The Indiana Cutaneous Biological Research Training Program

描述(申请人提供)：这是印第安纳大学医学院(IUSM)支持印第安纳州皮肤生物学研究培训计划(ICBRTP)的修订申请，该计划将侧重于博士后皮肤生物学家的培训。该计划的目标是在基础科学家和临床医生高度互动的跨学科环境中培养博士后实习生，并为他们在皮肤生物学研究中的职业生涯做好准备。一个由10名经验丰富的资深教员组成的团队已经聚集在一起，他们在皮肤相关研究方面有着悠久的历史，作为T32培训计划的导师。这一小组与六名初级教师一起担任顾问教师，创造了一个高效的翻译研究环境。该计划的优势包括一名计划主任和两名副计划主任的领导，这三人都在基础和临床科学方面拥有既定的行政、培训和研究经验，以及导师的质量、研究环境和与皮肤相关的研究的多样性，以及执行“从床到床”研究项目的全面现有资源。ICBRTP的教授和资源教员代表总共九个独立的临床或基础科学系，目前每年有约2700万美元的同行评审直接研究基金。这些导师在培养成功地继续在学术和研究岗位上工作的年轻科学家方面拥有丰富的经验。2名博士后博士后或医学博士实习生需要支持，一个额外的研究员职位将由印第安纳大学皮肤科资助。所有受训人员将参加科学伦理和翻译研究方法方面的课程。授课要求将针对博士后研究员的研究重点进行调整。特定项目的教育/研究活动包括每周皮肤病研究进展会议、基础科学和临床会议以及参加皮肤病研究性学会的年度会议。除了研究之外，受训者还将撰写并提交一份拨款提案。一个由T32计划主任的高级调查人员组成的具体计划指导委员会、由代表其他机构不同培训经验的四名调查人员组成的外部咨询委员会，以及一个由四个步骤组成的计划评估程序已经到位。ICBRTP将加强IUSM的承诺，教育研究人员，他们将发现新的诊断工具，并在开发更有效的皮肤病新疗法方面改变治疗范式。

DESCRIPTION (provided by applicant): This is a revised application from the Indiana University School of Medicine (IUSM) to support the Indiana Cutaneous Biology Research Training Program (ICBRTP), which will focus on the training of postdoctoral cutaneous biologists. The goal of the proposed program is to produce post-doctoral trainees in an interdisciplinary environment of highly interactive basic scientists and clinicians and prepare them for a career in cutaneous biology research. A group of 10 very experienced senior faculty with a long history of skin-related research have been assembled to serve as preceptors for this T32 training program. This group along with six junior faculty serving as resource faculty have created a highly productive translational research environment. Strengths of the program include the leadership of a Program Director and two Associate Program Directors, all three with established administrative, training, and research experience in both basic and clinical science, and the quality of the preceptors, research environment, and diversity of skin-related research, and a full spectrum of existing resources for performing "bench to bedside" research projects. Preceptors and resource faculty of the ICBRTP represent a total of nine separate clinical or basic science departments and currently have ~ $27 million of peer reviewed direct research funds per year. These preceptors have extensive experience in training young scientists who have successfully continued in academic and research positions. Support is requested for 2 post-doctoral PhD or MD trainees, and an additional fellowship position will be funded by the IU Department of Dermatology. All trainees will take courses in scientific ethics and translational research methods. Didactic coursework requirements will be tailored to the research focus of the post-doctoral fellow. Program-specific educational/research events include a weekly Dermatology Research in Progress meeting, basic science and clinical conferences and attendance at the annual Society for Investigative Dermatology Meeting. In addition to research, trainees will write and present a grant proposal. A program- specific Steering Committee comprising senior investigators who are T32 program directors, External Advisory Committee comprising four investigators who represent diverse training experiences at other institutions, and a four-step program evaluation process are in place. ICBRTP will augment the commitment of the IUSM to educate researchers who will discover new diagnostic tools, and alter therapeutic paradigms in the development of new and more efficacious treatments for skin diseases.