Hotspots: Understanding Areas of Concentrated Alcohol and Drug Problems at the US-Mexico Border
Hotspots: Understanding Areas of Concentrated Alcohol and Drug Problems at the US-Mexico Border
批准号:
9228313
负责人:
SARAH E. ZEMORE
金额:
$22.05万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AddressAgeAlcohol abuseAlcohol consumptionAlcohol or Other Drugs useAlcoholsAreaAutomobile DrivingBorder CrossingsBuffersCitiesCrimeDataData SetDevelopmentDisadvantagedDrug usageEcologyEnvironmentEnvironmental Risk FactorEpidemiologyExposure toFamilyFibrinogenFriendsGenderGrantHealthHispanicsHouseholdImmigrantImmigrationIndividualInsuranceInterventionInterviewLanguageLatinoLaw EnforcementLightLocationMexicanMexican AmericansMexicoModelingNeighborhoodsOccupationsOutcomePaperPathway interactionsPatternPersonsPharmaceutical PreparationsPlayPopulationPrivatizationProbability SamplesProcessPsychological FactorsResearchResourcesRiskRisk FactorsRoleSamplingServicesSisterSiteStagingSurveysTestingTexasVariantViolencealcohol epidemiologyalcohol related problemalcohol riskbasecomparativedensityepidemiology studyfamily supportgeographic differenceimprovedknowledge basemigrationprogramssocioeconomic disadvantagesubstance abuse epidemiologytrafficking
中文摘要
摘要:热点:了解美国集中酒精和毒品问题的领域-
墨西哥边境
数以百万计的墨西哥裔美国人生活在美墨边境地区,这两个地区都处于极其不利的地位
区域和向内陆迁徙的中转区。因此,墨西哥人的健康和物质使用模式-
原籍边界居民是最令人关切的。尽管如此,尽管初步证据表明
在边境的贩运、毒品供应和药物使用问题上,人们对酒精知之甚少
以及这一地区的毒品问题。我们的团队最近启动了一项大型流行病学研究,美国-墨西哥
酒精及相关条件研究,或UMSARC(R01AA018365;Pi‘s CherPitel and Borges),以解决
这个缺口。除了是仅有的两项大规模的边境流行病学研究之一
UMSARC是已知的唯一一项对美国和墨西哥居民进行调查的此类研究。数据
代表4796人与墨西哥人和墨西哥裔人的可能样本进行面谈
在2011-2013年间接受采访。基于UMSARC数据的新兴论文表明,
酒精和毒品问题,但在美国边境,物质使用治疗利用率大幅下降,
与内地相比。然而,初步证据也表明,即使在
边境地区,酒精和毒品问题集中在美国的一个热点:德克萨斯州的拉雷多。
未发表的初步分析还指出,拉雷多的姊妹城市新拉雷多是毒品的热点
有问题。这表明,当地环境可能在酒精和药物结果中发挥关键作用
边境--也许在整个拉美裔中也是如此。对环境的作用有更深的认识
边境热点问题明显集中的因素将有助于揭示核心流程
在药物滥用的流行病学中,以及与拉丁美洲有关的可能的干预点
边境地区和更广泛的地区。然而,还需要更多的研究来1)更好地描述和
将UMSARC站点在酒精和药物相关结果中的差异与背景联系起来;2)描述
解释这种变异的特定环境(和其他)因素;以及3)更好地理解
美国和墨西哥之间的影响,以及美墨互动可能如何促进
有问题。目前的项目建议解决这些差距。目标1将更好地描述分布
酒精使用和问题,药物使用和问题,以及药物使用治疗利用的研究
并与区域和国家估计数相比较。目标2和3将涉及对数据进行地理编码以测试角色
寻找关键的邻居变量来解释与酒精和毒品相关的结果的地理差异。目标
4将直接探索墨西哥和美国之间的潜在影响途径,使用现有的和地理编码
变量。分析将利用独特的丰富且功能强大的数据集来扩展非常有限的
关于酒精和毒品使用以及边境问题的知识库,以及提高对
环境对拉丁裔人口的这些结果的影响。
英文摘要
ABSTRACT: Hotspots: Understanding Areas of Concentrated Alcohol and Drug Problems at the US-
Mexico Border
Millions of Mexican Americans live in the US-Mexico border region, which is both an extremely disadvantaged
area and a staging zone for migration to the interior. Thus, the health and substance use patterns of Mexican-
origin border residents are of central concern. Nevertheless, despite preliminary evidence of high drug
trafficking, drug availability, and substance use problems along the border, very little is known about alcohol
and drug problems in this area. Our team recently initiated a large epidemiological study, the US-Mexico
Study of Alcohol and Related Conditions, or UMSARC (R01AA018365; PI's Cherpitel and Borges), to address
this gap. In addition to being one of only two large-scale epidemiological studies of the border addressing
alcohol, UMSARC is the only known such study to survey residents of both the US and Mexico. Data
represent 4,796 in-person interviews with a probability sample of Mexican and Mexican-origin individuals
interviewed between 2011-2013. Emerging papers based on UMSARC data suggest a heightened risk for
alcohol and drug problems, yet substantially lower substance use treatment utilization, at the US border,
compared to the interior. Yet, preliminary evidence also suggests dramatic, unexplained variation even among
border sites, with alcohol and drug problems being concentrated in a single US hotspot: Laredo, Texas.
