The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve Health

俄勒冈州立大学临床和转化科学中心：推进当今的发现以改善健康

• 批准号: 9975951
• 负责人: REBECCA D JACKSON
• 金额: $ 449.71万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-29 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9975951
• 关键词: Address; Adopted; Adoption; Biomedical Research; Child Health; Childhood; Clinic; Clinical Sciences; Collaborations; Communities; Competence; Data; Data Analytics; Data Science; Development; Discipline; Education; Environment; Faculty; Foundations; Goals; Government; Grant; Health; Health system; Individual; Industry; Informatics; Information Dissemination; Institutes; Knowledge; Longevity; Methodology; Methods; Mission; Multi-Institutional Clinical Trial; Ohio; Participant; Pathway interactions; Patients; Pediatric Hospitals; Population; Process; Publications; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Training; Resources; Role; Science; Scientist; Secure; System; Time; Training; Training Programs; Training Support; Training and Education; Translational Research; Translations; Universities; Vision; Work; Workforce Development; base; career; career development; clinical center; college; data sharing; data to knowledge; education resources; improved; innovation; member; novel strategies; programs; research study; skill acquisition; tool; translational approach; translational pipeline

Contact PD/PI: Jackson, Rebecca D OVERVIEW SUMMARY Since our inception, the overarching mission of The Ohio State University’s Center for Clinical and Translational Science (CCTS) has been ambitious: to advance today’s discoveries to improve health. We do this by providing an integrated environment of clinical and translational science (CTS) resources, education, and training pathways and by promoting transformative methodologic advances to catalyze and sustain translational science innovation. In collaboration with our pediatric partner, Nationwide Children’s Hospital, we have developed an aligned vision for translational biomedical science that has been transformative. To continue with our mission, we propose to advance from catalyzing translational science innovation and team science locally to facilitating meaningful clinical and translational science collaborations with community, academic, industry, and government partners and with members of the CTSA Consortium. We will enhance and expand the training, career development, and sustainability of a diverse CTS workforce through the provision of comprehensive, accessible education resources and opportunities (Workforce Development) and engage a broad range of stakeholders as partners in the full spectrum of translational research as active team participants from study inception through dissemination of results (Collaboration and Engagement). We will provide new approaches and resources to enhance inclusion of populations that have traditionally been excluded or studied in isolation and support and enhance studies that span the translational research spectrum by actively reducing barriers to research study participation and catalyzing the translation of discoveries to the clinic and population and across the lifespan (Integration). Moreover, we will promote innovation, quality, and efficiency to advance translational science through an integrated system of translational research resources (Methods and Processes). Finally, we will embed informatics and data analytic solutions across all programs in the OSU-CCTS and across the full spectrum of translational research (Informatics) by integrating and interrogating research data within a secure data environment, develop and adopt innovative methods and tools that facilitate research, and provide a critical foundation in data sciences for the translational science workforce. Over the next 5 years, we will provide a robust research infrastructure and comprehensive research training programs informed by local innovations and strengthened by the adoption of best practices identified by the CTSA Consortium. By leveraging our interdisciplinary scientific strengths, expertise, and perspectives, the OSU-CCTS will catalyze biomedical research translation. With a commitment to experimentation, we will identify gaps and challenges, systematically develop and study (demonstrate) new methods and approaches, and disseminate effective strategies and educational initiatives that will transform clinical and translational science both locally and nationally. Project Summary/Abstract Page 275 Contact PD/PI: Jackson, Rebecca D

联系PD/PI：Jackson，Rebecca D 概述 摘要 自我们成立以来，俄亥俄州立大学临床和医学中心的首要任务是 翻译科学(CCTS)一直雄心勃勃：推进当今的发现，以改善健康。我们 通过提供临床和转化科学(CTS)资源、教育、 和培训途径，并通过促进变革性的方法进步来催化和维持 翻译科学创新。在我们的儿科合作伙伴全国儿童医院的合作下，我们 已经为转译生物医学科学制定了一个一致的愿景，这是革命性的。至 继续我们的使命，我们建议从催化翻译科学创新和团队 促进有意义的临床和翻译科学合作 与社区、学术界、工业界和政府合作伙伴以及CTSA联盟的成员。 我们将加强和扩大多元化CTS员工的培训、职业发展和可持续性 通过提供全面、可获得的教育资源和机会(劳动力 发展)，并让广泛的利益攸关方作为全方位翻译的合作伙伴参与 从研究开始到结果传播，作为积极的团队参与者进行研究(协作和 接洽)。我们将提供新的方法和资源，以加强对有 传统上被排除或孤立地研究，并支持和加强跨越翻译的研究 通过积极减少参与研究的障碍和催化翻译 对临床和人群以及整个生命周期的发现(整合)。此外，我们还将推动 创新、质量和效率通过 翻译研究资源(方法和过程)。最后，我们将嵌入信息学和数据 分析解决方案涉及OSU-CCTS中的所有项目以及翻译研究的全部范围 (信息学)通过在安全的数据环境中集成和询问研究数据，开发和 采用促进研究的创新方法和工具，并为数据科学提供关键基础 对于翻译科学工作者来说。在未来5年，我们将提供强大的研究基础设施 和全面的研究培训计划，以当地创新为信息来源，并由 采用CTSA联盟确定的最佳做法。通过利用我们的跨学科科学 OSU-CCTS的优势、专业知识和视角将促进生物医学研究的翻译。使用一个 致力于实验，我们将找出差距和挑战，系统地开发和研究 (示范)新方法和新途径，传播有效的战略和教育举措 这将改变当地和全国的临床和翻译科学。 项目摘要/摘要页275 联系PD/PI：Jackson，Rebecca D