Admin Core

管理核心

• 批准号: 10685454
• 负责人: Karen L Cropsey
• 金额: $ 10.25万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-10 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10685454
• 关键词: Acquired Immunodeficiency Syndrome; Adverse event; Advisory Committees; Alabama; Alcohol consumption; Alcohols; Amendment; Anxiety; Biological Markers; Businesses; Certification; Clinic; Clinical; Clinical Trials Data Monitoring Committees; Cognitive Therapy; Collaborations; Committee Members; Communication; Communities; Coordination and Collaboration; Data Analyses; Data Element; Development; Diagnostic; Disadvantaged; Disparity population; Elements; Emergency Situation; Ensure; Event; Faculty; Fostering; Funding; Gender; Goals; Grant; HIV; Incentives; Individual; Infectious Diseases Research; Infrastructure; Institution; Institutional Review Boards; International; Intervention; Lead; Manuscripts; Mental Health; Mental disorders; Mentors; Methods; Monitor; National Institute on Alcohol Abuse and Alcoholism; Outcome; Pain; Participant; Persons; Policies; Post-Traumatic Stress Disorders; Postdoctoral Fellow; Preparation; Prevention; Program Research Project Grants; Progress Reports; Protocols documentation; Public Sector; Reporting; Research; Research Design; Research Personnel; Research Project Grants; Resource Sharing; Resources; Services; Shipping; Sum; Symptoms; Training; Travel; United States National Institutes of Health; Universities; Work; Zambia; addiction; alcohol comorbidity; alcohol misuse; career; comorbidity; contextual factors; cost; data dissemination; data harmonization; depressive symptoms; effectiveness evaluation; effectiveness testing; human subject; implementation determinants; improved; meetings; multidisciplinary; neighborhood disadvantage; next generation; payment; pre-doctoral; programs; research study; substance use; symposium; treatment effect

ADMINISTRATIVE CORE PROJECT SUMMARY/ABSTRACT The primary objective of the Administrative (Admin) Core is to integrate, coordinate, and manage components of all components of ZAMBAMA (i.e., the two research projects and two additional cores). The Admin core is also responsible for all budgetary (e.g., processing payments, ordering supplies) and regulatory activities (e.g., communication with NIAAA, coordination of Data Safety Monitoring Board activities, IRB activity, tracking adverse events), monitoring and managing overall progress, and promoting coordination and collaboration among investigators within and outside of the program. The Specific Aims of the Admin core are the following: 1) Synchronize scientific aims and foster shared scientific progress between the projects; 2) Manage overarching program business and regulatory requirements; and 3) Enhance collaboration among investigators within and outside of the program. Through this Program Project Grant, we will leverage the infrastructure of our cores, research projects, and infrastructure to achieve our overall aims to 1) better characterize the overlapping burden of mental illness and substance use comorbidity among PLWH with unhealthy alcohol use, 2) evaluate whether and how comorbidity impacts alcohol reduction intervention outcomes, 3) determine the effectiveness of a transdiagnostic cognitive behavioral therapy, and 4) examine implementation factors related to integrated delivery of alcohol reduction interventions to disadvantaged PLWH at front-line HIV clinics. The proposed work is integrated and synergistic, and the Admin Core function to leverage this program’s infrastructure, collaborative relationships, and multidisciplinary expertise to achieve goals that are greater than the sum of its individual parts.

行政核心项目摘要/摘要 管理(管理)核心的主要目标是集成、协调和管理组件 ZAMBAMA的所有组成部分(即两个研究项目和另外两个核心)。管理核心是 还负责所有预算(例如，处理付款、订购用品)和监管活动(例如， 与NIAAA沟通，协调数据安全监测委员会的活动，IRB活动，跟踪 不良事件)，监测和管理总体进展，促进协调和协作 在项目内外的调查人员中。 管理核心的具体目标如下：1)同步科学目标，促进共享科学 项目之间的进度；2)管理总体计划业务和监管要求；以及3) 加强项目内外调查人员之间的合作。通过此计划项目 格兰特，我们将利用我们的核心基础设施、研究项目和基础设施来实现我们的整体 旨在1)更好地描述精神疾病和药物使用共病的重叠负担 不健康饮酒的PLWH，2)评估共病是否以及如何影响饮酒减少 干预结果，3)决定跨诊断认知行为疗法的有效性，以及4) 审查与向弱势群体综合提供减少酒精干预措施有关的执行因素 公共卫生署在前线的艾滋病毒诊所工作。拟议的工作是综合性和协同性的，管理核心职能是 利用该计划的基础设施、协作关系和多学科专业知识来实现 目标大于其各个部分之和的目标。