The Ohio State University Center for Clinical and Translational Science

俄亥俄州立大学临床和转化科学中心

• 批准号: 9271092
• 负责人: REBECCA D JACKSON
• 金额: --
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-26 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9271092
• 关键词: Architecture; Biomedical Research; Businesses; Clinical; Clinical Research; Clinical Sciences; Communities; Competence; Development; Discipline; Disease; Ecosystem; Ensure; Environment; Fostering; Foundations; Funding; Health; Home environment; Human; Institution; Instruction; Laboratories; Leadership; Modeling; Ohio; Patient Care; Patient-Focused Outcomes; Prevention; Process; Public Health; Research; Research Infrastructure; Research Methodology; Resource Sharing; Resources; Science; Services; Thinking; Training; Translational Research; Translations; Universities; Vision; career development; clinical care; cohesion; community setting; design; improved; innovation; insight; investigator training; knowledge translation; response; skills

The Ohio State University created the Center for Clinical and Translational Science (CCTS) to catalyze research teams and facilitate innovation through creation of an environment that fosters translation of knowledge to improve human health. The Center will accomplish four specific aims: 1) Build on the unique and diverse strengths of our institution to create an integrated academic home for innovative, team-oriented clinical and translational science; 2) Enhance and nurture the career development of highly trained investigators, with an emphasis on innovation and transdisciplinary science; 3) Integrate and enhance an administrative infrastructure to optimize the efficient conduct of the highest quality, generalizable clinical and translational science that is relevant to the community setting; 4) Develop, enhance and integrate a portfolio of outstanding shared resources in support of transformative clinical and translational research. The CCTS will continue to focus on integrating the traditional biomedical research process (basic scientific discovery with translation to the bedside to dissemination into the community for improved patient outcomes) with a public health model (surveillance to prevention to response). By incorporating this bi-directional model in the creation of a robust translational science infrastructure, the OSU CCTS will foster both the traditional "discovery to best practice" paradigm as well as taking advantage of the insight garnered from our foundation of excellence in clinical care to stimulate basic discovery and clinical research inquiry. The vision and specific aims will be achieved through an integrated model of governance and partnership, home, and leadership for clinical and translational research spanning NCH and OSU; focused pilot funding initiatives for new team development within an innovation ecosystem; unique educational and training architecture which integrates acquisition of core competencies in research methodology, interpretation of results, implementation of findings, design thinking, team leadership skills and business acumen with rigorous discipline-specific laboratory (bench, clinical or community) training; and a clinical and translational science infrastructure that is cohesive, innovative.and adaptable and more effective than the services that currently exist in order to ensure provision of the full range of disease-agnostic scientific resources needed to traverse the continuum of research from T1-4. RELEVANCE (See instructions): The Center for Clinical and Translational Science will improve human health by bringing the benefits of science more quickly into patient care.

俄亥俄州州立大学创建了临床和转化科学中心（CCTS）， 研究团队，并通过创造一个促进翻译的环境来促进创新， 增进人类健康的知识。该中心将实现四个具体目标：1）建立在独特的 和我们机构的多元化优势，为创新，以团队为导向的综合学术家园 临床和转化科学; 2）加强和培养训练有素的职业发展 研究人员，重点是创新和跨学科科学; 3）整合和加强 行政基础设施，以优化最高质量，可推广的临床和 与社区环境相关的转化科学; 4）开发，增强和整合投资组合 优秀的共享资源，以支持变革性的临床和转化研究。持续关连交易 将继续注重整合传统的生物医学研究过程（基础科学发现 从床边到社区传播，以改善患者结局）， 公共卫生模式（监测到预防再到应对）。通过将这种双向模型纳入 创建一个强大的转化科学基础设施，OSU CCTS将促进传统的 “从发现到最佳实践”的范例，以及利用从我们的基金会获得的洞察力 卓越的临床护理，以刺激基础发现和临床研究调查。的远见和 具体目标将通过治理和伙伴关系、家庭和 跨NCH和OSU的临床和转化研究的领导;重点试点资助计划， 创新生态系统中的新团队发展;独特的教育和培训架构， 将核心竞争力的获取整合到研究方法中，解释结果， 实施调查结果，设计思维，团队领导技能和商业头脑， 特定学科的实验室（实验室，临床或社区）培训;以及临床和转化科学 基础设施是有凝聚力的，创新的，适应性强，比目前的服务更有效， 存在，以确保提供全面的疾病不可知的科学资源， 从T1到T4的连续研究。 相关性（参见说明）： 临床和转化科学中心将通过以下方式改善人类健康： 更快地将科学应用到病人护理中。

项目成果

Design, Fabrication, and Administration of the Hand Active Sensation Test (HASTe).

手部主动感觉测试 (HASTe) 的设计、制造和管理。

• DOI: 10.3791/53178
• 发表时间: 2015
• 期刊: Journal of visualized experiments : JoVE
• 作者: Borstad,Alexandra;Altenburger,Alex;Hannigan,Aaron;LaPorte,Joshua;Mott,Rachael;Nichols-Larsen,DeborahS
• 通讯作者: Nichols-Larsen,DeborahS

Intravaginal Practices and Prevalence of Sexual and Reproductive Tract Infections Among Women in Rural Malawi.

• DOI: 10.1097/olq.0000000000000531
• 发表时间: 2016-12
• 期刊: Sexually transmitted diseases
• 影响因子: 3.1
• 作者: Esber A;Rao N;Norris A;Carr Reese P;Kandodo J;Nampandeni P;Jumbe E;Norris Turner A
• 通讯作者: Norris Turner A

Quality or quantity? A multistudy analysis of emotion regulation skills deficits associated with borderline personality disorder.

• DOI: 10.1037/per0000357
• 发表时间: 2019-08
• 期刊: Personality disorders
• 作者: Matthew W. Southward;J. Cheavens

Flexible, yet firm: A model of healthy emotion regulation.

灵活而坚定：健康情绪调节的典范。

• DOI: 10.1521/jscp.2018.37.4.231
• 发表时间: 2018
• 期刊: Journal of social and clinical psychology
• 影响因子: 1.7
• 作者: Southward,MatthewW;Altenburger,ErinM;Moss,SaraA;Cregg,DavidR;Cheavens,JenniferS
• 通讯作者: Cheavens,JenniferS

Transplantation of placenta-derived mesenchymal stem cells enhances angiogenesis after ischemic limb injury in mice.

• DOI: 10.1111/jcmm.12489
• 发表时间: 2016-01
• 期刊: Journal of cellular and molecular medicine
• 影响因子: 5.3
• 作者: Xie N;Li Z;Adesanya TM;Guo W;Liu Y;Fu M;Kilic A;Tan T;Zhu H;Xie X
• 通讯作者: Xie X