Multicompartment quantification of tissue in vitro and in vivo with magnetic resonance imaging and spectroscopy
Multicompartment quantification of tissue in vitro and in vivo with magnetic resonance imaging and spectroscopy
批准号:
9147376
负责人:
Richard Spencer
金额:
$6.41万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
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英文摘要
We are developing relaxometry and related methods to probe macromolecular compartments withing cartilage, brain, and muscle. The goal is to identify mobility, concentration, and exchange between hydration compartments within tissue. It is well-known that changes in these features play a prominent role in pathology associated with both aging and disease. We are using compressed sensing as a modality to move to a more translational aspect to these studies. Overall, this work should expand the capability of chemical-physical probes of disease, permitting evaluation of progression and of therapies using noninvasive magnetic resonance technology.
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会议论文
Accurate Quantification in Physiologic Phosphorus MR Spectroscopy
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批准号:8736647
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项目类别:
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资助金额:$9.52万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Magnetic Resonance Analysis of Connective Tissue and Muscle
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批准号:8335965
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项目类别:
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资助金额:$7.83万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Multicompartment quantification of tissue in vitro and in vivo with magnetic resonance imaging and spectroscopy
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批准号:10252565
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项目类别:
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资助金额:$1.63万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Advanced magnetic resonance imaging of the human brain in normative aging, cognitive impairment, and dementia
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批准号:10688802
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项目类别:
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资助金额:$2.79万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Accurate Quantification in Physiologic Phosphorus MR Spectroscopy
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批准号:10688868
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项目类别:
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资助金额:$26.58万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Magnetic Resonance Analysis of Connective Tissue and Muscle
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批准号:7732353
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项目类别:
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资助金额:$4.35万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Accurate Quantification in Physiologic Phosphorus MR Spectroscopy
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批准号:7964093
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项目类别:
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资助金额:$14.26万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Improving Sensitivity and Specificity of Parametric MRI Assessment of Cartilage
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批准号:7964089
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项目类别:
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资助金额:$40.41万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Anabolic Interventions in Engineered Cartilage and Degenerative Joint Disease
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批准号:7964090
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项目类别:
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资助金额:$29.71万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Advanced magnetic resonance imaging of the human brain in normative aging, cognitive impairment, and dementia
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批准号:10913064
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项目类别:
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资助金额:$11.18万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Magnetic Resonance Analysis of Connective Tissue and Muscle
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批准号:7964091
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项目类别:
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资助金额:$5.7万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Magnetic Resonance Imaging and Spectroscopy of Rodent Models of Disease
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批准号:10688869
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项目类别:
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资助金额:$46.51万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Multicompartment quantification of tissue in vitro and in vivo with magnetic resonance imaging and spectroscopy
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批准号:10688872
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项目类别:
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资助金额:$112.95万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Magnetic Resonance Imaging and Spectroscopy of Rodent Models of Disease
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批准号:7732356
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项目类别:
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资助金额:$18.14万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Accurate Quantification in Physiologic Phosphorus MR Spectroscopy
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批准号:10913156
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项目类别:
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资助金额:$23.21万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Magnetic Resonance Analysis of Connective Tissue and Muscle
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批准号:10008626
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项目类别:
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资助金额:$65.88万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Advanced magnetic resonance imaging of the human brain in normative aging, cognitive impairment, and dementia
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批准号:10252544
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项目类别:
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资助金额:$3.26万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Anabolic Interventions in Engineered Cartilage and Degenerative Joint Disease
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批准号:8148343
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项目类别:
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资助金额:$37.77万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
NMR STUDIES OF PHYSIOLOGY AND BIOCHEMISTRY IN CELLS, ORGANS AND ANIMALS
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批准号:6097823
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
Magnetic Resonance Imaging and Spectroscopy of Rodent Models of Disease
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批准号:8552510
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项目类别:
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资助金额:$40.69万
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财政年份:--
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负责人:Richard Spencer
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依托单位:
国内基金
海外基金
Sitagliptin通过microbiota-gut-brain轴在2型糖尿病致阿尔茨海默样变中的脑保护作用机制
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批准号:81801389
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项目类别:青年科学基金项目
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资助金额:21.0万元
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批准年份:2018
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负责人:田茗源
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依托单位:
平扫描数据导引的超低剂量Brain-PCT成像新方法研究
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批准号:81101046
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项目类别:青年科学基金项目
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资助金额:23.0万元
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批准年份:2011
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负责人:黄静
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依托单位: