In Vivo Experience with NRT to Increase Adherence and Smoking Abstinence

使用 NRT 提高依从性和戒烟率的体内经验

基本信息

  • 批准号:
    9324175
  • 负责人:
  • 金额:
    $ 51.39万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-08-01 至 2021-05-31
  • 项目状态:
    已结题

项目摘要

 DESCRIPTION (provided by applicant): Smoking remains the leading cause of death and disability in the United States, resulting in death for 1 out of every 2 smokers. While smoking rates have declined to about 18% among the general population, smoking rates still remain disproportionately high among individuals in the criminal justice system (i.e., 70-80%). Despite this high rate of smoking, few interventions have been tested in this population. We were the first to investigate providing 12 weeks of bupropion to a sample of community corrections smokers and then randomizing them to either four sessions of smoking cessation counseling or no counseling to quit. No significant differences were found between our two groups, indicating no additional benefit from more intensive smoking cessation counseling. However, while only 5.8% were abstinent at the 6 month follow-up, abstinence rates were quadrupled among the minority of those who were adherent to medication. Developing interventions to increase medication adherence has been cited as the most important means to reducing disparities; however, the few interventions that have investigated increasing adherence have been psychoeducational only and have yielded poor results. But evidence from our previous work demonstrated that smokers who had previous experience using bupropion had higher subsequent cessation rates and this relationship was mediated by improved medication adherence. Thus, exposure to medication is very likely the critical factor in improving subsequent adherence. The current application proposes a randomized controlled trial to maximize medication adherence with this population of smokers by testing an In Vivo NRT experiential intervention. Participants randomized to the In Vivo intervention will try a nicotine patch in Session 1, try nicotine gum in Session 2, try combination nicotine replacement therapy (cNRT) in Session 3, and discuss any problems with use of cNRT for a quit attempt in Session 4. During each 30-minute session they will discuss their expectations for the medication as well as the In Vivo session effects of these medications on withdrawal symptomatology, including urge to smoke. Between sessions, participants will be given medication to use during that week to make practice quit attempts and to become familiar with the medication. Participants randomized to the control group will receive four 30-minute sessions of standard behavioral counseling. All participants will receive cNRT for 10 weeks. Follow-ups will occur up to six months post-intervention. Primary outcomes include 6 month point prevalence abstinence and abstinence across time as well as medication adherence. If successful, this intervention could provide an easily transportable, novel, and tailored intervention to increase medication adherence and improve smoking cessation rates among smokers in the criminal justice system to reduce health disparities and save lives.


项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Karen L Cropsey其他文献

Predictors of MOUD referral among persons with involvement in the criminal legal system.
MOUD 向涉及刑事法律系统的人员转介的预测因素。
  • DOI:
    10.5055/jom.0831
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Andrew P. Bontemps;Sofía Mildrum Chana;Elizabeth S Hawes;Yoser Al Rawi;Christina E Cenczyk;Lindsey R Atkins;Li Li;Karen L Cropsey
  • 通讯作者:
    Karen L Cropsey

Karen L Cropsey的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Karen L Cropsey', 18)}}的其他基金

Medications for opioid use disorder differentially modulate intrinsically photosensitive retinal ganglion cell function, sleep, and circadian rhythms: implications for treatment
治疗阿片类药物使用障碍的药物差异调节本质光敏性视网膜神经节细胞功能、睡眠和昼夜节律:对治疗的影响
  • 批准号:
    10783274
  • 财政年份:
    2023
  • 资助金额:
    $ 51.39万
  • 项目类别:
Admin Core
管理核心
  • 批准号:
    10303937
  • 财政年份:
    2021
  • 资助金额:
    $ 51.39万
  • 项目类别:
Zambia Alabama HIV Alcohol Comorbidities Program (ZAMBAMA)
赞比亚阿拉巴马州艾滋病毒酒精合并症计划 (ZAMBAMA)
  • 批准号:
    10685452
  • 财政年份:
    2021
  • 资助金额:
    $ 51.39万
  • 项目类别:
Zambia Alabama HIV Alcohol Comorbidities Program (ZAMBAMA)
赞比亚阿拉巴马州艾滋病毒酒精合并症计划 (ZAMBAMA)
  • 批准号:
    10303936
  • 财政年份:
    2021
  • 资助金额:
    $ 51.39万
  • 项目类别:
Admin Core
管理核心
  • 批准号:
    10685454
  • 财政年份:
    2021
  • 资助金额:
    $ 51.39万
  • 项目类别:
Circadian and sleep mechanisms among racial groups for nicotine dependence, craving, and withdrawal
不同种族群体对尼古丁依赖、渴望和戒断的昼夜节律和睡眠机制
  • 批准号:
    10206083
  • 财政年份:
    2020
  • 资助金额:
    $ 51.39万
  • 项目类别:
Circadian and sleep mechanisms among racial groups for nicotine dependence, craving, and withdrawal
不同种族群体对尼古丁依赖、渴望和戒断的昼夜节律和睡眠机制
  • 批准号:
    10393609
  • 财政年份:
    2020
  • 资助金额:
    $ 51.39万
  • 项目类别:
Circadian and sleep mechanisms among racial groups for nicotine dependence, craving, and withdrawal
不同种族群体对尼古丁依赖、渴望和戒断的昼夜节律和睡眠机制
  • 批准号:
    9976302
  • 财政年份:
    2020
  • 资助金额:
    $ 51.39万
  • 项目类别:
Circadian and sleep mechanisms among racial groups for nicotine dependence, craving, and withdrawal
不同种族群体对尼古丁依赖、渴望和戒断的昼夜节律和睡眠机制
  • 批准号:
    10351944
  • 财政年份:
    2020
  • 资助金额:
    $ 51.39万
  • 项目类别:
Circadian and sleep mechanisms among racial groups for nicotine dependence, craving, and withdrawal
不同种族群体对尼古丁依赖、渴望和戒断的昼夜节律和睡眠机制
  • 批准号:
    10612822
  • 财政年份:
    2020
  • 资助金额:
    $ 51.39万
  • 项目类别:

相似海外基金

Examining Social Determinants of Antiretroviral Adherence Trajectories among African American Adults with HIV
检查非洲裔美国成人艾滋病毒感染者抗逆转录病毒药物依从轨迹的社会决定因素
  • 批准号:
    10700611
  • 财政年份:
    2023
  • 资助金额:
    $ 51.39万
  • 项目类别:
Medication Adherence and Cardio-Metabolic Control Indicators among Adult American Indians Receiving Tribal Health Services
接受部落卫生服务的成年美洲印第安人的药物依从性和心脏代谢控制指标
  • 批准号:
    10419967
  • 财政年份:
    2022
  • 资助金额:
    $ 51.39万
  • 项目类别:
Medication Adherence and Cardio-Metabolic Control Indicators among Adult American Indians Receiving Tribal Health Services
接受部落卫生服务的成年美洲印第安人的药物依从性和心脏代谢控制指标
  • 批准号:
    10592441
  • 财政年份:
    2022
  • 资助金额:
    $ 51.39万
  • 项目类别:
Patient Centered Health Technology Medication Adherence Program for African American Hypertensives
以患者为中心的非裔美国人高血压健康技术药物依从计划
  • 批准号:
    9381307
  • 财政年份:
    2017
  • 资助金额:
    $ 51.39万
  • 项目类别:
Exploring Real-time ART Adherence Monitoring In Young African American MSM
探索年轻非裔美国 MSM 的实时 ART 依从性监测
  • 批准号:
    9198162
  • 财政年份:
    2016
  • 资助金额:
    $ 51.39万
  • 项目类别:
PrEP uptake, adherence & retention for African American MSM in Mississippi
PrEP 的摄取、依从性
  • 批准号:
    9141506
  • 财政年份:
    2016
  • 资助金额:
    $ 51.39万
  • 项目类别:
PrEP uptake, adherence & retention for African American MSM in Mississippi
PrEP 的摄取、依从性
  • 批准号:
    9348671
  • 财政年份:
    2016
  • 资助金额:
    $ 51.39万
  • 项目类别:
AMERICAN IMMUNIZATION REGISTRY ASSOC (AIRA) STANDARDS SUPPORT & DEV FOR IMMUNIZATION INFORMATION SYSTEMS TO INCREASE ADHERENCE TO NATL STANDARDS
美国免疫登记协会 (AIRA) 标准支持
  • 批准号:
    8902325
  • 财政年份:
    2014
  • 资助金额:
    $ 51.39万
  • 项目类别:
A smoking cessation/medication adherence intervention for African American MSM
针对非裔美国 MSM 的戒烟/药物依从性干预
  • 批准号:
    8773189
  • 财政年份:
    2013
  • 资助金额:
    $ 51.39万
  • 项目类别:
A smoking cessation/medication adherence intervention for African American MSM
针对非裔美国 MSM 的戒烟/药物依从性干预
  • 批准号:
    8529989
  • 财政年份:
    2013
  • 资助金额:
    $ 51.39万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了