Virology Training Grant

描述(由申请者提供)：经过一个富有成效的第一个资助期后，我们提交了NIAID资助的T32“病毒学培训补助金”的竞争性续签申请。从病毒学研究中获得的知识导致了对基本细胞过程的许多基本见解，如复制、转录、翻译、肿瘤发生机制和宿主免疫。病毒是导致人类痛苦和死亡的重要病原体。在威斯康星大学，病毒学是一个主要的研究重点，有20多个资金充足的病毒学教员研究各种各样的病毒，从感染植物和昆虫的病毒到导致人类癌症的病毒。其他活跃的研究领域包括对新出现的病毒，如埃博拉病毒和新的高致病性流感病毒株的研究。20多年前，罗兰·鲁克特博士和霍华德·特明博士创建了麦迪逊病毒学课程，开始了在麦迪逊开发综合病毒学培训课程的努力。该T32是我们的培训计划的基石，博士后和博士后学员感兴趣的方方面面的病毒学在这个校园。我们培训计划的亮点包括广泛的病毒学课程，所有培训师和受训人员参加的每周一次的分子病毒学研讨会系列，以及与之相关的特定指导活动，职业发展的多方面方法，强调获得撰写助学金和手稿以及口头演示的技能，伦理学培训，以及一年一度的全计划病毒学静修。博士后和博士后学员参加所有培训活动，每年举办研讨会，接受伦理学培训，如果是博士后，则辅修病毒学。除了校园范围内的系列研讨会和务虚会外，校园内的病毒学实验室之间还有许多合作项目，以及实验室间的小组会议，以促进思想交流。通过年度研讨会、培训补助金指导委员会的年度评价以及与个别导师的互动以及联合主任和行政助理的方案监督，在多个层面监测每个受训人员的进展情况。我们吸引优秀博士后学员的能力体现在我们的校园在微生物学领域排名全国第三。我们招募优秀的博士后和博士后实习生到我们的实验室，通过结合每个培训者的研究计划的个人力量，在病毒学方面的机会，我们的组织和 在麦迪逊举办病毒学会议，将来自美国各地的学生带到麦迪逊，他们亲身体验我们的学术社区，以及我们非常成功的少数族裔招聘工作。我们在培养病毒学家方面取得了良好的成绩，我们实验室三分之一的PAS实习生目前担任教职，90%的人在生物医学科学领域工作，这有力地证明了我们有能力培养下一代杰出的病毒学家。

DESCRIPTION (provided by applicant): After a productive first funding period, we submit this competitive renewal application for the NIAID-funded T32, "Virology Training Grant". Knowledge gained from research in virology has led to many fundamental insights about basic cellular processes such as replication, transcription, translation, mechanisms of oncogenesis, and host immunity. Viruses are important pathogens that contribute greatly to human misery and death. At the University of Wisconsin, virology is a major focus of study, with over 20 well-funded virology faculty studying a wide variety of viruses, from those that infect plants and insects, to those that cause human cancer. Additional vibrant areas of research include studies on emerging viruses such as Ebola and new strains of highly pathogenic influenza virus. An effort to develop an integrated virology training program in Madison began over 20 years ago with the creation of the Madison Virology Program by Drs. Roland Rueckert and Howard Temin. This T32 is the cornerstone of our training program for predoc and postdoc trainees interested in all aspects of virology on this campus. Highlights of our training program's training activities includes an extensive virology curriculum, a campus wide weekly Molecular Virology Seminar series attended by all trainers and trainees with specific mentoring activities associated with it,a multifaceted approach to career development that emphasizes acquisition of skills in writing grants and manuscripts as well as in oral presentations, training in ethics, and an annual, program-wide virology retreat. Predoc and postdoc trainees participate in all training activities, present yearly seminars, are trained in ethics, and, in the case of predocs, obtain a minor focused on virology. In addition to the campus wide seminar series and retreat, there are many collaborative projects between virology labs on campus as well as interlab group meetings that foster the exchange of ideas. Progress of each trainee is monitored at multiple levels through yearly seminars, yearly evaluations by the training grant's Steering Committee, as well as interactions with the individual mentor and programmatic oversight by the co-Directors and the administrative assistant. Our ability to attract outstanding predoc trainees is reflected in our campus being ranked 3rd in the nation in the field of Microbiology. We recruit outstanding predoc and postdoc trainees to our labs through a combination of the individual strength of each of the trainer's research program, the breadth of the opportunities in virology, our organizing and hosting virology meetings in Madison that bring to Madison students from across the US who get to experience first hand our academic community, and our highly successful minority recruiting efforts. Our strong record of achievement in training virologists, with one third of pas trainees from our labs now holding faculty positions and >90% working in the biomedical sciences, provides strong evidence for our capability to train the next generation of outstanding virologists.