Research Training in Pediatric Endocrinology

 描述(由申请人提供)：本次竞争续签申请继续支持匹兹堡大学和匹兹堡儿童医院(CHP)的儿科内分泌学和糖尿病博士后研究培训计划。在全国即将出现熟练内分泌研究人员短缺的情况下，目前已进入第20个年头的这项研究培训计划的目标是在儿科内分泌紊乱的细胞、分子、生理、遗传、发育、生化、流行病学、临床和翻译方面提供尖端培训，并让我们的毕业生进入富有成效的学术研究生涯。我们奖学金培训计划的毕业生中有86%是全职学术职位或正在接受额外的培训。该项目的学员是根据以前的学术记录和对学术研究生涯的承诺来选择的，最近申请者的数量和质量都有所增加。该计划需要在临床奖学金培训的第一年之后进行两到三年的指导性研究(基础科学、临床或翻译)。培训人员由在糖尿病、肥胖症、遗传学、发育生物学、生殖轴和核激素受体研究方面具有专业知识的有活力的资助科学家组成。培训教师导师之所以被选中，是因为他们的研究具有高水平和翻译相关性，他们在培训医学博士和博士科学家方面的杰出记录，他们的长期生产力，他们成功地获得外部资金，以及他们对跨学科项目的兴趣。受训者在儿科内分泌科和糖尿病科临床专家的指导下获得临床经验。在研究期间，受训者由受训者选择的一名初级培训导师和一个学术监督委员会(SOC)监督，该委员会监督和评估受训者的科学进步并协助职业发展。所有受训人员都参加负责任的研究培训。定期的评估、授课会议和正式的课程作业为每个学员的科学努力提供了严格的智力基础。该项目的成就、其关键的知识群体、新科长的鼓舞以及CHP和匹兹堡大学的巨大资源使该项目成为培训儿科内分泌内分泌医生和科学家、鼓励他们过渡到K奖项并培养他们作为独立RO1资助的研究人员的成功的杰出项目。基于这些众多的优势，这一研究培训计划提供了一个杰出的机制，通过它，当代医生和研究人员将获得翻译研究中成功和富有成效的学术生涯的基本工具。

 DESCRIPTION (provided by applicant): This competitive renewal applies for continued support for the post-doctoral research training program in pediatric endocrinology and diabetes at the University of Pittsburgh and Children's Hospital of Pittsburgh of UPMC (CHP). With the impending national shortage of skilled physician-investigators, the goal of this research training program, currently in its 20th year, is to provide cutting-edge training in cellular, molecular, physiologic, genetic, developmental, biochemical, epidemiologic, clinical and translational aspects of pediatric endocrine disorders and launch our graduates into productive academic research careers. 86% of the graduates of our fellowship training program are in full-time academic positions or are pursuing additional training. Trainees to the program are selected based on prior academic records and commitment to an academic research career with recent increase in numbers and quality of the applicants. The program entails two to three years of mentored research (basic science, clinical, or translational) beyond the first clinical year of fellowship training. The training faculty consists of dynamic funded scientists with expertise in diabetes, obesity, genetics, developmental biology, reproductive axis and nuclear hormone receptors research. The training faculty mentors are selected because of the high caliber and translational relevance of their research, their outstanding records of training M.D. and Ph.D. scientists, their long-term productivity, their success in securing extramural funding, and their interest in interdisciplinary projects. Trainees gain clinical experience under the supervision of the expert clinical faculty members of the Division of Pediatric Endocrinology and Diabetes. During the research years, the trainees are supervised by a primary training mentor chosen by the trainee and a scholarly oversight committee (SOC) that oversees and evaluates the trainee's scientific progress and assist with career development. All trainees participate in responsible conduct of research training. Regular evaluations, didactic conferences, and formal course work provide a rigorous intellectual foundation for each trainee's scientific endeavors. The achievements of this program, its critical intellectual mass, invigoration by a new division chief and the tremendous resources at the CHP and the University of Pittsburgh make this an outstanding program to train pediatric endocrine physician-scientists, encourage their transition to K awards, and cultivate their success as independent RO1 funded investigators. Based on these numerous strengths, this research training program provides an outstanding mechanism through which contemporary physician- investigators will obtain the tools fundamental for successful and productive academic careers in translational research.