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FASEB SRC on Glucose transport:Gateway to Metabolic Systems Biology

FASEB SRC 关于葡萄糖转运：代谢系统生物学的门户

基本信息

批准号：
8977103
负责人：
CHRISTOPHER B NEWGARD
金额：
$ 1.5万
依托单位：
FEDERATION OF AMER SOC FOR EXPER BIOLOGY
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-06-19 至 2016-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8977103
关键词：
Academia American Area Award Biology Cardiovascular Diseases Cell physiology Cells Chronic Disease Cloning Collaborations Communication Data Databases Development Diabetes Mellitus Disabled Persons Disease Ensure Event Faculty Functional disorder Funding Glucose Glucose Transporter Goals Growth Health Hour Industry Institution Lead Life Link Maintenance Malignant Neoplasms Metabolic Metabolic Control Metabolic Diseases Metabolism Methods Minority Montana Muscle Myocardium National Institute of Diabetes and Digestive and Kidney Diseases Nutrient Obesity Participant Pathogenesis Performance Pharmacologic Substance Physiology Protein Isoforms Recording of previous events Regulation Research Research Personnel Running Scheme Scientist Series Signal Transduction Skeletal Muscle Societies Staging Students Systems Biology Technology Testing United States National Institutes of Health Woman abstracting career combat forging glucose transport glucose uptake high standard lectures meetings muscle metabolism new therapeutic target posters public health relevance symposium tool uptake volunteer

项目摘要

DESCRIPTION (provided by applicant): Glucose uptake into cells is a central component of metabolism and energetics. The mechanisms by which glucose-derived energy is used for specific cellular functions such as growth, proliferation and maintenance, and how altered regulation can contribute to development of cardiometabolic diseases and cancer are critically important questions. It is necessary to explore these questions with a broad perspective, in which whole body and cellular mechanisms of cell signaling, nutrient uptake, and metabolism are integrated. Major advances in technology for investigating metabolism-driven chronic diseases have occurred in the past years, including advent of sophisticated platforms for systems biology. These developments facilitate approaches to understanding metabolic complexity that can include hypothesis-driven and database-driven discovery, but also requiring tools to enable hypothesis testing. In the face of these rapid changes, the proposed FASEB summer conference on "Glucose Transport: Gateway to Metabolic Systems Biology" seems particularly timely and important for maximizing communication among groups, forging collaborations, and facilitating progress in the field. Funding from NIDDK will ensure that this series, among the most long-lived in FASEB conference history, will continue to contribute to our understanding of metabolic physiology and its links to disease pathophysiology, while also serving as a vehicle to encourage and nurture young and emerging scientists in the field.