Predoctoral Training Program in Trans-Disciplinary Pharmacological Sciences

 描述（由申请人提供）：跨学科药理学的博士前培训计划这是一个应用程序的重新提交，继续现有的跨学科药理学的博士前培训计划（T32）在分子药理学和生理学（MPP）研究生课程在布朗大学。在第一个周期（2010-2015年），培训补助金资助了13名博士前学员。这一更新申请要求每年资助4名博士前学员，为期5年，并打算资助第二年和第三年学习的学员。该培训计划旨在培养能够在跨学科领域建立杰出独立研究的毕业生，为现代药理学做出贡献。T32已经在这个小的，发展中的研究生课程中产生了几个重大的改进，并对生物与医学系和大学产生了积极的影响。该培训项目有33名来自布朗大学及其沃伦阿尔珀特医学院几个系的优秀教员培训员。培训教师的研究生产力，资金和指导记录是强大的，有许多合作互动，使学员受益。该计划中培训师的研究领域分为五大类：1）分子结构及其在疾病中的作用; 2）神经药理学和神经回路功能; 3）受体和通道药理学，生理学和信号转导; 4）翻译和临床应用;和5）化学生物学及其应用。受训者获得职业技能 通过课程作业，实验室轮换，以及许多相互科学互动的机制，并与教师培训人员，以及布朗以外的科学家，在药理学领域的熟练程度。研究生项目主任，培训补助PI，研究生项目委员会，论文顾问和论文委员会以及布朗的研究生和博士后研究办公室提供了广泛的咨询和评估。学员还通过MPP研究生课程内外赞助的课程接触到各种职业道路。我们几乎没有自然减员，我们的毕业生有出色的职业成果。该计划致力于招募和留住所有种族和社会经济背景的学生，迄今为止取得了巨大的成功-该计划通常由约40%代表性不足的少数民族组成，包括非洲裔美国人，西班牙裔和美洲原住民。继续资助跨学科药理学博士前培训计划将使我们能够继续设计新的方法，目标是使科学界的优秀成员毕业，掌握开发新药和治疗方法所必需的技能。

 DESCRIPTION (provided by applicant): Predoctoral Training Program in Trans-Disciplinary Pharmacological Sciences This is the resubmission of an application to continue the existing Predoctoral Training Program in Trans- Disciplinary Pharmacological Sciences (T32) within the Molecular Pharmacology and Physiology (MPP) Graduate Program at Brown University. In its first cycle (2010-2015), the training grant funded 13 predoctoral trainees. This renewal application requests funding for 4 predoctoral trainees per year for 5 years and is intended to fund trainees in their second and third years of study. The training program is designed to produce graduates capable of establishing outstanding independent research in the interdisciplinary fields contributing to modern pharmacological sciences. The T32 already has produced several major improvements in this small, developing graduate program, with positive effects extending to the Division of Biology & Medicine and the University. The training program has 33 outstanding faculty trainers drawn from several departments at Brown University and its Warren Alpert Medical School. The research productivity, funding and mentoring records of the training faculty are strong, and there are many collaborative interactions that benefit the trainees. The research areas of trainers within the program fall into five broad categories: 1) molecular structure and its role in disease; 2) neuropharmacology and neural circuit function; 3) receptor and channel pharmacology, physiology and signal transduction; 4) translational and clinical applications; and 5) chemical biology and its applications. Trainees acquire career skills and proficiency in the areas of pharmacology through coursework, lab rotations, and many mechanisms for scientific interaction with each other and with faculty trainers, as well as with scientists from outside Brown. There is extensive advising and evaluation by the Graduate Program Director, Training Grant PI, Graduate Program Committee, Thesis Advisors and Thesis Committees, as well as by Brown's Office of Graduate and Postdoctoral Studies. Trainees also are exposed to a variety of career paths through programs sponsored within and outside the MPP graduate program. We have almost no attrition, and our graduates have outstanding career outcomes. The program strives to recruit and retain students of all ethnicities and socioeconomic backgrounds, and has great success to-date -- the program typically consists of ~40% underrepresented minorities, including African-American, Hispanic and Native American. Continued funding of the Predoctoral Training Program in Trans-Disciplinary Pharmacological Sciences will allow us to continue to design new methods with the goal of graduating outstanding members of the scientific community with the skills essential to developing new drugs and therapeutics.