Centralized Research Instrumentation Core (CRI)

集中式研究仪器核心 (CRI)

• 批准号: 9901300
• 负责人: CARMEN LYDIA CADILLA
• 金额: $ 29.65万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9901300
• 关键词: Animal Model; Area; Bacteria; Biological Models; Biological Testing; Biomedical Research; Centers of Research Excellence; Collaborations; Communities; Comprehensive Cancer Center; Consult; Consultations; Core Facility; Data; Data Analyses; Development; Doctor of Philosophy; Educational workshop; Ensure; Experimental Designs; Faculty; Funding; Generations; Genetic; Genomics; Goals; Human; Human Genetics; Infrastructure; Institutes; Institution; Interdisciplinary Study; International; Lead; Medical; Mentors; Mentorship; Piedra; Postdoctoral Fellow; Proteomics; Puerto Rico; Research; Research Personnel; Research Project Grants; Resources; Science; Secure; Services; Students; Technology; United States National Institutes of Health; Universities; Work; experience; health disparity; human genomics; innovative technologies; instrumentation; meetings; metabolomics; minority health; outreach; programs; research facility; tissue/cell culture; training opportunity; undergraduate student

Project Summary The overall goal of the PR-INBRE Centralized Research Instrumentation (CRI) Cores is to integrate and empower Faculty investigators, students and postdocs from the Lead, Primarily Undergraduate Institutions (PUIs), and Outreach Institutions by providing mentorship and scientific support. The PR-INBRE CRI will incorporate core facilities supported by PR-INBRE and other collaborating facilities supported by National Institutes of Health (NIH) infrastructure programs such as the National Institute on Minority Health and Health Disparities (NIMHD)-funded University of Puerto Rico Medical Sciences Campus (UPR-MSC) RCMI program, and with UPR institutional funds. Several of these core facilities have been operating for 14 or more years with M.S. and Ph.D.-level experienced technicians and committed scientific staff. The following facilities will participate in the proposed CRI in the next cycle: the RCMI/PR-INBRE Human Genetics and Genomics Core Lab at UPR-MSC; the PR-INBRE Metabolomics Core at UPR- MSC; the PR-INBRE Sequencing and Genomics Facility at UPR-Rio Piedras; the PR-INBRE ChEMTox Biotesting Core at Universidad Ana G. Mendez Cupey Campus and the PR- INBRE/RCMI Translational Proteomics Core at the UPR-Comprehensive Cancer Center. Their efforts support local, national and international collaborations. To fulfill the overall goal of this Core the following specific aims are proposed: 1) Continue to provide access to state-of-the-art core research instrumentation for nurturing new research projects and expanding established research collaborations between the CRI investigators, students, and postdocs from Puerto Rico and other IDeA states. 2) Ensure the effective dissemination of technologies offered by the CRI Cores via theoretical and practical workshops, mentoring researchers in experimental design, data analysis and best practices in the use of the resources available at the CRI Cores. 3) Collaborate with other INBRE and COBRE Core labs to expand access for PR-INBRE investigators to innovative technologies available at other IDeA cores and provide opportunities for professional development of technical and scientific staff by supporting attendance to professional meetings such as the Association of Biomedical Research Facilities (ABRF) and other training opportunities. To assist in the development of an interdisciplinary research effort at the PR-INBRE network institutions, the CRI will provide specialized services such as: direct technical consultation on experimental design, data generation, and analysis in genetics and genomics in human and small animal model systems, proteomics, metabolomics, and biological testing of experimental compounds in bacteria and tissue culture cells.

项目摘要 PR INBRE集中研究仪器（CRI）核心的总体目标是 主要是将领导者的教师调查员，学生和博士后授权，主要是 本科机构（PUI）和外展机构通过提供指导和 科学支持。公关INBRE CRI将结合PR-INBRE支持的核心设施， 国立卫生研究院（NIH）基础设施支持的其他合作设施 诸如国家少数民族健康与健康差异研究所（NIMHD）之类的计划 波多黎各大学医学科学校园（UPR-MSC）RCMI计划，并与UPR 机构资金。这些核心设施中的一些已经运营了14年或更长时间 多发性硬化症。以及博士学位级别的经验丰富的技术人员和科学人员。下列 设施将在下一个周期中参与拟议的CRI：RCMI/PR-INBRE人 UPR-MSC的遗传学和基因组核心实验室； UPR- MSC; UPR-RIO PIEDRAS的PR-INBRE测序和基因组学设施；公关率 Ana G. Mendez Capey校园和Pr-的Chemtox Biotesting Core UPR全面癌症中心的Inbre/RCMI转化蛋白质组学核心。他们的 努力支持本地，国家和国际合作。实现这一总体目标 核心提出了以下特定目标：1）继续提供最先进的访问权限 核心研究工具，用于培育新的研究项目并扩大已建立 波多黎各的CRI调查人员，学生和博士后的研究合作 和其他想法状态。 2）确保CRI提供的技术有效传播 通过理论和实用研讨会的核心，指导研究人员实验设计， 数据分析和最佳实践在使用CRI内核的资源方面。 3） 与其他近亲和Cobre Core Labs合作，以扩展PR Inbre的访问 调查人员到其他想法核心可用的创新技术，并提供机会 通过支持参加的技术和科学人员的专业发展 专业会议，例如生物医学研究设施协会（ABRF）和 其他培训机会。协助开发跨学科研究工作 在公关网络机构，CRI将提供专业服务，例如：直接 关于遗传学的实验设计，数据生成和分析的技术咨询和 人和小动物模型系统，蛋白质组学，代谢组学和生物学的基因组学 测试细菌和组织培养细胞中实验化合物。