Muscular Dystrophy Cooperative Research Center

项目摘要 核心C的总体目标是提供研究培训和执行其他与教育有关的任务 关于MDCRC特别是，核心C将支持两个医学生奖学金，一个博士后 奖学金，学士后研究实习，和本科研究奖学金。的 医学和博士后研究员和实习生将由核心联合主任（坎贝尔博士）指导 和马修斯），本科生将由他们中的一个指导。的教育努力， 中心是至关重要的，因为迫切需要基础科学家和临床医生谁可以合作， 开发和测试肌营养不良症疗法。通过建立医学生奖学金，我们将 培养下一代神经科医生进行与肌营养不良症相关的转化研究。这满满的- 时间奖学金将使每年两名医学生参加MDCRC的各个方面， 包括：在神经肌肉疾病诊所护理肌肉萎缩症患者; 参与项目2的患者，在马修斯博士的监督下;使用 博士史蒂文·摩尔;并在坎贝尔博士的实验室里研究病人的细胞。最后，这些学生将介绍 在每月一次的神经肌肉疾病会议上，他们从有趣的病例中发现了这些发现。的 博士后研究奖学金将培养科学家在肌肉萎缩症的基础研究， 提供博士，医学博士，或医学博士/博士毕业生在博士密集的研究经验。坎贝尔的 实验室这一经验将通过在临床环境中观察病人护理来补充， 提高研究员对转化研究临床方面的理解和欣赏。的 学士后研究实习旨在鼓励最近的大学毕业生感兴趣的是 攻读研究生学位，通过提供为期一年的密集研究进入转化科学 在进入研究生院之前，有MDCRC实验室的工作经验。本科生研究 奖学金也有类似的目的，但将发放给仍在爱荷华州大学就读的学生; 这些人将与MDCRC实验室的博士后顾问密切合作。最后，爱荷华州 MDCRC将继续其传统，让患者和患者倡导者参与中心，为期两天， 由核心A和项目2主办的会议，以及患者及其家属对中心实验室的图尔斯参观 由Core C托管。会议的目标是教育患者关于正在进行的翻译 在MDCRC的研究，并提供一个论坛，他们可以问有关肌营养不良症的问题 research.这次会议将作为一个很好的培训机会，目前井通研究员 和实习生，他们都将参加会议。通过这些活动，核心C将加速 MDCRC的教育使命，并为临床科学家提供充满活力的培训环境。

PROJECT SUMMARY The overall goals of Core C are to provide research training and carry out other education-related missions of the MDCRC. In particular, Core C will support two Medical Student Fellowships, a Postdoctoral Fellowship, a Post-Baccalaureate Research Internship, and an Undergraduate Research Fellowship. The medical and postdoctoral fellows and the intern will be mentored by both Core Co-Directors (Drs. Campbell and Mathews), and the undergraduate fellow will be mentored by one of them. The educational efforts of the Center are vital because there is an urgent need for basic scientists and clinicians who can partner to develop and test muscular dystrophy therapies. By establishing the Medical Student Fellowship, we will train the next generation of neurologists in translational research related to muscular dystrophy. This full- time fellowship will enable two medical students per year to participate in all aspects of the MDCRC, including: care of muscular dystrophy patients in the neuromuscular disease clinics; clinical evaluation of patients participating in Project 2, under the supervision of Dr. Mathews; evaluation of muscle biopsies with Dr. Steven Moore; and study patient cells in Dr. Campbell's laboratory. Finally, these students will present their findings from interesting cases at the Neuromuscular Disease Conference once a month. The Postdoctoral Research Fellowship will train scientists in the basic research of muscular dystrophy, by providing a PhD, MD, or MD/PhD graduate with an intensive research experience in Dr. Campbell’s laboratory. This experience will be complemented by observation of patient care in a clinical setting, enhancing the fellow’s understanding and appreciation of the clinical side of translational research. The Post-Baccalaureate Research Internship is designed to encourage recent college graduates interested in pursuing graduate degrees to move into translational science by providing a one-year intensive research experience in an MDCRC laboratory before s/he enters graduate school. The Undergraduate Research Fellowship has a similar purpose, but will go to students who are still enrolled at the University of Iowa; these individuals will work closely with a postdoctoral advisor in an MDCRC laboratory. Finally, the Iowa MDCRC will continue its tradition of involving patients and patient advocates in the Center, with a two-day conference hosted by Core A and Project 2 and tours of Center laboratories for patients and their families hosted by Core C. The goal of the conference is to educate the patients about ongoing translational research in the MDCRC and provide a forum where they can ask questions concerning muscular dystrophy research. This conference will serve as an excellent training opportunity for the current Wellstone fellows and intern, all of whom will participate in the conference. Through these activities, Core C will accelerate the education mission of the MDCRC, and provide a vibrant training environment for clinician scientists.