Augmenting Endoscopic Instruments with Real-time 3D Imaging

通过实时 3D 成像增强内窥镜仪器

• 批准号: 9339459
• 负责人: Steven Yi
• 金额: $ 34.57万
• 依托单位: XYKEN, LLC
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-03-01 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9339459
• 关键词: Address; Affect; Aging; Anatomy; Appearance; Appendicitis; Area; Biopsy; Bronchoscopy; Chronically Ill; Clinic; Clinical; Colon; Colonoscopes; Colonoscopy; Color; Computer software; Cystoscopy; Data; Depth Perception; Devices; Diagnosis; Diagnostic; Digestive System Disorders; Digit structure; Dimensions; Disease; Distal; Documentation; Dose; Elderly; Electronics; Endoscopes; Endoscopy; Equipment; Esophagus; Funding Opportunities; Gases; Gastrointestinal Diseases; Gastrointestinal tract structure; Growth; Hemorrhage; Image; Image-Guided Surgery; Imagery; Impairment; Industry; Inflammatory Bowel Diseases; Laparoscopy; Location; Maintenance; Measurement; Medical; Methods; Modeling; Office Visits; Operative Surgical Procedures; Optics; Patients; Phase; Polyps; Population; Positioning Attribute; Procedures; Process; Publishing; Radiation; Radiation therapy; Recovery; Rectum; Reporting; Research; Research Personnel; Risk; Small Business Innovation Research Grant; Small Intestines; Stomach; Stream; Surface; Surgeon; System; Tablets; Techniques; Technology; Testing; Texture; Therapeutic; Therapeutic Intervention; Three-Dimensional Image; Three-Dimensional Imaging; Time; Tissues; Training; United States; United States National Institutes of Health; Virtual Endoscopy; Visual; Water; aging population; base; capsule; clinical Diagnosis; commercialization; cost; data exchange; design; digital; disease diagnosis; disorder prevention; economic impact; gastrointestinal; imaging system; in vivo; innovation; instrument; lens; miniaturize; minimally invasive; novel; operation; optical imaging; population based; prototype; response; retinal rods; sensor; simulation; software systems; therapeutic effectiveness; tool; two-dimensional

Project Summary: Aging increases the risk of GI disorders such as CRC, inflammatory bowel disease, and appendicitis. NIH statistic shows that 60 to 70 million people are affected by digestive diseases. Increasing global geriatric population base is expected to further worsen this situation over the coming years. Annually, diseases of the gastrointestinal (GI) tract account for more than 30 million office visits and more than 10 million GI endoscopic procedures in the United States alone for the examinations of digestive tract including the esophagus, stomach, small intestine, colon, and rectum. Minimally Invasive Surgery (MIS) endoscopes are still utilized as the main stream with close to $10 billon market needs and near double digit growth rate for performing both diagnosis and therapeutic clinic operations. Unfortunately, existing video based endoscopes can only provide 2D images for visual inspection purpose only, it cannot provide 3D quantitative information on volume and area and location of the disease, as well as the relative position of diagnostic and therapeutic equipment. To address this problem, Xyken together with its collaborator proposes to develop a novel imaging system to provide 2D/3D videoing of the GI anatomical structure. The proposed software system will have the following clinic impact and significance:  Greatly facilitating the diagnosis, planning, and treatment process through quantitative assessment, accurate depth perception and safer navigation  Providing more effective clinical training method for residents/doctors through in-vivo 3D digital GI tract model  Potentially replacing CT based image guided surgery – eliminating radiation and registration caused errors Published research reports find that, driven by the increasing number of the chronically ill population and aging, the global endoscopy equipment market is expected to reach USD 33.6 Billion by 2020 from USD 23.8 Billion in 2015, at a CAGR of 6.1%. With the aging population and advancement of the emerging economies, the global demand is expected to grow with an increased rate. The commercialization potential and economic impact of the proposed system is thus significant.

项目总结: