is a period of "core risk" in terms of anxiety disorder onset. Further, no work has considered the effect of such a program on GAD-relevant outcomes, nor has any work included family-level intervention factors, despite evidence suggesting parents likely play a critical role in promoting prevention programming. To address these notable gaps in the literature, the primary aim of this project is to experimentally test the effects of an Adolescent Anxiety Sensitivity Amelioration Program (AASAP). High AS youth and a parent will be randomly assigned to either the AASAP, which consists of a single 50min session of psychoeducation and experimenter-led interoceptive exposure, or a general health information control condition. Immediate, two-week, and four-week effects of the AASAP will be evaluated, including effects on self-reported AS, panic attack symptoms, and symptoms of generalized anxiety. Further, the program is expected to impact panic- and GAD-relevant vulnerability indexed using sophisticated challenge procedures. This project aligns with the public health mission of the National Institutes of Health, along with multiple recent calls to train sophisticated prevention scientists. Specifically, given the considerable human suffering and economic costs associated with anxiety psychopathology, it is critically important to construct tailored intervention programs for adolescents at risk for developing such problems. We expect that as a result of this project we will have developed a well-specified psychosocial intervention program for adolescents that targets empirically supported processes with relevance to multiple anxiety-relevant conditions.

描述（由申请人提供）：首席研究者（PI）的目标是成为以研究为导向的学术环境的科学家，研究计划的重点是预防青少年的焦虑心理病理学。因此，制定了一项全面的培训计划，以系统地推进PI：1）有关与焦虑心理病理学有关的基于广泛风险因素的概念模型的专业知识； 2）与焦虑相关脆弱性和病理的复杂评估有关的方法学能力； 3）了解针对青年的预防计划的发展，评估，实施，分析和传播。重要的是，拟议的研究旨在通过帮助PI提高相关研究技能，同时完成对青少年风险因素减少计划的初步测试，以补充培训计划。提出的样本将由88名青少年（10至14年）组成，其焦虑敏感性升高（AS），这是一种认知脆弱性变量，反映了对焦虑后果的恐惧。成人研究支持针对靶向的有效性，就像预防恐慌以及焦虑心理病理学有关。因此，这是一个“基于广泛的”风险因素，可能会影响多种疾病。危险因素研究表明，年轻人之间的修改对恐慌和普遍的焦虑症具有影响。但是，很少的工作评估了年轻人减少的影响，这是不幸的，因为青春期是焦虑症发作的“核心风险”时期。此外，没有任何工作考虑这种计划对与GAD相关的结果的影响，尽管有证据表明父母可能在促进预防计划中起着至关重要的作用，但也没有任何工作包括家庭水平的干预因素。为了解决文献中这些显着的差距，该项目的主要目的是实验测试青少年焦虑敏感性改善计划（AASAP）的影响。高年轻人和父母将被随机分配到AASAP，该AASAP由一次50分钟的心理教育和实验者主导的感知性暴露或一般健康信息控制条件组成。将评估AASAP的直接，两周和为期四周的影响，包括对自我报告的恐慌攻击症状的影响以及广义焦虑的症状。此外，该计划有望影响使用复杂的挑战程序索引的恐慌和与GAD相关的脆弱性。该项目与美国国立卫生研究院的公共卫生任务保持一致，以及最近培训先进的预防科学家的多次呼吁。具体而言，鉴于与焦虑心理病理学相关的大量人类苦难和经济成本，为面临危险的青少年构建量身定制的干预计划至关重要。我们预计，由于这个项目，我们将针对青少年制定一个明确指定的社会心理干预计划，该计划针对凭经验支持的过程，与多种焦虑症相关。