Inner City Asthma consortium 3 (ICAC3)
Inner City Asthma consortium 3 (ICAC3)
批准号:
8903803
负责人:
William W. Busse
金额:
$1212.54万
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-08-05 至 2021-07-31
关键词:
16 year oldAddressAdolescenceAdolescentAllergen ImmunotherapyAllergensAllergicAnti-CholinergicsAsthmaBacteriaBiologicalBirthCaringCellsCharacteristicsChildChildhoodChildhood AsthmaClinicalCohort StudiesCollaborationsComplexDevelopmentDictyopteraDiseaseDisease ProgressionDisease remissionEnvironmentEnvironmental ExposureEnvironmental Risk FactorEpidemicEpigenetic ProcessEpitopesExposure toGoalsGrantGuidelinesHouse DustHouseholdIgEImmuneImmune responseImmunobiologyImmunologicsImmunotherapyIncidenceInterleukin-5InterventionLeadLeptinLifeLinkMediatingMetabolicMicrobeMulticenter StudiesMuscarinic AntagonistsObesityOutcomeParticipantPeripheral Blood EosinophiliaPhenotypePlasmaPopulationPrevalencePreventionProcessProtocols documentationRecurrenceResearch DesignRespiratory Tract InfectionsRiskRisk FactorsRoleSchool-Age PopulationSeveritiesShapesSourceStimulusSystems BiologyT cell responseT-LymphocyteTestingWheezingWorkairborne allergenallergic airway diseaseasthmaticasthmatic patientbasecockroach allergencohortdesigndisorder controlearly childhoodgastrointestinalgenetic risk factorhigh riskimmunoregulationimprovedin uteroinfancyinner citymepolizumabmicrobialmicrobiomemouse allergenomalizumabpreventrespiratoryresponsesubcutaneoustherapy design
中文摘要
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英文摘要
DESCRIPTION (provided by applicant): ICAC's goal is to include further development of cockroach allergen immunotherapy and consideration of new allergen immunotherapies; for example to mouse allergens; the development and execution of clinical and mechanistic studies targeted to inner-city asthma phenotypes, and interventions designed to prevent the incidence of asthma or its progression. In addition, the URECA birth cohort study will be continued to the end of the grant, when the participants will range from 14 to 16 years of age, with the goal to provide information on the immunologic basis of late childhood and adolescence-onset asthma, as well as the remission of asthma during the same years.
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Inner City Asthma consortium 3 (ICAC3)
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批准号:9110805
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项目类别:
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资助金额:$1032.87万
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财政年份:2014
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负责人:William W. Busse
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依托单位:
Inner City Asthma Consortium
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批准号:8938738
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项目类别:
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资助金额:$200.0万
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财政年份:2009
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负责人:William W. Busse
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依托单位:
INNER CITY ASTHMA CONSORTIUM
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批准号:7952351
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项目类别:
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资助金额:$5628.99万
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财政年份:2009
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负责人:William W. Busse
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依托单位:
CHARACTERIZATION OF SUBJECTS WITH SEVERE ASTHMA
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批准号:7607503
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项目类别:
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资助金额:$0.01万
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财政年份:2006
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负责人:William W. Busse
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依托单位:
FUNCTIONAL ACTIVITY OF AIRWAY EOSINOPHILS IN ALLERGIC DISEASE
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批准号:7607564
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项目类别:
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资助金额:$0.05万
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财政年份:2006
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负责人:William W. Busse
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依托单位:
CYTOKINE/CHEMOKINE RESPONSE IN ASTHMA EXACERBATIONS DUE TO COLDS
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批准号:7375511
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项目类别:
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资助金额:$0.25万
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财政年份:2005
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负责人:William W. Busse
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依托单位:
ROLE AND CONTRIBUTION OF EOSINOPHILS TO THE PATHOGENESIS OF ASTHMA
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批准号:7204336
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项目类别:
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资助金额:$0.34万
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财政年份:2005
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负责人:William W. Busse
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依托单位:
CHARACTERIZATION OF SUBJECTS WITH SEVERE ASTHMA
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批准号:7204361
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项目类别:
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资助金额:$1.24万
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财政年份:2005
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负责人:William W. Busse
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依托单位:
FUNCTIONAL ACTIVITY OF AIRWAY EOSINOPHILS IN ALLERGIC DISEASE
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批准号:7375557
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项目类别:
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资助金额:$0.93万
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财政年份:2005
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负责人:William W. Busse
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依托单位:
CYTOKINE/CHEMOKINE RESPONSE IN ASTHMA EXACERBATIONS DUE TO COLDS
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批准号:7204369
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项目类别:
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资助金额:$0.37万
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财政年份:2005
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负责人:William W. Busse
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依托单位:
FUNCTIONAL ACTIVITY OF AIRWAY EOSINOPHILS IN ALLERGIC DISEASE
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批准号:7204408
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项目类别:
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资助金额:$0.94万
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财政年份:2005
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负责人:William W. Busse
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依托单位:
AIRWAY INFLAMMATION AND REMODELING IN ASTHMA
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批准号:7204407
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项目类别:
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资助金额:$0.15万
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财政年份:2005
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负责人:William W. Busse
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依托单位:
CHARACTERIZATION OF SUBJECTS WITH SEVERE ASTHMA
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批准号:7375505
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项目类别:
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资助金额:$0.59万
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财政年份:2005
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负责人:William W. Busse
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依托单位:
Phase II Evaluation of Allergen Immunotherapy Co-Administered with Omalizumab
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批准号:7043916
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项目类别:
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资助金额:$1.91万
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财政年份:2003
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负责人:William W. Busse
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依托单位:
Role and Contribution of Eosinophils to the Pathogenesis of Asthma
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批准号:7043882
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项目类别:
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资助金额:$1.1万
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财政年份:2003
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负责人:William W. Busse
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依托单位:
Characterization of Subjects with Severe Asthma
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批准号:7043914
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项目类别:
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资助金额:$0.69万
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财政年份:2003
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负责人:William W. Busse
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依托单位:
Airway Inflammation and Remodeling in Asthma
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批准号:7043942
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项目类别:
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资助金额:$0.81万
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财政年份:2003
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负责人:William W. Busse
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依托单位:
Role of the Neutrophil in Subjects with Severe Asthma
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批准号:7043895
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项目类别:
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资助金额:$0.12万
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财政年份:2003
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负责人:William W. Busse
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依托单位:
Role of Cytokine Dysregulation in an in vivo Model of Rhinovirus 16
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批准号:7043873
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项目类别:
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资助金额:$2.72万
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财政年份:2003
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负责人:William W. Busse
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依托单位:
Functional Activity of Airway Eosinophils in Allergic Disease
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批准号:7043944
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项目类别:
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资助金额:$0.69万
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财政年份:2003
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负责人:William W. Busse
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依托单位:
海外基金