Northern New England Clinical and Translational Research Network

项目摘要 北方新英格兰临床和转化研究（NNE-CTR）网络的使命是 发展和维持临床和转化研究基础设施，支持改善农村和 为缅因州、新罕布什尔州和佛蒙特州的居民提供社区健康服务。这一目标将 通过两个牵头机构的研究人员的互补和协同合作完成， 缅因州医疗中心（缅因州卫生系统的成员）和 佛蒙特大学（ 与 佛蒙特大学健康网络 ），一个参与机构，南缅因州大学，和两个 合作组织，达特茅斯协同临床和转化科学研究所和 达特茅斯初级保健合作研究网络（达特茅斯CO-OP）。 东北部拥有最大的 65岁以上居民的百分比，而NNE-CTR将支持临床和转化研究 在所有类型中，我们的努力将侧重于新北方农村人口的地方性健康问题。 英国，包括癌症，心血管疾病和药物滥用，以及障碍， 影响到农村的卫生保健服务。我们提议的网络的成员有着悠久的历史， 合作，为拟议的网络提供坚实的平台。为了实现这些目标，NNE-CTR 提出了四个具体目标：1）改善基础设施和支持临床和转化研究， 缅因州、新罕布什尔州和佛蒙特州; 2）通过以下方式提高转化和临床研究能力和效力 在NNE-CTR之间建立合作和协同的跨学科研究伙伴关系 机构，由一个积极的试点项目计划的援助; 3）建立创新的培训，指导和 在NNE-CTR机构培养临床和转化科学家的专业发展计划; 以及4）提供基础设施，以支持社区实践和以实践为基础的基层医疗研究 网络，特别是在农村地区，使临床、社区、公共卫生和其他利益攸关方参与 开发和开展与北方新农村地区临床和人口健康需求相关的研究 英格兰为了实现这些目标，NNE-CTR将建立以下关键组成活动： 行政核心;试点项目计划;专业发展核心;临床研究设计， 流行病学和生物统计学核心;农村卫生研究和提供核心;转化研究 技术核心;以及跟踪和评估核心。总之，通过发展能力和 研究所需的资源跨越广泛的临床和转化科学，NNE- CTR将为加强临床研究和医疗保健提供平台，以支持独特的 北方新英格兰农村的需要。

PROJECT SUMMARY The mission of the Northern New England Clinical and Translational Research (NNE-CTR) Network is to develop and sustain a clinical and translational research infrastructure that supports improvement in rural and community health for inhabitants in the IDeA states of Maine, New Hampshire and Vermont. This goal will be accomplished through complementary and synergistic collaborations of investigators in two lead institutions, Maine Medical Center (a member of the MaineHealth System) and the University of Vermont ( with the University of Vermont Health Network ), one participating institution, the University of Southern Maine, and two collaborating organizations, the Dartmouth SYNERGY Clinical and Translational Science Institute and the Dartmouth Primary Care Cooperative Research Network (Dartmouth CO-OP). The Northeast has the largest percentage of residents over 65 years of age, and while NNE-CTR will support clinical and translational studies of all types, our efforts will emphasize health problems endemic in the rural populations of northern New England, including cancer, cardiovascular disease, and substance abuse, as well as the barriers that compromise rural health care delivery. The members of our proposed network have a long history of collaboration, providing a solid platform for the proposed network. To accomplish these goals, NNE-CTR proposes four specific aims: 1) improve the infrastructure and support for clinical and translational research in Maine, New Hampshire and Vermont; 2) increase translational and clinical research capacity and efficacy by establishing collaborative and synergistic transdisciplinary research partnerships among the NNE-CTR institutions, aided by a vigorous Pilot Projects program; 3) establish innovative training, mentoring and professional development programs to develop clinical and translational scientists at the NNE-CTR institutions; and 4) provide the infrastructure to support community practices and practice-based primary care research networks, particularly in rural areas, to engage clinical, community, public health and other stakeholders in the development and conduct of research relevant to the clinical and population health needs of northern New England. To achieve these aims, NNE-CTR will establish the following Key Component Activities: Administrative Core; Pilot Projects Program; Professional Development Core; Clinical Research Design, Epidemiology and Biostatistics Core; Rural Health Research and Delivery Core; Translational Research Technologies Core; and the Tracking and Evaluation Core. In summary, by developing the capabilities and resources required for research spanning the broad spectrum of clinical and translational science, the NNE- CTR will provide the platform for enhancing clinical research and health care delivery to support the unique needs of rural northern New England.