Lipid Modulation of Glycine Transporters

甘氨酸转运蛋白的脂质调节

• 批准号: nhmrc : 1030441
• 负责人: A/Pr Renae Ryan
• 金额: $ 24.58万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/lipid-modulation-glycine-transporters/110755
• 关键词: Lipid; Modulation; Glycine; Transporters

Many drugs modulate the function of proteins imbedded in cell membranes. Extensive research has been undertaken to better understand drug interactions with these proteins to improve drug therapies, but there has been relatively little progress in understanding the role of the cell membrane. This project will investigate how the cell membrane influences protein function and then use this information to develop novel drugs for the treatment of neurological disorders.

许多药物调节嵌入细胞膜的蛋白质的功能。已经进行了广泛的研究，以更好地了解药物与这些蛋白质的相互作用，以改善药物治疗，但在了解细胞膜的作用方面进展相对较小。该项目将研究细胞膜如何影响蛋白质功能，然后利用这些信息开发治疗神经系统疾病的新药。