Wound management through quantitative documentation and prediction

通过定量记录和预测进行伤口管理

• 批准号: 10081799
• 负责人: Steven Yi
• 金额: $ 29.83万
• 依托单位: XYKEN, LLC
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-15 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10081799
• 关键词: 3-Dimensional; Address; Affect; Aging; Algorithms; American; Amputation; Appearance; Area; Artificial Intelligence; Attention; Burn injury; Chronic Care; Classification; Client; Clinical; Computer software; Data; Development; Diabetes Mellitus; Diabetic Foot Ulcer; Diagnosis; Dimensions; Disease; Documentation; Elderly; Epithelial; Epithelium; Evaluation; Evidence based treatment; Feasibility Studies; Goals; Growth; Health Care Costs; Health Technology; Image; Industry; Infection; Information Management; Infrastructure; Laboratories; Limb structure; Measurement; Measures; Medical; Medical Staff; Medical center; Methods; Mobile Health Application; Monitor; Necrosis; Obesity; Outpatients; Patients; Phase; Population; Process; Quality of Care; Secure; Sensitivity and Specificity; Small Business Innovation Research Grant; Stasis Ulcer; System; Technology; Testing; Texas; Time; Tissues; Treatment Cost; Treatment Effectiveness; Treatment Efficacy; Universities; Venous; Visit; Visual Perception; Wound models; acute wound; augmented intelligence; baby boomer; base; care coordination; checkup examination; chronic ulcer; chronic wound; clinical practice; cloud based; cloud platform; computerized data processing; cost; data access; data exchange; data management; decubitus ulcer; design; diabetic; digital; dimensional analysis; empowered; evidence base; healing; individual patient; mHealth; patient home care; personalized care; personalized medicine; phase 1 designs; programs; routine care; sensor; software systems; standard of care; success; tool; treatment planning; trend; wound; wound care; wound healing; wound treatment

Project Summary: We propose in this SBIR effort to develop a mobile health software system for clinicians to conveniently and/or remotely manage and quantitatively document the healing process of chronic ulcers such as diabetic foot ulcers. Timely, frequent, and accurate documentation on wound appearance and dimension is vital for the growth assessment and tracking of treatment effectiveness. However, current practice is subjective, inconsistent, and even invasive. The absence of easily accessible, repeatable, and quantitative data affects care coordination among the medical staffs and handicaps the best treatment planning for individual patients. For chronic wound sufferers, countless routine visits and the ever increasing high treatment costs also hinders their chance of timely treatment and urgently calls for a convenient alternative. Built on a seamlessly integrated client-server framework, the proposed management software allows clinicians to easily exchange wound data with the cloud server, analyze the wound healing information, and manage patient's treatment. Together with potentially other wound sensor data, our software system offers objective and quantitative assessment on wound tissue healing status, avoiding misinterpretation or inconsistent grading among medical staffers. With large patient data to be collected, the proposed software is perceived to assist clinicians with evidence based healing prediction and more effective personalized treatment planning. Every year, approximately 6.5 million Americans suffer from chronic wounds such as diabetic foot ulcers, pressure ulcers, and venous stasis ulcers. The number is projected to grow rapidly due to the aging baby boomer population and a sharp rise in diabetes and obesity. Chronic wound healing is a lengthy process with months or even years of treatment time. Absence of personalized attention could easily cause infections and complications, leading to loss of limb. Evidence suggests that 80% of amputations are actually preventable through access of good quality and routine care. With the ever increasing high healthcare costs and the likelihood of early discharge to home care, patients are highly vulnerable to complications due to the lack of routine checkup or personalized care. All of these validates the urgent need of an alternative, convenient, and low cost clinical practice as what our mobile health app is able to provide.

项目摘要： 我们建议在SBIR努力中为临床医生开发一个移动的健康软件系统， 方便地和/或远程地管理和定量地记录慢性溃疡的愈合过程 例如糖尿病足溃疡。及时、频繁和准确地记录伤口外观， 维度对于生长评估和跟踪治疗效果至关重要。但目前的 实践是主观的，不一致的，甚至是侵入性的。缺乏容易获得的，可重复的， 量化数据影响医护人员之间的护理协调，并妨碍最佳治疗 为个别患者制定计划。对于慢性创伤患者来说，无数的例行检查和 不断增加的高额治疗费用也阻碍了他们及时治疗的机会，迫切需要 方便的替代品。 建立在一个无缝集成的客户端-服务器框架，建议的管理软件 允许临床医生轻松地与云服务器交换伤口数据，分析伤口愈合情况， 信息，并管理患者的治疗。结合潜在的其他伤口传感器数据，我们的 软件系统提供对伤口组织愈合状态的客观和定量评估， 医务人员之间的误解或不一致的分级。由于要收集大量患者数据， 所提出的软件被认为有助于临床医生进行基于证据的愈合预测， 有效的个性化治疗计划。 每年，大约有650万美国人患有慢性伤口，如糖尿病足 溃疡、压迫性溃疡和静脉淤滞性溃疡。预计这一数字将迅速增长， 婴儿潮一代人口老龄化以及糖尿病和肥胖症的急剧上升。慢性伤口愈合是一种 漫长的过程，治疗时间长达数月甚至数年。缺乏个性化的关注可能会 容易引起感染和并发症，导致截肢。有证据表明，80%的 截肢实际上是可以通过获得高质量的日常护理来预防的。随着日益 增加高医疗保健费用和早期出院到家庭护理的可能性， 由于缺乏常规检查或个性化护理，容易出现并发症。所有这些都证实了 迫切需要一种替代的，方便的，低成本的临床实践，作为我们的移动的健康 APP可以提供。