Biostatistics (BSR)

项目摘要/摘要：生物统计学共享资源 (BSR) 这一共享资源为所有 Norris Cotton 癌症中心 (NCCC) 项目提供了统计数据的访问权限 专业知识。生物统计共享资源 (BSR) 已成为 30 多个癌症中心的资源 年。生物技术和计算硬件/软件的进步大大增加了对 BSR 提供了复杂的统计方法。生物统计学是重要的科学组成部分 高质量的癌症研究，特别是临床研究的开展。 BSR 拥有 11 名教职人员 统计学家/方法学家和七名统计/数据管理/程序员分析师。托尔·托斯特森， 科学博士，担任教务主任，他已担任该职位 15 年。教师统计专业领域 研究内容包括纵向数据分析和研究设计、临床测量误差方法 研究和流行病学、临床试验和流行病学研究的统计方法、统计方法 用于高维基因组和成像数据、地理空间分析、临床决策建模、成本- 有效性分析和诊断测试评估。 BSR 在 NCCC 的科学发展中发挥着重要作用 （临床癌症研究，CCRC）和数据安全（安全和数据监测，SDMC）委员会 批准和监督临床方案。 BSR主任担任NCCC癌症委员会成员 研究委员会 (CRC) 并每周与其他 NCCC 领导人举行会议。 BSR 教职人员是 NCCC 众多 NCI 资助项目的积极合作者，并定期参加 计划会议。核心贡献了来自 65 名 NCCC 成员的总共 104 个独立项目， 2012-2013 年期间分布在所有 NCCC 项目中。 NCCC 的研究数据管理活动是 与 BSR、NCCC 管理部门、NCCC 临床研究办公室 (OCR) 协调管理， 和生物信息学共享资源（BISR）。 BSR能力显着增强，未来计划 在数据科学系中设立一个新的生物统计司，并提供额外资源 可通过达特茅斯临床和转化科学奖进行研究

Project Summary/Abstract: Biostatistics Shared Resource (BSR) This shared resource provides all Norris Cotton Cancer Center (NCCC) programs with access to statistical expertise. The Biostatistics Shared Resource (BSR) has been a cancer center resource for more than thirty years. Advances in biotechnologies and computing hardware/software have increased greatly the need for the sophisticated statistical methodologies provided by the BSR. Biostatistics is an essential scientific component of high quality cancer research, particularly in the conduct of clinical research. The BSR is staffed by 11 faculty statisticians/methodologists and seven statistical/data management/programmer analysts. Tor Tosteson, Sc.D., serves as the faculty director, a role he has played for 15 years. Areas of faculty statistical expertise and research include longitudinal data analysis and study design, measurement error methods in clinical research and epidemiology, statistical methods for clinical trials and epidemiology studies, statistical methods for high dimensional genomic and imaging data, geospatial analysis, clinical decision modeling, cost- effectiveness analysis, and diagnostic test assessment. The BSR plays a major role in NCCC's scientific (Clinical Cancer Research, CCRC) and data safety (Safety and Data Monitoring, SDMC) committees for approving and monitoring clinical protocols. The Director of the BSR serves as a member of NCCC's Cancer Research Committee (CRC) and meets weekly with the other NCCC leaders. The BSR faculty members are active collaborators on numerous NCI-funded projects throughout NCCC and participate in regularly scheduled Program meetings. The core contributed to a total of 104 separate projects from 65 NCCC members, distributed across all NCCC programs, during 2012-2013. Research data management activities at NCCC are managed in coordination with the BSR, NCCC Administration, the NCCC Office of Clinical Research (OCR), and the Bioinformatics Shared Resource (BISR). BSR capabilities have grown significantly, with future plans to include a new Division of Biostatistics, in a Department of Data Science, and additional resources made available for research through the Dartmouth Clinical and Translational Science Award