Preliminary, unpublished analyses also point to Nuevo Laredo, Laredo's sister city, as a hotspot for drug
problems. This suggests that the local environment may play a critical role in alcohol and drug outcomes at
the border—and perhaps among Latinos generally. A deeper understanding of the role of environmental
factors in this apparent concentration of problems in border hotspots would help shed light on core processes
in the epidemiology of substance abuse as well as possible points of intervention relevant to Latinos in the
border region and more broadly. However, additional research is needed to 1) better characterize and
contextualize variation across UMSARC sites in alcohol- and drug-related outcomes; 2) delineate the roles of
specific environmental (and other) factors in explaining this variation; and 3) better understand pathways of
influence between the US and Mexico, and how US-Mexico interactions may contribute to elevations of
problems. The current project proposes to address these gaps. Aim 1 will better characterize the distribution
of alcohol use and problems, drug use and problems, and substance use treatment utilization across study
sites and relative to regional and national estimates. Aims 2 and 3 will involve geocoding the data to test roles
for key neighborhood variables in explaining geographic variation in alcohol- and drug- related outcomes. Aim
4 will directly explore potential pathways of influence between Mexico and the US using existing and geocoded
variables. Analyses will leverage a uniquely rich and well-powered dataset to extend the very limited
knowledge base on alcohol and drug use and problems at the border, as well as improve understanding of
environmental influences on these outcomes among Latino populations.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mutual Help Alternatives for Alcohol Problems: Benefits and Causal Mechanisms
-
批准号:10413241
-
项目类别:
-
资助金额:$36.05万
-
财政年份:2020
-
负责人:SARAH E. ZEMORE
-
依托单位:
Mutual Help Alternatives for Alcohol Problems: Benefits and Causal Mechanisms
-
批准号:10627918
-
项目类别:
-
资助金额:$36.05万
-
财政年份:2020
-
负责人:SARAH E. ZEMORE
-
依托单位:
Mutual Help Alternatives for Alcohol Problems: Benefits and Causal Mechanisms
-
批准号:10249057
-
项目类别:
-
资助金额:$36.05万
-
财政年份:2020
-
负责人:SARAH E. ZEMORE
-
依托单位:
12-step Alternatives and Recovery Outcomes in a Large National Study
-
批准号:8924892
-
项目类别:
-
资助金额:$21.52万
-
财政年份:2014
-
负责人:SARAH E. ZEMORE
-
依托单位:
12-step Alternatives and Recovery Outcomes in a Large National Study
-
批准号:8787902
-
项目类别:
-
资助金额:$18.32万
-
财政年份:2014
-
负责人:SARAH E. ZEMORE
-
依托单位:
Developing a New Scale of Treatment Readiness
-
批准号:7386947
-
项目类别:
-
资助金额:$25.68万
-
财政年份:2008
-
负责人:SARAH E. ZEMORE
-
依托单位:
Developing a New Scale of Treatment Readiness
-
批准号:7653869
-
项目类别:
-
资助金额:$14.28万
-
财政年份:2008
-
负责人:SARAH E. ZEMORE
-
依托单位:
Acculturation and Alcohol among U.S. Latinas
-
批准号:7229832
-
项目类别:
-
资助金额:$17.73万
-
财政年份:2005
-
负责人:SARAH E. ZEMORE
-
依托单位:
Acculturation and Alcohol among U.S. Latinas
-
批准号:7014955
-
项目类别:
-
资助金额:$22.11万
-
财政年份:2005
-
负责人:SARAH E. ZEMORE
-
依托单位:
Pilot Studies
-
批准号:8977968
-
项目类别:
-
资助金额:$13.23万
-
财政年份:--
-
负责人:SARAH E. ZEMORE
-
依托单位:
国内基金
海外基金
登录
查看更多内容
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
-
批准号:JCZRLH202601523
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
芹菜素通过AGE-RAGE通路抑制干眼的炎症与氧化应激
-
批准号:82505677
-
项目类别:青年科学基金项目(C类)
-
资助金额:30.00万元
-
批准年份:2025
-
负责人:吕雨霏
-
依托单位:
麝香通心滴丸通过干预AGE-RAGE轴调节O-GlcNAc修饰发挥防治DCM作用的药效物质及机制研究
-
批准号:82574874
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2025
-
负责人:刘天华
-
依托单位:
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
-
批准号:JCZRQN202500010
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:
-
依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
-
批准号:2025JJ70209
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:雷芬芳
-
依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
-
批准号:--
-
项目类别:面上项目
-
资助金额:--
-
批准年份:2024
-
负责人:万荣
-
依托单位:
甜茶抑制AGE-RAGE通路增强突触可塑性改善小鼠抑郁样行为
-
批准号:2023JJ50274
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2023
-
负责人:贺志明
-
依托单位:
蒙药额尔敦-乌日勒基础方调控AGE-RAGE信号通路改善术后认知功能障碍研究
-
批准号:--
-
项目类别:地区科学基金项目
-
资助金额:33万元
-
批准年份:2022
-
负责人:都义日
-
依托单位:
补肾健脾祛瘀方调控AGE/RAGE信号通路在再生障碍性贫血骨髓间充质干细胞功能受损的作用与机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:52万元
-
批准年份:2022
-
负责人:叶宝东
-
依托单位:
LncRNA GAS5在2型糖尿病动脉粥样硬化中对AGE-RAGE 信号通路上相关基因的调控作用及机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2022
-
负责人:于海兵
-
依托单位: