Administrative Core

行政核心

• 批准号: 9315977
• 负责人: ROBERT Kernachan HEATON
• 金额: $ 13.4万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-22 至 2021-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9315977
• 关键词: Address; Advocate; Charge; Collaborations; Communication; Communities; Consult; Data; Decision Making; Doctor of Philosophy; Ensure; Evaluation; Feedback; Fostering; Future; Goals; HIV; Home environment; Information Dissemination; Institution; Institutional Policy; Institutional Review Boards; Interdisciplinary Study; Leadership; Maintenance; Management Information Systems; Manuscripts; Modality; Monitor; Participant; Policies; Process; Provider; Recruitment Activity; Registries; Reporting; Research; Research Personnel; Research Project Grants; Resource Allocation; Resources; Review Committee; Staging; Strategic Planning; Structure; Study Subject; United States National Institutes of Health; Universities; Videoconferences; Videoconferencing; Vision; abstracting; cohort; data management; design; federal policy; human subject; interest; meetings; method development; neuroAIDS; neurobehavioral; operation; statistical service; statistics; web site; working group

ADMINISTRATIVE CORE PROJECT SUMMARY/ABSTRACT: The Administrative Core provides the overall scientific leadership and management for the HNRC, with a primary aim of ensuring integrated, coherent, and effective scientific operations. Within the Core, the Executive Team (ET) provides programmatic leadership and oversight of the Center regarding resource allocation and future research directions and projects. The decisions of the ET are informed by both external and internal formal review, advice and feedback. The external Scientific Advisory Board meets annually to evaluate Center progress and to recommend future scientific directions. Internally, the Council of Investigators sets policy and closely monitors scientific progress. Valued local input to the ET also comes from the Community Advisory Board (community providers, advocates, and leaders) and Participant Advisory Board (study participants). The leadership's key decision- making functions are implemented via four interacting components: the Coordinating Unit which has overall responsibility for executing and coordinating Center activities, including organizing the distribution of Center resources, facilitating information dissemination to scientific and general communities, and ensuring compliance with institutional and Federal policies; the Data Management and Statistics Unit , which processes all Center-related data, ensures seamless interaction among Cores and associated projects, and supports Center websites and videoconferencing; the Statistics Unit , which provides statistical services at all study stages, from design to final analyses; and the Participant Accrual and Retention Unit, which recruits cohorts of interest, maintains the longitudinal cohort, and manages a registry of potential study participants. Each of these Units also engages in methods development. In addition, strong working groups assist and guide the Core: the Research Review Committee reviews requests for Center resources and serves as a venue for the discussion of current and proposed studies and manuscripts; the HNRC Operations Workgroup, in which key managers and project coordinators address project implementation and troubleshooting, and the Human Subjects Committee, which monitors human subjects and IRB issues, particularly relating to safeguarding confidentiality. The structures and processes of the Core ensure the operation of a truly multidisciplinary research center and foster a wide-ranging nimbleness and responsiveness not only to priorities announced at the national level by policy (e.g., the NIH) and those expressed by the national neuroAIDS research community (e.g., our nation-  wide collaborating universities), but also within our home institution (HNRC scientific Core leaders, other UCSD HIV research groups).

行政核心项目摘要/摘要：管理核心提供总体 HNRC的科学领导力和管理，主要目的是确保融合，连贯和 有效的科学操作。在核心内，执行团队（ET）提供程序化领导 以及对资源分配以及未来研究方向和项目的监督。 ET的决定由外部和内部正式审查，建议和反馈来告知。这 外部科学咨询委员会每年开会以评估中心的进度并推荐未来 科学方向。在内部，调查人员理事会制定了政策，并密切监视科学进步。 ET的当地有价值的投入也来自社区顾问委员会（社区提供者， 倡导者和领导者）和参与者顾问委员会（研究参与者）。领导人的关键决定 - 通过四个相互作用组件实现制作功能：具有总体的协调单元 执行和协调中心活动的责任，包括组织中心的分配 资源，支持向科学和一般社区传播信息，并确保 遵守机构和联邦政策；数据管理和统计单元，该单元正在处理 所有与中心相关的数据，确保核心和相关项目之间的无缝互动，并支持 中心网站和视频会议；统计单位，在所有研究中提供统计服务 阶段，从设计到最终分析；以及参与者的应计和保留单位，该单位报告 兴趣，维护纵向队列，并管理潜在研究参与者的注册表。每个 单位还从事方法开发。此外，强大的工作组协助和指导核心： 研究审查委员会审查中心资源的请求，并作为讨论的场所 当前和提议的研究和手稿； HNRC操作工作组，其中关键经理 项目协调员解决项目实施和故障排除，以及人类主题 委员会监视人类受试者和IRB问题，尤其是与保护机密性有关的委员会。 核心的结构和过程确保了真正的多学科研究中心的运行 培养广泛的灵活性和响应能力，不仅是对国家一级宣布的优先事项 政策（例如NIH）和国家神经辅助研究界（例如，我们的民族）表达的政策 广泛合作的大学），也包括我们的家庭机构（HNRC科学核心领导者，其他UCSD 艾滋病毒研究小组）。