Global HIV Implementation Science Research Training Grant

描述(申请人提供)：虽然艾滋病毒流行的规模仍然很大，但它已经进入了一个充满希望的新阶段，标志着前所未有的进展和机遇。鉴于需要严格测试干预措施，以改进对最新科学发现的理解、实施和转化为护理标准(知识差距)，以及评估将此类干预措施规模化的影响，我们建议启动一项新的研究培训计划，重点是全球艾滋病毒实施科学。实施科学是对促进将研究结果和循证干预措施纳入卫生保健政策和实践，从而提高卫生服务质量和有效性的方法的科学研究。作为翻译研究的关键要素，实施科学包括广泛的技能，包括流行病学、生物统计学、卫生经济学、决策科学和社会学。拟议的培训计划的目标是使合格的个人为独立资助的研究人员的职业生涯和在全球艾滋病毒实施研究中的领导做好准备。我们汇聚了一批来自哥伦比亚大学和海外多所学校、系和中心的不同教职员工，他们在导师指导方面表现突出，是针对关键人群中艾滋病毒预防、与护理的联系和保留、预防母婴传播以及结核病/艾滋病毒整合的前沿实施研究。培训计划将包括基于个性化培训计划的精简课程；每周教员与受训人员研讨会；量身定做的指导；在各种国内和国际实地环境中的研究经验；演讲；手稿和赠款准备；研究研讨会和座谈会；以及负责任的研究行为指导。培训计划还将包括对培训计划的质量和有效性的严格评估，以确保受训人员具备作为未来艾滋病毒实施科学研究领导者所需的能力和技能。这项为期五年的计划旨在一次支持7名(3名博士后和4名博士后)实习生。在博士后实习生中，将寻求拥有博士、博士和医学博士学位的实习生。博士前培训生将被要求攻读流行病学博士学位。博士后候选人的支持期为三年，博士后候选人的支持期为两年。凭借一流的教师队伍、独特的培训环境以及在国内和国际领域无与伦比的研究机会，我们已做好准备，领导这一新颖的努力，培养受过多维、跨学科方法培训的新调查人员，以促进科学知识并展示干预措施的影响。

DESCRIPTION (provided by applicant): While the scale of the HIV epidemic remains large, it has entered a promising new phase, marked by unprecedented progress and opportunities. In view of the need to rigorously test interventions to improve the uptake, implementation, and translation of recent scientific findings into standard of care (the know-do gap), as well as to evaluate the impact of bringing such interventions to scale, we propose to launch a new research training program focused on Global HIV Implementation Science. Implementation science is the scientific study of methods to promote integration of research findings and evidence-based interventions into health care policy and practice, thus improving the quality and effectiveness of health services. A key element of translational research, implementation science encompasses a broad range of skills, including epidemiology, biostatistics, health economics, decision science, and sociology. The goal of the proposed Training Program is to prepare well qualified individuals for careers as independently-funded researchers and for leadership in global HIV implementation research. We have assembled an outstanding group of diverse faculty from multiple schools, departments, and centers at Columbia University and abroad who have distinguished themselves in mentorship and are leading cutting edge implementation research addressing HIV prevention among key populations, linkage to and retention in care, prevention of mother to child transmission, and TB/HIV integration. The Training Program will encompass streamlined coursework based on an individualized training plan; weekly faculty-trainee seminars; tailored mentorship; research experience in a variety of domestic and international field settings; presentations; manuscript and grant preparation; research seminars and colloquia; and instruction in the responsible conduct of research. The Training Program will also include rigorous evaluation of the quality and effectiveness of the Training Program, to ensure that trainees achieve the competencies and skills necessary for success as future leaders in HIV implementation science research. The five-year program aims to support seven (three predoctoral and four postdoctoral) trainees at any one time. Among the postdoctoral trainees, a mix of trainees with PhD, DrPH, and MD degrees will be sought. Predoctoral trainees will be required to pursue a doctoral degree in Epidemiology. The period of support will be three years for predoctoral candidates and two years for postdoctoral candidates. With stellar faculty, a unique training environment, and unparalleled research opportunities in domestic and international field settings, we are well-poised to lead this novel effort and nurture new investigators trained in multidimensional, interdisciplinary approaches to advance scientific knowledge and demonstrate the impact of interventions.