Muscular Dystrophy Cooperative Research Center

肌营养不良症合作研究中心

• 批准号: 9306217
• 负责人: STEVEN A MOORE
• 金额: $ 40.09万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-08 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9306217
• 关键词: Autopsy; Basic Science; Biological Markers; Biopsy; Blood; Cell Culture Techniques; Cells; Clinical; Clinical Trials; Clinics and Hospitals; Consent; Country; Development; Diagnostic; Diagnostic Services; Diagnostic tests; Disease; Evaluation; Fibroblasts; Goals; International; Iowa; Laboratories; Muscle; Muscular Dystrophies; Myoblasts; Myocardial tissue; Neuromuscular Diseases; Online Systems; Operative Surgical Procedures; Pathology; Patients; Procedures; Process; Proteins; Protocols documentation; Research; Research Infrastructure; Research Personnel; Resources; Sampling; Services; Ships; Skeletal Muscle; Techniques; Testing; Therapeutic; Tissues; Translational Research; Universities; Urine; base; dystroglycanopathy; interest; medical specialties; novel diagnostics; repository; research and development; tissue/cell culture

CORE B SUMMARY The Muscle Tissue/Cell Culture/Diagnostics Core of the Iowa Wellstone Muscular Dystrophy Cooperative Research Center is a multifaceted laboratory that serves as a local, national and international resource for research on muscular dystrophy and other neuromuscular diseases. This Core has two major goals. Firstly, it has established and will expand a tissue and cell culture Repository to support basic and translational research efforts. Currently, this Repository contains muscle biopsies from more than 3500 patients with neuromuscular disorders, as well as cryopreserved fibroblasts from more than 300 patients with myopathic disease, predominantly muscular dystrophies. Well-characterized tissues and cells from the Core are made available to research investigators at Iowa as well as other academic centers across the USA and around the world. Secondly, the Core provides specialty diagnostic services that are not readily available through clinical laboratories, and facilitates research on and the development of new diagnostic tests for eventual transfer into clinical laboratories. These diagnostic services are very closely integrated with clinical laboratory testing carried out in the Department of Pathology at the University of Iowa. Together, Core B and the Department of Pathology services provide state-of-the-art diagnostic testing for patients seen at the University of Iowa Hospitals and Clinics, and for patients referred to Iowa from throughout the USA and from several other countries. This infrastructure provides key support for clinical trials of neuromuscular disease.

核心b概述