TRAINING IN PSYCHONEUROIMMUNOLOGY AND SUBSTANCE ABUSE

心理神经免疫学和药物滥用培训

• 批准号: 2897842
• 负责人: THOMAS William MOLITOR
• 金额: $ 42.95万
• 依托单位: HENNEPIN HEALTHCARE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-07-01 至 2001-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2897842
• 关键词: TRAINING; PSYCHONEUROIMMUNOLOGY; SUBSTANCE; ABUSE

APPLICANT'S ABSTRACT: This is an application for competitive renewal of a training grant in Psychoneuroimmunology and Substance Abuse. The central principle underlying the proposed program is that progress toward understanding the interactions between substances of abuse and the nervous and immune systems, and the role of these interactions in the pathogenesis of HIV, requires the training of young, bright scientists (pre- and post- doctoral students) in this highly interdisciplinary field. The training emphasizes mastery of the interdisciplinary knowledge base and research methodologies which are essential to this emerging field of investigation. Understanding the impact of drug abuse on the brain immune axis will be the goal of the training. To accomplish this, the educational structure includes a formal pre-doctoral curriculum in Psychoneuroimmunology and Substance Abuse, a declared graduate school minor in Psychoneuroimmunology, a formal course in Neuro-immune Interactions, an active seminar and conference schedule and research linkages with faculty across the relevant disciplines. The primary training faculty includes scientists with M.D. and/or Ph.D. degrees in neuroendocrinology, neuroscience, medicinal chemistry, infectious diseases, psychology and immunology who are conversant with a wide array of research methodologies. The faculty will be able to train individuals in this interdisciplinary field, from physiological, pathobiological and medical perspectives. In addition to the acquisition of knowledge and analytical skills, the training program will emphasize research in laboratory-based Psychoneuroimmunology and Substance Abuse, sponsored by one primary and one secondary trainer who represent complementary scientific disciplines central to the field of Psychoneuroimmunology and Substance Abuse. As a result of its organization, curriculum, tutorials, and interdisciplinary research environment, this training program will develop scientists who have both the knowledge and direct experience necessary to continue active research careers in the field of Psychoneuroimmunology and Substance Abuse. To date, five pre-doctoral students have been admitted to the training program over the past three years and the first student will graduate in nine months. The success of past training and a significant applicant pool of candidates points to the need for additional positions. We request in this grant nine pre-doctoral positions, and increase of four over the previous grant, for the next five years. Sixteen post-doctoral trainees have been admitted to the program. Six have completed training, and hold positions with academic and research institutions. We request ten post-doctoral positions, which would maintain the current number of positions. Thus, the program is successfully developing biomedical scientists with the knowledge and experience which enables them to continue research on Psychoneuroimmunoloy and Substance Abuse.

申请人摘要：这是一份关于精神神经免疫学和物质滥用培训补助金竞争性更新的申请。拟议方案的核心原则是，要想了解滥用药物与神经和免疫系统之间的相互作用以及这些相互作用在艾滋病毒发病机制中的作用，就需要在这一高度跨学科的领域培养年轻、聪明的科学家（博士前和博士后）。培训强调掌握跨学科的知识基础 和研究方法，这是必不可少的调查这一新兴领域。 了解药物滥用对大脑免疫轴的影响将是培训的目标。为了实现这一目标，教育结构包括心理神经免疫学和药物滥用的正式博士前课程，心理神经免疫学的宣布研究生院未成年人，神经免疫相互作用的正式课程，积极的研讨会和会议时间表以及与相关学科教师的研究联系。 初级培训教师包括具有医学博士学位的科学家。和/或博士神经内分泌学、神经科学、药物化学、传染病、心理学和免疫学学位，熟悉各种研究方法。教师将能够培养个人在这个跨学科领域，从生理学，病理生物学和医学的角度。除了获得知识和分析技能外，培训方案还将强调以实验室为基础的心理神经免疫学和药物滥用研究，由一名初级和一名中级培训员赞助，他们代表互补的 心理神经免疫学和药物滥用领域的核心科学学科。由于其组织，课程，教程和跨学科研究环境的结果，该培训计划将培养具有继续在心理神经免疫学和药物滥用领域积极研究事业所需的知识和直接经验的科学家。到目前为止，在过去的三年里，已经有五名博士前学生被录取参加培训计划，第一名学生将在九个月内毕业。过去的培训取得成功，而且申请者众多，这表明需要增设职位。我们要求在此授予九个博士前职位，并增加四个比以前的补助金，在未来五年。16名博士后已被录取。6人已完成培训，并在学术和研究机构任职。我们申请10个博士后职位，这将保持目前的职位数量。 因此，该计划正在成功地培养具有知识和经验的生物医学科学家，使他们能够继续研究心理神经免疫学和药物滥用。

项目成果

Altered white matter microstructure in adolescents with major depression: a preliminary study.

• DOI: 10.1097/00004583-201002000-00011
• 发表时间: 2010-02
• 期刊: Journal of the American Academy of Child and Adolescent Psychiatry
• 影响因子: 13.3
• 作者: Cullen KR;Klimes-Dougan B;Muetzel R;Mueller BA;Camchong J;Houri A;Kurma S;Lim KO
• 通讯作者: Lim KO

A Brain in a Dish.

盘子里的大脑。

• 发表时间: 2015
• 期刊: Postdoc journal : a journal of postdoctoral research and postdoctoral affairs
• 作者: Goodwin,ShikhaJain

Changes in resting functional connectivity during abstinence in stimulant use disorder: a preliminary comparison of relapsers and abstainers.

• DOI: 10.1016/j.drugalcdep.2014.03.024
• 发表时间: 2014-06-01
• 期刊: DRUG AND ALCOHOL DEPENDENCE
• 影响因子: 4.2
• 作者: Camchong, Jazmin;MacDonald, Angus W., III;Mueller, Bryon A.;Nelson, Brent;Specker, Sheila;Slaymaker, Valerie;Lim, Kelvin O.
• 通讯作者: Lim, Kelvin O.

Defining the cognitive enhancing properties of video games: Steps Towards Standardization and Translation.

定义视频游戏的认知增强特性：迈向标准化和翻译的步骤。

• DOI: 10.14304/surya.jpr.v4n9.5
• 发表时间: 2016
• 期刊: Postdoc journal : a journal of postdoctoral research and postdoctoral affairs
• 作者: Goodwin,ShikhaJain;Dziobek,Derek
• 通讯作者: Dziobek,Derek

Altered resting state complexity in schizophrenia.

• DOI: 10.1016/j.neuroimage.2011.10.002
• 发表时间: 2012-02-01
• 期刊: NEUROIMAGE
• 影响因子: 5.7
• 作者: Bassett, Danielle S.;Nelson, Brent G.;Mueller, Bryon A.;Camchong, Jazmin;Lim, Kelvin O.
• 通讯作者: Lim, Kelvin O.