Training in PharmacoNeuroImmune Substance Abuse Research

7.项目摘要/摘要 这是一个跨学科药物滥用研究培训计划的续签申请，该计划的标题是 药物神经免疫学(PNI)药物滥用研究“(T32 DA007097-34)。PNI培训 计划&lt；z.umn.edu/pni&gt；满足了公认的培训生物医学科学家的需求 跨学科和翻译领域的博士后水平，重点是药物之间的相互作用 虐待与神经和免疫系统，并整合了我们对这些生理 与他们的行为同行的互动。培训计划的一个关键组成部分考虑的是 滥用药物是艾滋病毒/艾滋病的共同因素，特别是与神经艾滋病有关。该计划已培训了48名 博士后35人，博士后35人(共83人)。这些人在中国拥有有影响力的职位 学术界、政府和工业界。我们的39名小学教师是一群才华横溢的实验室 在这些学科的交叉领域工作的基础和临床科学家。我们资金雄厚的教职员工 有丰富的导师经验，致力于培养博士后和博士后 在这个跨学科的环境中的研究员。为了用我们现有的资源完成我们的培训任务，我们 申请资助10名博士后和5名博士后。培训成功的所有要素 方案已经到位，并正在高效和有效地运作：一个正式的课程，包括两个核心 神经免疫相互作用和神经心理药理学课程及两场专题讨论会 床边虐待与艾滋病毒/艾滋病：发病机制、治疗和预防。额外的关键培训 活动包括双月系列研讨会、正在进行的研究专题讨论会和年度务虚会。新的 这一应用程序中扩展的PNI培训部分包括：a)增加13名新教师担任教师；b) 开发在线学习模块，供项目实习生和参与 针对多元化学生的相关暑期研究计划；c)发展独特的研究严谨训练 构成部分；以及d)为侧重于非学术领域的博士后研究员发展培训经验 各就各位。明尼苏达大学大力倡导的PNI培训计划得到进一步加强 突出翻译研究，(翻译研究中心)和成瘾的指定为一体 明尼苏达大学AHC的主要研究重点明尼苏达大学的成立证明了这一点 成瘾神经科学中心。强调将成瘾研究作为优先事项， NIDA向调查人员提供研究资金的悠久历史提供了额外的证据，证明 为药物滥用研究的博士后和博士后研究员提供培训的环境。

7. Project Summary/Abstract This is a renewal application for an interdisciplinary Drug Abuse Research Training Program titled “Training in PharmacoNeuroimmunology (PNI) Substance Abuse Research” (T32 DA007097-34). The PNI Training Program <z.umn.edu/pni> meets a well-recognized need to train biomedical scientists at the pre- and postdoctoral levels in an interdisciplinary and translational field that focuses on the interactions of drugs of abuse with the nervous and immune systems, and integrates our understanding of these physiological interactions with their behavioral counterparts. A critical component of the training program considers the role of drugs of abuse as co-factors in HIV/AIDS, specifically relating to NeuroAIDS. The program has trained 48 predoctoral and 35 postdoctoral (83 total) in the past 15 years. These individuals hold influential positions in academia, government, and industry. Our 39 primary faculty preceptors are a talented group of laboratory based and clinical scientists working at these intersections of disciplines. Our well-funded faculty preceptors have extensive experience as mentors and are committed to training predoctoral students and postdoctoral fellows in this interdisciplinary setting. To fulfill our training mission with our available resources, we are requesting funding for 10 predoctoral and 5 postdoctoral slots. All of the elements of a successful training program are in place and are functioning efficiently and effectively: a formal curricula, including the two core courses in Neuro-immune Interactions and Neuropsychopharmacology and two colloquium in Substance Abuse at the Bedside and HIV/AIDS: Pathogenesis, Treatment, and Prevention. Additional critical training activities include a bimonthly seminar series, a research-in-progress symposium, and a yearly retreat. The new expanded PNI training components in this application include: a) adding 13 new faculty as preceptors; b) developing online learning modules for use by program trainees and undergraduate students participating in the linked summer research program for students of diversity; c) developing a unique research rigor training component; and d) developing a training experience for postdoctoral fellows focused on nonacademic positions. The PNI training program is further enhanced by the University of Minnesota strong initiative to highlight translational research, (Center for Translational Research) and the designation of Addiction as one major research priority by the AHC, University of Minnesota evidenced by the establishment of Minnesota Center for Addiction Neuroscience MNCAN. The emphasized commitment to addiction research as a priority, and the long standing history of research funding to investigators by NIDA provide additional evidence of a rich environment for the training of pre and postdoctoral research fellows in substance abuse research.