Promoting Optimal Parenting

促进最佳育儿方式

• 批准号: 9011541
• 负责人: DIMITRI A CHRISTAKIS
• 金额: $ 53.03万
• 依托单位: SEATTLE CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-02-01 至 2018-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9011541
• 关键词: 3 year old; Age; Age-Years; Behavior; Behavior assessment; Birth; Blinded; Brain; Caregivers; Child; Child Development; Child Rearing; Code; Cognitive; Communication; Development; Education; Emotional; Enrollment; Family; Income; Infant; Institute of Medicine (U.S.); Intervention; Language; Life; Low income; Maternal Age; Mediator of activation protein; Mothers; Neighborhoods; Neurons; Parenting Education; Parents; Problem behavior; Procedures; Public Health; Randomized Controlled Trials; Readiness; Recommendation; Research; Research Support; Risk Factors; Schools; Secure; Security; Series; Single Parent; Social support; Testing; Time; Toddler; aged; arm; base; cognitive development; cohort; cost effective; cost effectiveness; critical period; efficacy testing; evidence base; executive function; improved; social skills; tool; young mother

DESCRIPTION (provided by applicant): Considerable existing research supports the notion that the first few years of a child's life are important to their long term cognitive and emotional development. Children's cognitive development during this time frame, especially around language and reciprocal communication, has a profound impact on later ability to succeed in school. Likewise, emotional development during this key developmental period is critical in developing attachment, positive social skills, executive function as well as improving school readiness and reducing behavior problems later on. This proposal aims to test the hypothesis that a series of pragmatic, actionable, evidence-based and cost- effective caregiver behaviors can improve the cognitive and emotional development of children aged 0-3 years. This age is chosen because it represents a critical period of brain development

描述(由申请人提供)：相当多的现有研究支持这样的概念，即儿童生命的头几年对他们长期的认知和情感发展是重要的。儿童在这段时间内的认知发展，特别是围绕语言和相互交流的认知发展，对以后在学校取得成功的能力有着深远的影响。同样，在这个关键的发展阶段，情绪发展对于发展依恋、积极的社交技能、执行功能以及改善上学准备和减少以后的行为问题至关重要。这一建议旨在检验这样一种假设，即一系列务实、可操作、基于证据和成本效益的照顾者行为可以改善0-3岁儿童的认知和情感发展。之所以选择这个年龄，是因为它代表了大脑发育的关键时期

项目成果

Localization of cytochrome P450 cholesterol side-chain cleavage, cytochrome P450 17 alpha-hydroxylase/17, 20-lyase, and 3 beta-hydroxysteroid dehydrogenase isomerase steroidogenic enzymes in human and rhesus monkey fetal adrenal glands: reappraisal of fun

人和恒河猴胎儿肾上腺中细胞色素 P450 胆固醇侧链裂解、细胞色素 P450 17 α-羟化酶/17、20-裂解酶和 3 β-羟基类固醇脱氢酶异构酶类固醇生成酶的定位：乐趣的重新评估

• DOI: 10.1210/jcem.77.5.8077311
• 发表时间: 1993
• 期刊: The Journal of clinical endocrinology and metabolism
• 作者: Mesiano,S;Coulter,CL;Jaffe,RB
• 通讯作者: Jaffe,RB