Drug Binding Sites on Glycine Transporters

甘氨酸转运蛋白上的药物结合位点

• 批准号: nhmrc : 571010
• 负责人: A/Pr Renae Ryan
• 金额: $ 33.24万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/drug-binding-sites-glycine-transporters/95062
• 关键词: Drug; Binding; Sites; Glycine; Transporters

Glycine Transporters regulate the concentration of glycine in the spinal cord and brain. It has been suggested that elevating glycine levels in these regions may be useful in treating pain and schizophrenia. This project will provide the basis for the development of new glycine transport inhibitors that may be used to treat these conditions.

甘氨酸转运体调节脊髓和大脑中的甘氨酸浓度。有研究表明，提高这些区域的甘氨酸水平可能有助于治疗疼痛和精神分裂症。该项目将为开发可用于治疗这些疾病的新的甘氨酸转运抑制剂提供基础。