Training in Research on Addictions in Interdisciplinary NeuroAIDS (TRAIN)

 描述（由申请人提供）：关于药物滥用和HIV感染对中枢神经系统（CNS）的联合影响的跨学科临床研究与公共卫生倡议具有相当大的相关性。然而，目前很少有实验室进行这样的研究和（除了我们）没有目前的培训计划，专门准备在这一关键领域的下一代研究人员。在其第一个资助期或露丝L Kirschstein国家研究服务奖机构培训补助金（NRSA T32）题为“跨学科神经艾滋病成瘾研究培训”，汇集了一批才华横溢、文化多样的博士前和博士后学员、一个有成就的多学科导师团队、一个有效的行政结构和广泛的学术资源，在培养国家下一代学者领导药物滥用和神经艾滋病领域方面，现在已经有了良好的记录。在当前资助期间，9名学生和研究员取得了显着的生产力：他们总共在科学文献中发表了近60篇手稿（24岁，第一作者），并在科学会议上发表了70多篇演讲。（28第一作者）;他们还成功地竞争了5校外和3校内赠款，以进一步他们的研究; 3人获得了新的教员或研究科学家职位。因此，我们建议更新TRAIN，以便在这些成功的基础上为该领域的未来发展奠定基础。它的目的是准备一个稳定的状态，三个博士前和两个博士后实习生在临床神经心理学的多学科学术生涯集中在药物滥用和艾滋病毒感染的中枢神经系统的影响，与这些共病条件老化的新主题。TRAIN强调在三个主要的、相互关联的CNS结果方面的研究培训，这些结果是根据其科学和

 DESCRIPTION (provided by applicant): Interdisciplinary clinical research on the combined effects of substance abuse and HIV infection on the central nervous system (CNS) is of considerable relevance to public health initiatives. However, there are presently few laboratories conducting such research and (aside from ours) no current training programs dedicated to preparing the next generation of investigators in this critical area. In its first funding period or Ruth L Kirschstein National Research Service Award Institutional Training Grant (NRSA T32) entitled, "Training in Research on Addictions in Interdisciplinary NeuroAIDS (TRAIN)" has brought together a talented and culturally diverse cohort of pre- and post-doctoral trainees, an accomplished multidisciplinary team of mentors, an effective administrative structure, and a broad array of academic resources, with what is now a proven track record in preparing the Nation's next generation of academics to lead the field of substance abuse and neuroAIDS. The 9 students and fellows mentored during the current funding period have achieved remarkable productivity: In total, they have published nearly 60 manuscripts in the scientific literature (24 s first author) and have made over 70 presentations in scientific conferences (28 first authored); they also have successfully competed for 5 extramural and 3 intramural grants to further their research; and 3 have obtained new faculty or research scientist positions. Accordingly, we propose a renewal of TRAIN to build on these successes for the future of the field. Its aim is to prepare a steady state of three pre-doctoral and two post-doctoral trainees in clinical neuropsychology for multidisciplinary academic careers focused on the CNS effects of substance abuse and HIV infection, with a new theme on aging with these comorbid conditions. TRAIN emphasizes research training in three primary, interrelated CNS outcomes, which were selected for their scientific and