Global HIV Implementation Science Research Training Grant

描述（由申请人提供）：虽然艾滋病毒流行病的规模仍然很大，但它已经进入了一个充满希望的新阶段，其标志是前所未有的进展和机遇。鉴于有必要严格测试干预措施，以提高对最新科学发现的吸收、实施和转化为标准护理（知识差距），并评估将此类干预措施规模化的影响，我们建议启动一项新的研究培训计划，重点关注全球艾滋病毒实施科学。实施科学是对促进将研究成果和循证干预措施纳入卫生保健政策和实践，从而提高卫生服务质量和有效性的方法的科学研究。作为转化研究的一个关键要素，实施科学涵盖了广泛的技能，包括流行病学、生物统计学、卫生经济学、决策科学和社会学。拟议的培训计划的目标是为成为独立资助的研究人员和领导全球艾滋病毒实施研究的合格人员做好准备。我们汇集了来自哥伦比亚大学和国外多个学院、院系和中心的优秀教师，他们在指导方面表现出色，并在解决关键人群的艾滋病毒预防、与护理的联系和保留、预防母婴传播以及结核病/艾滋病毒整合等问题上引领前沿实施研究。培训计划将包括基于个性化培训计划的精简课程；每周教师见习研讨会；定制的指导;具有国内外多个领域的研究经验；演示文稿;稿件和拨款准备；研究研讨会和座谈会；以及负责任的研究指导。该培训计划还将包括对培训计划的质量和有效性进行严格评估，以确保受训人员获得成功成为未来艾滋病毒实施科学研究领导者所需的能力和技能。该计划为期五年，旨在同时支持7名（3名博士预科生和4名博士后）实习生。在博士后受训者中，将寻求具有博士学位、博士学位和医学博士学位的受训者。博士预科生必须攻读流行病学博士学位。资助期限为博士预科生3年，博士后2年。凭借一流的师资队伍，独特的培训环境，以及国内和国际领域无与伦比的研究机会，我们已经准备好引领这一新的努力，培养新的研究人员，他们接受了多维、跨学科方法的培训，以推进科学知识和展示干预措施的影响。

DESCRIPTION (provided by applicant): While the scale of the HIV epidemic remains large, it has entered a promising new phase, marked by unprecedented progress and opportunities. In view of the need to rigorously test interventions to improve the uptake, implementation, and translation of recent scientific findings into standard of care (the know-do gap), as well as to evaluate the impact of bringing such interventions to scale, we propose to launch a new research training program focused on Global HIV Implementation Science. Implementation science is the scientific study of methods to promote integration of research findings and evidence-based interventions into health care policy and practice, thus improving the quality and effectiveness of health services. A key element of translational research, implementation science encompasses a broad range of skills, including epidemiology, biostatistics, health economics, decision science, and sociology. The goal of the proposed Training Program is to prepare well qualified individuals for careers as independently-funded researchers and for leadership in global HIV implementation research. We have assembled an outstanding group of diverse faculty from multiple schools, departments, and centers at Columbia University and abroad who have distinguished themselves in mentorship and are leading cutting edge implementation research addressing HIV prevention among key populations, linkage to and retention in care, prevention of mother to child transmission, and TB/HIV integration. The Training Program will encompass streamlined coursework based on an individualized training plan; weekly faculty-trainee seminars; tailored mentorship; research experience in a variety of domestic and international field settings; presentations; manuscript and grant preparation; research seminars and colloquia; and instruction in the responsible conduct of research. The Training Program will also include rigorous evaluation of the quality and effectiveness of the Training Program, to ensure that trainees achieve the competencies and skills necessary for success as future leaders in HIV implementation science research. The five-year program aims to support seven (three predoctoral and four postdoctoral) trainees at any one time. Among the postdoctoral trainees, a mix of trainees with PhD, DrPH, and MD degrees will be sought. Predoctoral trainees will be required to pursue a doctoral degree in Epidemiology. The period of support will be three years for predoctoral candidates and two years for postdoctoral candidates. With stellar faculty, a unique training environment, and unparalleled research opportunities in domestic and international field settings, we are well-poised to lead this novel effort and nurture new investigators trained in multidimensional, interdisciplinary approaches to advance scientific knowledge and demonstrate the impact of interventions.